LTF Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description lactotransferrin|This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 4057)
External Link http://www.ncbi.nlm.nih.gov/gene/4057
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137 interacting proteins for LTF from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AGGF1 angiogenic factor with G patch and FHA domains 1
AMBRA1 autophagy/beclin-1 regulator 1
ANXA1 annexin A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B2M beta-2-microglobulin
BPIFA1 BPI fold containing family A, member 1
BPIFB1 BPI fold containing family B, member 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CBX3 chromobox homolog 3
CD14 CD14 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CEL carboxyl ester lipase
CIZ1 CDKN1A interacting zinc finger protein 1
CKB creatine kinase, brain
CP ceruloplasmin (ferroxidase)
CREB3L2 cAMP responsive element binding protein 3-like 2
CTSG cathepsin G
CTTNBP2NL CTTNBP2 N-terminal like
DCAF7 DDB1 and CUL4 associated factor 7
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA4 defensin, alpha 4, corticostatin
DMBT1 deleted in malignant brain tumors 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DYNLRB1 dynein, light chain, roadblock-type 1
ELANE elastase, neutrophil expressed
EML3 echinoderm microtubule associated protein like 3
ESYT2 extended synaptotagmin-like protein 2
FAM172A family with sequence similarity 172, member A
FBXO30 F-box protein 30
FBXO38 F-box protein 38
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLCCI1 glucocorticoid induced 1
GPHN gephyrin
H2AFJ H2A histone family, member J
HDAC2 histone deacetylase 2
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AH histone cluster 1, H2ah
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H2AC histone cluster 2, H2ac
HIST2H2BF histone cluster 2, H2bf
HIST3H2A histone cluster 3, H2a
HMMR hyaluronan-mediated motility receptor (RHAMM)
IFFO2 intermediate filament family orphan 2
IGHA1 immunoglobulin heavy constant alpha 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGKC immunoglobulin kappa constant
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IKBIP IKBKB interacting protein
ITLN1 intelectin 1 (galactofuranose binding)
KANK1 KN motif and ankyrin repeat domains 1
KANK2 KN motif and ankyrin repeat domains 2
KDM1A lysine (K)-specific demethylase 1A
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
LCN1 lipocalin 1
LRP1 low density lipoprotein receptor-related protein 1
LYZ lysozyme
MAPK12 mitogen-activated protein kinase 12
MAPK15 mitogen-activated protein kinase 15
MASTL microtubule associated serine/threonine kinase-like
MOB4 MOB family member 4, phocein
MORC3 MORC family CW-type zinc finger 3
MPO myeloperoxidase
MTPAP mitochondrial poly(A) polymerase
MUC7 mucin 7, secreted
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEK9 NIMA-related kinase 9
NUCLEOLIN nucleolin multifunctional protein
PDCD10 programmed cell death 10
PFN1 profilin 1
PIGR polymeric immunoglobulin receptor
PIP prolactin-induced protein
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRTN3 proteinase 3
RBM14 RNA binding motif protein 14
RCOR1 REST corepressor 1
RCOR3 REST corepressor 3
SACK1D scaffolding CK1 anchoring protein D
SGK1 serum/glucocorticoid regulated kinase 1
SIRT7 sirtuin 7
SKP1 S-phase kinase-associated protein 1
SPAG5 sperm associated antigen 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STK25 serine/threonine kinase 25
STRIP1 striatin interacting protein 1
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLK1 tousled-like kinase 1
TLK2 tousled-like kinase 2
TP53BP1 tumor protein p53 binding protein 1
TRPS1 trichorhinophalangeal syndrome I
UBC ubiquitin C
WDR34 WD repeat domain 34
WDR60 WD repeat domain 60
WDR81 WD repeat domain 81
WFDC2 WAP four-disulfide core domain 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZMYM2 zinc finger, MYM-type 2
ZMYM3 zinc finger, MYM-type 3
ZMYM4 zinc finger, MYM-type 4
ZNF609 zinc finger protein 609