LUMIRACOXIB Gene Set

Dataset	DGIdb Drug Targets 2026
Category	physical interactions
Type	drug
Description	An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. (Chemical Entities of Biological Interest Ontology, CHEBI_73044)
External Link	https://dgidb.org/results?searchType=drug&searchTerms=LUMIRACOXIB
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Genes

6 interacting proteins for the LUMIRACOXIB drug from theDGIdb Drug Targets 2026 dataset.

Symbol	Name	Standardized Value
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	1.03788
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.735167
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.265323
HLA-DRB1	major histocompatibility complex, class II, DR beta 1	0.25571
PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	0.131672
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.0202339