| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | lactotransferrin|This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 4057) |
| External Link | https://ncbi.nlm.nih.gov/gene/4057 |
| Similar Terms | |
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498 genes differentially expressed following the LTF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0144565 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0137079 |
| ASS1 | argininosuccinate synthase 1 | 0.0121949 |
| MGLL | monoglyceride lipase | 0.0119874 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0119406 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0118313 |
| GNAS | GNAS complex locus | 0.0116793 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0115264 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0113309 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.0110886 |
| INSR | insulin receptor | 0.0110566 |
| RGS5 | regulator of G-protein signaling 5 | 0.0108081 |
| MAP7 | microtubule-associated protein 7 | 0.010783 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0107586 |
| HOXC6 | homeobox C6 | 0.00981068 |
| S100P | S100 calcium binding protein P | 0.00978827 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0097351 |
| C7 | complement component 7 | 0.00949482 |
| NAV2 | neuron navigator 2 | 0.00949202 |
| ANXA3 | annexin A3 | 0.00948278 |
| TRIM44 | tripartite motif containing 44 | 0.00944746 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00935731 |
| MVP | major vault protein | 0.00930012 |
| KRT7 | keratin 7, type II | 0.00924913 |
| KRT18 | keratin 18, type I | 0.00923055 |
| G0S2 | G0/G1 switch 2 | 0.00913603 |
| RGS16 | regulator of G-protein signaling 16 | 0.00907178 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00895785 |
| NEFH | neurofilament, heavy polypeptide | 0.00888384 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00885421 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00871566 |
| ZNF721 | zinc finger protein 721 | 0.00870406 |
| PXDN | peroxidasin | 0.00866656 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00866481 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00860034 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00842595 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00841947 |
| AUTS2 | autism susceptibility candidate 2 | 0.00835448 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00830564 |
| NOTCH2NL | notch 2 N-terminal like | 0.00825241 |
| CLU | clusterin | 0.00823813 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00821474 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00819669 |
| RET | ret proto-oncogene | 0.0081895 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00816895 |
| STK10 | serine/threonine kinase 10 | 0.0081676 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00815584 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.008153 |
| TFF1 | trefoil factor 1 | 0.0081517 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00801077 |
| NCOA6 | nuclear receptor coactivator 6 | 0.00797443 |
| ZNF160 | zinc finger protein 160 | 0.00796728 |
| PCDH9 | protocadherin 9 | 0.00795917 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00792658 |
| AGTR1 | angiotensin II receptor, type 1 | 0.0079149 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 | 0.00791481 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00785034 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00784701 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00776422 |
| TAC1 | tachykinin, precursor 1 | 0.00774959 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00774116 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00768537 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00762616 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00762021 |
| KAZN | kazrin, periplakin interacting protein | 0.00761031 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00758466 |
| THBS4 | thrombospondin 4 | 0.00758293 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00755248 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00749806 |
| AMOTL2 | angiomotin like 2 | 0.00748784 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00744252 |
| ELAC2 | elaC ribonuclease Z 2 | 0.00743678 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00741045 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00737905 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0073711 |
| LAMB1 | laminin, beta 1 | 0.00736465 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00732279 |
| VCL | vinculin | 0.00731439 |
| HMOX1 | heme oxygenase 1 | 0.00727863 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00724053 |
| NPTX2 | neuronal pentraxin II | 0.00724006 |
| DUSP4 | dual specificity phosphatase 4 | 0.00720246 |
| FAM13A | family with sequence similarity 13, member A | 0.00715891 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00713647 |
| IRS2 | insulin receptor substrate 2 | 0.00709141 |
| JMJD6 | jumonji domain containing 6 | 0.00706484 |
| GOLGA8H | golgin A8 family, member H | 0.00705596 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.00703937 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00702699 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00702047 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00699627 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00698455 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00696994 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00696077 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00695902 |
| JADE1 | jade family PHD finger 1 | 0.00694729 |
| CUX1 | cut-like homeobox 1 | 0.00692537 |
| RND3 | Rho family GTPase 3 | 0.00692351 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00690375 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00690037 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00688867 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.00688565 |
| IRF7 | interferon regulatory factor 7 | 0.00685533 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.00683503 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00683333 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00680381 |
| REEP1 | receptor accessory protein 1 | 0.00680009 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00679823 |
| WDR45 | WD repeat domain 45 | 0.00677518 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00675889 |
| FBN2 | fibrillin 2 | 0.00675216 |
| MB | myoglobin | 0.00674051 |
| MAGEA12 | melanoma antigen family A12 | 0.00671042 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.00670571 |
| PLIN2 | perilipin 2 | 0.00670251 |
| JUND | jun D proto-oncogene | 0.00669402 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00669395 |
| TSPAN13 | tetraspanin 13 | 0.00668374 |
| GOLGA8A | golgin A8 family, member A | 0.00666043 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00665935 |
| RRAGC | Ras-related GTP binding C | 0.00662527 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00661505 |
| ADCY9 | adenylate cyclase 9 | 0.00659646 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0065691 |
| RBM26 | RNA binding motif protein 26 | 0.00655569 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0065069 |
| L1CAM | L1 cell adhesion molecule | 0.00649905 |
| TPBG | trophoblast glycoprotein | 0.00645871 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00644709 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00641242 |
| CDV3 | CDV3 homolog (mouse) | 0.00640899 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0063833 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.00637362 |
| DST | dystonin | 0.00636254 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00635644 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00635624 |
| TXLNA | taxilin alpha | 0.00634177 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.00633197 |
| DCLK1 | doublecortin-like kinase 1 | 0.00632732 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00631469 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00629917 |
| PROM1 | prominin 1 | 0.00629626 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00627893 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0062726 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.00626812 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00626618 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00626547 |
| FRY | furry homolog (Drosophila) | 0.00625901 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00624492 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00624057 |
| COLEC11 | collectin sub-family member 11 | 0.00623804 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00622933 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.00620724 |
| KIF1A | kinesin family member 1A | 0.00618169 |
| MAGEA1 | melanoma antigen family A1 | 0.00617414 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00615662 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00613371 |
| PHF8 | PHD finger protein 8 | 0.00612463 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00611213 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00609083 |
| EHD3 | EH-domain containing 3 | 0.00608862 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00608432 |
| MEOX2 | mesenchyme homeobox 2 | 0.00607995 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00607915 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00606371 |
| BEX1 | brain expressed, X-linked 1 | 0.0060443 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00603931 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00603391 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00600848 |
| FAM193A | family with sequence similarity 193, member A | 0.00600735 |
| C9 | complement component 9 | 0.00600601 |
| FILIP1L | filamin A interacting protein 1-like | 0.00599936 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.00599552 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00598166 |
| AREG | amphiregulin | 0.00598112 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00597777 |
| RGS3 | regulator of G-protein signaling 3 | 0.00597345 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.0059458 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00594066 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00592848 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00591683 |
| MID1 | midline 1 | 0.00590454 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00589279 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | 0.00588878 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00587493 |
| NRXN3 | neurexin 3 | 0.00585325 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.00585094 |
| C19ORF54 | chromosome 19 open reading frame 54 | 0.00585032 |
| USP11 | ubiquitin specific peptidase 11 | 0.00583683 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00583629 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00583414 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00582633 |
| SETD5 | SET domain containing 5 | 0.00582032 |
| SQSTM1 | sequestosome 1 | 0.00581606 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00578735 |
| CTSA | cathepsin A | 0.00578262 |
| PRR11 | proline rich 11 | 0.00577405 |
| ACKR3 | atypical chemokine receptor 3 | 0.00575451 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | 0.00575034 |
| MATN2 | matrilin 2 | 0.0057438 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00572773 |
| RETREG2 | reticulophagy regulator family member 2 | 0.00572691 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00572377 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00570407 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00570178 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00569493 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.00568693 |
| MAGED2 | melanoma antigen family D2 | 0.00568395 |
| CRAT | carnitine O-acetyltransferase | 0.00567395 |
| PLCB4 | phospholipase C, beta 4 | 0.00567073 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0056574 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00563321 |
| ZNF165 | zinc finger protein 165 | 0.0056209 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.00561397 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00560328 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00560269 |
| CTSL | cathepsin L | 0.00559598 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00559398 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.00559321 |
| AGR2 | anterior gradient 2 | 0.00559303 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00557755 |
| NUCLEOLIN | nucleolin multifunctional protein | 0.00557502 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.0055726 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00557238 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00557195 |
| HEATR1 | HEAT repeat containing 1 | 0.00556961 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00556555 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00556491 |
| RASA4 | RAS p21 protein activator 4 | 0.00556322 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.00555331 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00554659 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00554418 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00554354 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00554165 |
| CDK11A | cyclin-dependent kinase 11A | 0.00554063 |
| FOXJ3 | forkhead box J3 | 0.00553666 |
| LAMA5 | laminin, alpha 5 | 0.00553541 |
| FNBP4 | formin binding protein 4 | 0.00553362 |
| F9 | coagulation factor IX | 0.00553233 |
| PHIP | pleckstrin homology domain interacting protein | 0.00553119 |
| SRRT | serrate, RNA effector molecule | 0.00551181 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00550412 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | 0.00550102 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00549908 |
| NLGN4X | neuroligin 4, X-linked | 0.00549777 |
| ZNF611 | zinc finger protein 611 | 0.00549284 |
| GUSB | glucuronidase, beta | 0.00548646 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0054783 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00547421 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00546115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | -0.0160945 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0130998 |
| EVI2A | ecotropic viral integration site 2A | -0.0130626 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0127641 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0125127 |
| KRT15 | keratin 15, type I | -0.0124937 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0116551 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.0115889 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0115431 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0113795 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.0108152 |
| RGS10 | regulator of G-protein signaling 10 | -0.0107779 |
| KRT5 | keratin 5, type II | -0.0106852 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0106597 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0105496 |
| CTSH | cathepsin H | -0.0104057 |
| POSTN | periostin, osteoblast specific factor | -0.0103715 |
| PLAU | plasminogen activator, urokinase | -0.0103106 |
| CD48 | CD48 molecule | -0.00980482 |
| RGCC | regulator of cell cycle | -0.00966357 |
| CD9 | CD9 molecule | -0.00950485 |
| TMEM14B | transmembrane protein 14B | -0.00927842 |
| LCN2 | lipocalin 2 | -0.00910518 |
| EGR2 | early growth response 2 | -0.00903343 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00894243 |
| S100A7 | S100 calcium binding protein A7 | -0.00890773 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0088901 |
| S100A9 | S100 calcium binding protein A9 | -0.00886265 |
| CSTA | cystatin A (stefin A) | -0.00870435 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00857107 |
| MSMB | microseminoprotein, beta- | -0.00855171 |
| S100A2 | S100 calcium binding protein A2 | -0.0085436 |
| BCL2A1 | BCL2-related protein A1 | -0.00851734 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00835824 |
| EMP1 | epithelial membrane protein 1 | -0.00830377 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00830282 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00828017 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00825391 |
| RPA3 | replication protein A3, 14kDa | -0.00819317 |
| TMEM14A | transmembrane protein 14A | -0.00813796 |
| HOPX | HOP homeobox | -0.00802075 |
| NDP | Norrie disease (pseudoglioma) | -0.00790467 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00782768 |
| DOCK4 | dedicator of cytokinesis 4 | -0.00781135 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00777786 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00770519 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00768241 |
| DCK | deoxycytidine kinase | -0.00766678 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00763039 |
| KRT6A | keratin 6A, type II | -0.00762225 |
| PITX1 | paired-like homeodomain 1 | -0.00756641 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00752575 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00751519 |
| AK4 | adenylate kinase 4 | -0.00751207 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00750788 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00750416 |
| LY96 | lymphocyte antigen 96 | -0.00743605 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00742145 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00739349 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00737716 |
| FABP7 | fatty acid binding protein 7, brain | -0.00732693 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00729086 |
| WDR61 | WD repeat domain 61 | -0.00729071 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00724214 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00720634 |
| S100A8 | S100 calcium binding protein A8 | -0.00715916 |
| TSPAN6 | tetraspanin 6 | -0.00714769 |
| CCK | cholecystokinin | -0.00712697 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0071255 |
| FAM198B | family with sequence similarity 198, member B | -0.00706464 |
| LUM | lumican | -0.00701947 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00700863 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00700716 |
| MAL | mal, T-cell differentiation protein | -0.00699798 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00698866 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | -0.00696176 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00695993 |
| RANBP1 | RAN binding protein 1 | -0.00695326 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00690875 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00684905 |
| METRN | meteorin, glial cell differentiation regulator | -0.00684646 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00683805 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00683203 |
| CHI3L2 | chitinase 3-like 2 | -0.00682936 |
| CALML3 | calmodulin-like 3 | -0.00679564 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.00677792 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -0.0067686 |
| TLR1 | toll-like receptor 1 | -0.00676602 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00675714 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.0067512 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.0067257 |
| DAZAP2 | DAZ associated protein 2 | -0.00671828 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00671565 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -0.00670043 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00669734 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00668089 |
| CRIPT | cysteine-rich PDZ-binding protein | -0.006667 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00664543 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00664358 |
| EXOSC4 | exosome component 4 | -0.00660414 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00655025 |
| FPR3 | formyl peptide receptor 3 | -0.00654811 |
| CEL | carboxyl ester lipase | -0.00653581 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.00651638 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00651429 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00651002 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00646282 |
| CD52 | CD52 molecule | -0.00645915 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.0064493 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00643367 |
| ANXA1 | annexin A1 | -0.00642813 |
| PMP22 | peripheral myelin protein 22 | -0.0064278 |
| GLUL | glutamate-ammonia ligase | -0.00642404 |
| ATG5 | autophagy related 5 | -0.00641485 |
| HIST3H2A | histone cluster 3, H2a | -0.00640002 |
| LPXN | leupaxin | -0.00639427 |
| SGMS1 | sphingomyelin synthase 1 | -0.00639279 |
| ADORA2B | adenosine A2b receptor | -0.00638787 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00638277 |
| KRT6B | keratin 6B, type II | -0.00637421 |
| RPS5 | ribosomal protein S5 | -0.00637013 |
| IL1RN | interleukin 1 receptor antagonist | -0.00635028 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.0063492 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00633775 |
| CNN3 | calponin 3, acidic | -0.00632186 |
| MDFIC | MyoD family inhibitor domain containing | -0.00629673 |
| KRT16 | keratin 16, type I | -0.00626087 |
| POP4 | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | -0.00624902 |
| WBP5 | WW domain binding protein 5 | -0.00624591 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00623204 |
| SSR1 | signal sequence receptor, alpha | -0.00623055 |
| GPR65 | G protein-coupled receptor 65 | -0.00622672 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00621736 |
| COMMD10 | COMM domain containing 10 | -0.0062009 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00617686 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00617041 |
| POLB | polymerase (DNA directed), beta | -0.00616065 |
| SLAMF7 | SLAM family member 7 | -0.00614372 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00610215 |
| SPRR1B | small proline-rich protein 1B | -0.00610016 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.006084 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0060814 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00608112 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00607879 |
| DUSP22 | dual specificity phosphatase 22 | -0.0060778 |
| CD2 | CD2 molecule | -0.00607461 |
| SPRR2B | small proline-rich protein 2B | -0.00607236 |
| COMMD8 | COMM domain containing 8 | -0.00606362 |
| KRT13 | keratin 13, type I | -0.00605904 |
| KRT14 | keratin 14, type I | -0.00605609 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | -0.00604873 |
| NUP37 | nucleoporin 37kDa | -0.00602743 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00602248 |
| SS18L2 | synovial sarcoma translocation gene on chromosome 18-like 2 | -0.00601286 |
| COMMD3 | COMM domain containing 3 | -0.00600126 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.00599962 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -0.00599177 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0059637 |
| ABI1 | abl-interactor 1 | -0.00596317 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00595898 |
| H1-0 | H1.0 linker histone | -0.00594275 |
| CDK1 | cyclin-dependent kinase 1 | -0.00593321 |
| SLA | Src-like-adaptor | -0.00593286 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00592807 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00592739 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00591816 |
| ORC5 | origin recognition complex, subunit 5 | -0.00591056 |
| CSTB | cystatin B (stefin B) | -0.00591043 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00590588 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00590089 |
| CLDND1 | claudin domain containing 1 | -0.005896 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00588735 |
| CLCA4 | chloride channel accessory 4 | -0.00588591 |
| ANKRD46 | ankyrin repeat domain 46 | -0.00586423 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.00585088 |
| SPRR1A | small proline-rich protein 1A | -0.00583733 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.0058352 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00583377 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00582894 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00582044 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00581981 |
| CENPU | centromere protein U | -0.00580814 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00580106 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00579 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00577141 |
| RPA2 | replication protein A2, 32kDa | -0.00575467 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00575015 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.00574662 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00573715 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00573547 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00573532 |
| PRKD3 | protein kinase D3 | -0.00572794 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00570636 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00569431 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00568999 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00568601 |
| KRT17 | keratin 17, type I | -0.00567841 |
| VSNL1 | visinin-like 1 | -0.00567558 |
| IL10RA | interleukin 10 receptor, alpha | -0.00567492 |
| CTSS | cathepsin S | -0.00566635 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00566578 |
| UBE2N | ubiquitin-conjugating enzyme E2N | -0.00566289 |
| MMP7 | matrix metallopeptidase 7 | -0.00566042 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00565675 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.00562553 |
| HNMT | histamine N-methyltransferase | -0.00562309 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00561589 |
| NAGK | N-acetylglucosamine kinase | -0.0056124 |
| CD84 | CD84 molecule | -0.00561077 |
| ZFAND1 | zinc finger, AN1-type domain 1 | -0.00560792 |
| SNU13 | small nuclear ribonucleoprotein 13 | -0.00560636 |
| CD14 | CD14 molecule | -0.00558324 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00556783 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00556249 |
| ARF4 | ADP-ribosylation factor 4 | -0.00556034 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00554881 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00554268 |
| STXBP2 | syntaxin binding protein 2 | -0.00553478 |
| BAG2 | BCL2-associated athanogene 2 | -0.00552559 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0055237 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00552342 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.0055195 |
| MMP1 | matrix metallopeptidase 1 | -0.00551576 |
| SMIM8 | small integral membrane protein 8 | -0.00550924 |
| CALR | calreticulin | -0.00550062 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial | -0.00548791 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00548634 |
| UBA3 | ubiquitin-like modifier activating enzyme 3 | -0.00547782 |
| TMEM165 | transmembrane protein 165 | -0.00547702 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00546893 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00545622 |
| SELENOF | selenoprotein F | -0.00545483 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | -0.00545295 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.0054379 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00543744 |
| SULF1 | sulfatase 1 | -0.00543296 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00542975 |
| MRS2 | MRS2 magnesium transporter | -0.00542064 |
| TCTA | T-cell leukemia translocation altered | -0.00541502 |
| CLDN10 | claudin 10 | -0.00540998 |
| DNASE2 | deoxyribonuclease II, lysosomal | -0.0054082 |
| C5ORF28 | chromosome 5 open reading frame 28 | -0.00540456 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00540223 |
| TMPRSS11D | transmembrane protease, serine 11D | -0.00537487 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00537397 |
| TAGLN2 | transgelin 2 | -0.00537214 |
| CDCA4 | cell division cycle associated 4 | -0.00536116 |
| A2M | alpha-2-macroglobulin | -0.00535173 |
