LTF Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description lactotransferrin|This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 4057)
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Genes

437 target genes of the LTF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABHD12 abhydrolase domain containing 12
ACD adrenocortical dysplasia homolog (mouse)
ACP6 acid phosphatase 6, lysophosphatidic
ACSM2B acyl-CoA synthetase medium-chain family member 2B
ADA adenosine deaminase
ADAR adenosine deaminase, RNA-specific
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKIP1 A kinase (PRKA) interacting protein 1
ALDH1L1-AS2 ALDH1L1 antisense RNA 2
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALOXE3 arachidonate lipoxygenase 3
ALPK1 alpha-kinase 1
AMBP alpha-1-microglobulin/bikunin precursor
ANKRD11 ankyrin repeat domain 11
ANKRD24 ankyrin repeat domain 24
ANO1 anoctamin 1, calcium activated chloride channel
ANO2 anoctamin 2, calcium activated chloride channel
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
AQP6 aquaporin 6, kidney specific
ARHGAP24 Rho GTPase activating protein 24
ARHGAP26 Rho GTPase activating protein 26
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB7 ankyrin repeat and SOCS box containing 7
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATXN7 ataxin 7
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCAP31 B-cell receptor-associated protein 31
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BMP2 bone morphogenetic protein 2
BOC BOC cell adhesion associated, oncogene regulated
BPIFB2 BPI fold containing family B, member 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTNL2 butyrophilin-like 2
C10ORF90 chromosome 10 open reading frame 90
C12ORF74 chromosome 12 open reading frame 74
C1ORF159 chromosome 1 open reading frame 159
C1ORF233 chromosome 1 open reading frame 233
C2CD2 C2 calcium-dependent domain containing 2
C3ORF67 chromosome 3 open reading frame 67
C5ORF30 chromosome 5 open reading frame 30
C8ORF74 chromosome 8 open reading frame 74
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C-AS4 CACNA1C antisense RNA 4
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMP cathelicidin antimicrobial peptide
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CARD14 caspase recruitment domain family, member 14
CCDC136 coiled-coil domain containing 136
CCDC146 coiled-coil domain containing 146
CCDC155 coiled-coil domain containing 155
CCDC40 coiled-coil domain containing 40
CCDC88B coiled-coil domain containing 88B
CD300LF CD300 molecule-like family member f
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDCA7L cell division cycle associated 7-like
CDH5 cadherin 5, type 2 (vascular endothelium)
CEP152 centrosomal protein 152kDa
CFL1P1 cofilin 1 (non-muscle) pseudogene 1
CHDH choline dehydrogenase
CLCN5 chloride channel, voltage-sensitive 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLRN2 clarin 2
CLUAP1 clusterin associated protein 1
CLVS1 clavesin 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CNTN4 contactin 4
COBL cordon-bleu WH2 repeat protein
COL11A2 collagen, type XI, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRB2 crumbs family member 2
CRCT1 cysteine-rich C-terminal 1
CRTC1 CREB regulated transcription coactivator 1
CRYL1 crystallin, lambda 1
CSNK1D casein kinase 1, delta
CXCR6 chemokine (C-X-C motif) receptor 6
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCC DCC netrin 1 receptor
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND2D DENN/MADD domain containing 2D
DES desmin
DESI1 desumoylating isopeptidase 1
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLK1 delta-like 1 homolog (Drosophila)
DMTN dematin actin binding protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNM3 dynamin 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOC2A double C2-like domains, alpha
DOCK11 dedicator of cytokinesis 11
DOCK9 dedicator of cytokinesis 9
DOK7 docking protein 7
DPEP2 dipeptidase 2
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DTNB dystrobrevin, beta
DZIP1L DAZ interacting zinc finger protein 1-like
ECT2 epithelial cell transforming 2
EFHC1 EF-hand domain (C-terminal) containing 1
EFHC2 EF-hand domain (C-terminal) containing 2
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EGR4 early growth response 4
EMC9 ER membrane protein complex subunit 9
EML1 echinoderm microtubule associated protein like 1
ENGASE endo-beta-N-acetylglucosaminidase
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41 erythrocyte membrane protein band 4.1
EPHA6 EPH receptor A6
EPHA8 EPH receptor A8
ERP29 endoplasmic reticulum protein 29
EWSR1 EWS RNA-binding protein 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FABP7 fatty acid binding protein 7, brain
FAM131B family with sequence similarity 131, member B
FAM173A family with sequence similarity 173, member A
FAM185A family with sequence similarity 185, member A
FAM186B family with sequence similarity 186, member B
FAM193B family with sequence similarity 193, member B
FBXO25 F-box protein 25
FEV FEV (ETS oncogene family)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKSG29 FKSG29
FLOT2 flotillin 2
FOXD2 forkhead box D2
FOXE3 forkhead box E3
FTO fat mass and obesity associated
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAS1 growth arrest-specific 1
GBA glucosidase, beta, acid
GBAP1 glucosidase, beta, acid pseudogene 1
GDF11 growth differentiation factor 11
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJC2 gap junction protein, gamma 2, 47kDa
GLIPR1 GLI pathogenesis-related 1
GPBP1 GC-rich promoter binding protein 1
GPR20 G protein-coupled receptor 20
GPR61 G protein-coupled receptor 61
GRAMD1B GRAM domain containing 1B
GRK6 G protein-coupled receptor kinase 6
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTSE1-AS1 GTSE1 antisense RNA 1 (head to head)
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCRT hypocretin (orexin) neuropeptide precursor
HDGFL1 hepatoma derived growth factor-like 1
HDGFRP2 hepatoma-derived growth factor-related protein 2
HEATR1 HEAT repeat containing 1
HIC2 hypermethylated in cancer 2
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene)
HLF hepatic leukemia factor
HLX H2.0-like homeobox
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOMER3 homer scaffolding protein 3
HOXD3 homeobox D3
HPS4 Hermansky-Pudlak syndrome 4
HR hair growth associated
HS1BP3 HCLS1 binding protein 3
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
IER3 immediate early response 3
IFNAR2 interferon (alpha, beta and omega) receptor 2
IGF2R insulin-like growth factor 2 receptor
IL16 interleukin 16
IL1F10 interleukin 1 family, member 10 (theta)
IL20 interleukin 20
IMPG2 interphotoreceptor matrix proteoglycan 2
INA internexin neuronal intermediate filament protein, alpha
INHBB inhibin, beta B
INSIG1 insulin induced gene 1
INTS7 integrator complex subunit 7
IQGAP1 IQ motif containing GTPase activating protein 1
ITGB4 integrin, beta 4
ITGB6 integrin, beta 6
KANSL3 KAT8 regulatory NSL complex subunit 3
KBTBD12 kelch repeat and BTB (POZ) domain containing 12
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCTD5 potassium channel tetramerization domain containing 5
KIAA0513 KIAA0513
KIAA1468 KIAA1468
KIF9 kinesin family member 9
KRT20 keratin 20, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LDB1 LIM domain binding 1
LEF1 lymphoid enhancer-binding factor 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIFR leukemia inhibitory factor receptor alpha
LINC00222 long intergenic non-protein coding RNA 222
LINC00251 long intergenic non-protein coding RNA 251
LINC00534 long intergenic non-protein coding RNA 534
LINC00642 long intergenic non-protein coding RNA 642
LINC00896 long intergenic non-protein coding RNA 896
LINC00954 long intergenic non-protein coding RNA 954
LMNA lamin A/C
LOC100130264 uncharacterized LOC100130264
LOC100506071 uncharacterized LOC100506071
LOC100506172
LOC100507577 uncharacterized LOC100507577
LOC646938 TBC1 domain family, member 2B pseudogene
LOC729987 uncharacterized LOC729987
LOXHD1 lipoxygenase homology domains 1
LRP5 low density lipoprotein receptor-related protein 5
LRRC37A2 leucine rich repeat containing 37, member A2
LSM12 LSM12 homolog (S. cerevisiae)
MAGEF1 melanoma antigen family F1
MAP2K3 mitogen-activated protein kinase kinase 3
MCTS1 malignant T cell amplified sequence 1
MDK midkine (neurite growth-promoting factor 2)
MED15 mediator complex subunit 15
MEIS2 Meis homeobox 2
METTL8 methyltransferase like 8
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MFRP membrane frizzled-related protein
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MIR1908 microRNA 1908
MIR206 microRNA 206
MIR30C2 microRNA 30c-2
MIR30E microRNA 30e
MIR365A microRNA 365a
MIR4302 microRNA 4302
MIR4493 microRNA 4493
MIR4654 microRNA 4654
MIR4736 microRNA 4736
MIR4743 microRNA 4743
MIR490 microRNA 490
MIR5004 microRNA 5004
MIR5089 microRNA 5089
MRVI1 murine retrovirus integration site 1 homolog
MT-TA tRNA
MYADML2 myeloid-associated differentiation marker-like 2
MYO16-AS1 MYO16 antisense RNA 1
MYO7A myosin VIIA
MYO9B myosin IXB
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NBEAL2 neurobeachin-like 2
NID2 nidogen 2 (osteonidogen)
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOL12 nucleolar protein 12
NPC1 Niemann-Pick disease, type C1
NPC1L1 NPC1-like 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2F2-AS1 NR2F2 antisense RNA 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
NRK Nik related kinase
NRP2 neuropilin 2
NSD1 nuclear receptor binding SET domain protein 1
NTM neurotrimin
OAZ2 ornithine decarboxylase antizyme 2
OR10AD1 olfactory receptor, family 10, subfamily AD, member 1
OR10V1 olfactory receptor, family 10, subfamily V, member 1
OSGIN1 oxidative stress induced growth inhibitor 1
OSR1 odd-skipped related transciption factor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAPD7 PAP associated domain containing 7
PCBP3 poly(rC) binding protein 3
PCDHGB3 protocadherin gamma subfamily B, 3
PCTP phosphatidylcholine transfer protein
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PEX14 peroxisomal biogenesis factor 14
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGC progastricsin (pepsinogen C)
PHACTR3 phosphatase and actin regulator 3
PHF8 PHD finger protein 8
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOSPHO1 phosphatase, orphan 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLA1A phospholipase A1 member A
PLB1 phospholipase B1
PLEKHM3 pleckstrin homology domain containing, family M, member 3
PLXDC2 plexin domain containing 2
PMVK phosphomevalonate kinase
PNKD paroxysmal nonkinesigenic dyskinesia
POR P450 (cytochrome) oxidoreductase
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRDM6 PR domain containing 6
PRKG1-AS1 PRKG1 antisense RNA 1
PROM2 prominin 2
PRRC2B proline-rich coiled-coil 2B
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRRT3 proline-rich transmembrane protein 3
PRUNE prune exopolyphosphatase
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PTK2B protein tyrosine kinase 2 beta
PVALB parvalbumin
RADIL Ras association and DIL domains
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBSN rabenosyn, RAB effector
RELT RELT tumor necrosis factor receptor
RFC4 replication factor C (activator 1) 4, 37kDa
RGS1 regulator of G-protein signaling 1
RHOQ ras homolog family member Q
RIN2 Ras and Rab interactor 2
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF103 ring finger protein 103
RNF157-AS1 RNF157 antisense RNA 1
RNF165 ring finger protein 165
RNF216-IT1 RNF216 intronic transcript 1
RPIA ribose 5-phosphate isomerase A
RPL11 ribosomal protein L11
RTP1 receptor (chemosensory) transporter protein 1
RXFP3 relaxin/insulin-like family peptide receptor 3
S100A14 S100 calcium binding protein A14
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SDK1 sidekick cell adhesion molecule 1
SDK2 sidekick cell adhesion molecule 2
SEC61G Sec61 gamma subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT9 septin 9
SERINC2 serine incorporator 2
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGMS1 sphingomyelin synthase 1
SGMS2 sphingomyelin synthase 2
SGPP2 sphingosine-1-phosphate phosphatase 2
SIK2 salt-inducible kinase 2
SLC12A8 solute carrier family 12, member 8
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
SLC25A47 solute carrier family 25, member 47
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35E1 solute carrier family 35, member E1
SLC38A3 solute carrier family 38, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAD7 SMAD family member 7
SMO smoothened, frizzled class receptor
SMTN smoothelin
SNN stannin
SNORA68 small nucleolar RNA, H/ACA box 68
SNORD67 small nucleolar RNA, C/D box 67
SNORD93 small nucleolar RNA, C/D box 93
SOD3 superoxide dismutase 3, extracellular
SPAG11A sperm associated antigen 11A
SPAG11B sperm associated antigen 11B
SPAG5 sperm associated antigen 5
SPAG8 sperm associated antigen 8
SPPL3 signal peptide peptidase like 3
SPRR1B small proline-rich protein 1B
STRIP2 striatin interacting protein 2
STYXL1 serine/threonine/tyrosine interacting-like 1
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SYNPO synaptopodin
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAPBPL TAP binding protein-like
TBC1D7 TBC1 domain family, member 7
TBX22 T-box 22
TCAP titin-cap
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCP10 t-complex 10
THAP2 THAP domain containing, apoptosis associated protein 2
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TMC6 transmembrane channel-like 6
TMCO4 transmembrane and coiled-coil domains 4
TMEM117 transmembrane protein 117
TMEM132A transmembrane protein 132A
TMEM171 transmembrane protein 171
TMEM184B transmembrane protein 184B
TMEM233 transmembrane protein 233
TMEM43 transmembrane protein 43
TMEM63C transmembrane protein 63C
TMEM87A transmembrane protein 87A
TMPRSS6 transmembrane protease, serine 6
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNNT2 troponin T type 2 (cardiac)
TPCN2 two pore segment channel 2
TPM1 tropomyosin 1 (alpha)
TPP1 tripeptidyl peptidase I
TRIM62 tripartite motif containing 62
TRIOBP TRIO and F-actin binding protein
TRIP4 thyroid hormone receptor interactor 4
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC8 tetratricopeptide repeat domain 8
TTN titin
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UNC5B-AS1 UNC5B antisense RNA 1
VMP1 vacuole membrane protein 1
VWA5B2 von Willebrand factor A domain containing 5B2
WDR36 WD repeat domain 36
WDR90 WD repeat domain 90
WIPF3 WAS/WASL interacting protein family, member 3
WNT10A wingless-type MMTV integration site family, member 10A
WRAP73 WD repeat containing, antisense to TP73
WWOX WW domain containing oxidoreductase
ZBTB9 zinc finger and BTB domain containing 9
ZMYND11 zinc finger, MYND-type containing 11
ZNF250 zinc finger protein 250
ZNF436-AS1 ZNF436 antisense RNA 1
ZNF518B zinc finger protein 518B
ZNF697 zinc finger protein 697
ZNF804B zinc finger protein 804B
ZYG11A zyg-11 family member A, cell cycle regulator
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1