LTK Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description leukocyte receptor tyrosine kinase|The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 4058)
Similar Terms
Downloads & Tools

Genes

100 substrates of the kinase LTK from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 99.98
CNOT9 CCR4-NOT transcription complex subunit 9 99.96
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 99.94
ZCCHC3 zinc finger, CCHC domain containing 3 99.91
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 99.89
WWP2 WW domain containing E3 ubiquitin protein ligase 2 99.83
PADI2 peptidyl arginine deiminase, type II 99.72
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 99.71
UNG uracil-DNA glycosylase 99.63
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 99.61
KMT5A lysine methyltransferase 5A 99.59
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 99.56
NAV1 neuron navigator 1 99.52
LOC102725035 leukocyte immunoglobulin-like receptor subfamily B member 3 99.5
RABGAP1L RAB GTPase activating protein 1-like 99.43
PTPRB protein tyrosine phosphatase, receptor type, B 99.37
ARHGAP30 Rho GTPase activating protein 30 99.36
ARRDC3 arrestin domain containing 3 99.26
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 99.17
SRCIN1 SRC kinase signaling inhibitor 1 99.105
PTPRA protein tyrosine phosphatase, receptor type, A 99.08
PRPS1 phosphoribosyl pyrophosphate synthetase 1 98.99
RPS10 ribosomal protein S10 98.95
RPS10-NUDT3 RPS10-NUDT3 readthrough 98.95
MKNK1 MAP kinase interacting serine/threonine kinase 1 98.88
CNBD2 cyclic nucleotide binding domain containing 2 98.78
PHLDB3 pleckstrin homology-like domain, family B, member 3 98.71
FCHO1 FCH domain only 1 98.69
UBASH3A ubiquitin associated and SH3 domain containing A 98.64
FBXO9 F-box protein 9 98.62
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 98.56
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 98.51
GCSAML germinal center-associated, signaling and motility-like 98.415
LST1 leukocyte specific transcript 1 98.4
PRPS2 phosphoribosyl pyrophosphate synthetase 2 98.2
COX6C cytochrome c oxidase subunit VIc 98.18
LY6G6F lymphocyte antigen 6 complex, locus G6F 98.14
RGS10 regulator of G-protein signaling 10 98.07
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 98.05
CHD2 chromodomain helicase DNA binding protein 2 97.99
FAF2 Fas associated factor family member 2 97.96
MUC16 mucin 16, cell surface associated 97.94
TWF1 twinfilin actin binding protein 1 97.85
CD300LB CD300 molecule-like family member b 97.81
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 97.79
GREB1 growth regulation by estrogen in breast cancer 1 97.75
DCAF13 DDB1 and CUL4 associated factor 13 97.74
RGS14 regulator of G-protein signaling 14 97.72
PLXDC2 plexin domain containing 2 97.7
RIC1 RAB6A GEF complex partner 1 97.68
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 97.66
DCTN4 dynactin 4 (p62) 97.62
PLCL2 phospholipase C-like 2 97.61
FHIT fragile histidine triad 97.55
FCRL4 Fc receptor-like 4 97.55
UBE2E3 ubiquitin-conjugating enzyme E2E 3 97.55
UBE2E2 ubiquitin-conjugating enzyme E2E 2 97.55
UBE2E1 ubiquitin-conjugating enzyme E2E 1 97.55
RPL8 ribosomal protein L8 97.5
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 97.48
KLC3 kinesin light chain 3 97.35
JAML junction adhesion molecule like 97.31
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 97.22
N4BP3 NEDD4 binding protein 3 97.18
PSME3IP1 proteasome activator subunit 3 interacting protein 1 97.16
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 97.15
ANXA6 annexin A6 97.11
IKZF3 IKAROS family zinc finger 3 (Aiolos) 97.05
RPL36AL ribosomal protein L36a-like 97.02
MPZL1 myelin protein zero-like 1 96.94
PTPRE protein tyrosine phosphatase, receptor type, E 96.93
TRIM25 tripartite motif containing 25 96.91
FCRL6 Fc receptor-like 6 96.89
TRIP11 thyroid hormone receptor interactor 11 96.85
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 96.83
SMG8 SMG8 nonsense mediated mRNA decay factor 96.7
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 96.67
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 96.67
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 96.65
ELP3 elongator acetyltransferase complex subunit 3 96.635
SH2D3C SH2 domain containing 3C 96.56
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 96.53
FKBP5 FK506 binding protein 5 96.46
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 96.45
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 96.45
DPH6 diphthamine biosynthesis 6 96.43
EIF1B eukaryotic translation initiation factor 1B 96.39
EIF1 eukaryotic translation initiation factor 1 96.39
EIF4A3 eukaryotic translation initiation factor 4A3 96.35
RPL10A ribosomal protein L10a 96.3
TEX2 testis expressed 2 96.28
KATNB1 katanin p80 (WD repeat containing) subunit B 1 96.24
CCT8 chaperonin containing TCP1, subunit 8 (theta) 96.21
CLMP CXADR-like membrane protein 96.17
KIF20A kinesin family member 20A 96.06
RIPOR3 RIPOR family member 3 96.0
FAM168A family with sequence similarity 168, member A 95.97
TERB1 telomere repeat binding bouquet formation protein 1 95.93
RPS21 ribosomal protein S21 95.91
SVBP small vasohibin binding protein 95.86