LXF-289 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

281 genes with high or low expression in LXF-289 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.29003
KIF18A kinesin family member 18A 2.15625
TMEM165 transmembrane protein 165 2.14792
ADAM12 ADAM metallopeptidase domain 12 2.14152
TRIM48 tripartite motif containing 48 1.97757
MEOX1 mesenchyme homeobox 1 1.97194
IL11 interleukin 11 1.91308
DNAAF5 dynein, axonemal, assembly factor 5 1.90254
GCLM glutamate-cysteine ligase, modifier subunit 1.88421
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 1.85528
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 1.82348
TKT transketolase 1.8087
TJP1 tight junction protein 1 1.78974
EBNA1BP2 EBNA1 binding protein 2 1.78515
SPDL1 spindle apparatus coiled-coil protein 1 1.77677
ACKR3 atypical chemokine receptor 3 1.76369
UGDH UDP-glucose 6-dehydrogenase 1.72128
ARL4A ADP-ribosylation factor-like 4A 1.70502
ERCC8 excision repair cross-complementation group 8 1.70406
BDNF brain-derived neurotrophic factor 1.69736
NUCLEOLIN nucleolin multifunctional protein 1.65452
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 1.6478
UBE2K ubiquitin-conjugating enzyme E2K 1.60049
ERCC3 excision repair cross-complementation group 3 1.59584
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.59471
OLFM1 olfactomedin 1 1.59335
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 1.58368
SDCCAG3 serologically defined colon cancer antigen 3 1.57993
TDRD1 tudor domain containing 1 1.57778
AFP alpha-fetoprotein 1.57171
COL5A1 collagen, type V, alpha 1 1.56897
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 1.56844
KIAA0368 KIAA0368 1.56623
REXO2 RNA exonuclease 2 1.56167
CUTC cutC copper transporter 1.54739
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.54488
PVRL3 poliovirus receptor-related 3 1.53951
PAPPA2 pappalysin 2 1.5004
HAS1 hyaluronan synthase 1 1.48932
PALLD palladin, cytoskeletal associated protein 1.48823
IL6 interleukin 6 1.48635
AR androgen receptor 1.47984
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.47651
MACF1 microtubule-actin crosslinking factor 1 1.47555
ANKLE2 ankyrin repeat and LEM domain containing 2 1.47442
COL4A1 collagen, type IV, alpha 1 1.47363
DST dystonin 1.47045
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.46676
ACTN4 actinin, alpha 4 1.45947
DPY19L1 dpy-19-like 1 (C. elegans) 1.45836
FOXF2 forkhead box F2 1.44546
NQO2 NAD(P)H dehydrogenase, quinone 2 1.445
TGFB2 transforming growth factor, beta 2 1.44286

low expression

Symbol Name Standardized Value
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -3.53724
SCAMP5 secretory carrier membrane protein 5 -3.48641
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -2.95927
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -2.92709
RNF17 ring finger protein 17 -2.88409
MVK mevalonate kinase -2.87465
GPR19 G protein-coupled receptor 19 -2.84776
HADH hydroxyacyl-CoA dehydrogenase -2.82096
EAF2 ELL associated factor 2 -2.80293
GRM6 glutamate receptor, metabotropic 6 -2.77277
TRA T cell receptor alpha locus -2.67419
NRXN2 neurexin 2 -2.65758
TOR3A torsin family 3, member A -2.60101
VWA5A von Willebrand factor A domain containing 5A -2.58698
TONSL tonsoku-like, DNA repair protein -2.56498
RAE1 ribonucleic acid export 1 -2.55647
FHL5 four and a half LIM domains 5 -2.55001
SLAMF8 SLAM family member 8 -2.49959
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene -2.49134
ZNF85 zinc finger protein 85 -2.48336
GUK1 guanylate kinase 1 -2.45277
PRPF6 pre-mRNA processing factor 6 -2.42133
ACTN2 actinin, alpha 2 -2.31737
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -2.28909
CXCL11 chemokine (C-X-C motif) ligand 11 -2.28671
SH3PXD2A SH3 and PX domains 2A -2.27238
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -2.26855
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 -2.25684
EVI2B ecotropic viral integration site 2B -2.22375
MANBA mannosidase, beta A, lysosomal -2.19003
RASIP1 Ras interacting protein 1 -2.18954
PHKA2 phosphorylase kinase, alpha 2 (liver) -2.18109
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -2.18049
TMEM144 transmembrane protein 144 -2.17203
MAN1C1 mannosidase, alpha, class 1C, member 1 -2.1685
DPF3 D4, zinc and double PHD fingers, family 3 -2.12251
RGS13 regulator of G-protein signaling 13 -2.09417
SYP synaptophysin -2.08974
SERF2 small EDRK-rich factor 2 -2.08598
KLHL3 kelch-like family member 3 -2.08061
INSM1 insulinoma-associated 1 -2.08032
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -2.07981
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -2.06667
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -2.0544
PTPRH protein tyrosine phosphatase, receptor type, H -2.04668
GMPR2 guanosine monophosphate reductase 2 -2.04566
RLN1 relaxin 1 -2.04318
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -2.02521
MTMR10 myotubularin related protein 10 -2.02384
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -2.01205
FGF17 fibroblast growth factor 17 -1.99457
GRIK1 glutamate receptor, ionotropic, kainate 1 -1.99023
DIDO1 death inducer-obliterator 1 -1.98681
SNTA1 syntrophin, alpha 1 -1.98495
SPINK5 serine peptidase inhibitor, Kazal type 5 -1.98258
POFUT1 protein O-fucosyltransferase 1 -1.95507
OR3A3 olfactory receptor, family 3, subfamily A, member 3 -1.95278
CD40 CD40 molecule, TNF receptor superfamily member 5 -1.95231
CD1E CD1e molecule -1.9503
GP2 glycoprotein 2 (zymogen granule membrane) -1.94871
RTEL1 regulator of telomere elongation helicase 1 -1.94279
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -1.94116
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -1.9379
FNDC8 fibronectin type III domain containing 8 -1.93314
GJB5 gap junction protein, beta 5, 31.1kDa -1.92357
USP27X ubiquitin specific peptidase 27, X-linked -1.92196
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -1.91983
PCDHGC3 protocadherin gamma subfamily C, 3 -1.9071
FBLN5 fibulin 5 -1.90447
WNT3 wingless-type MMTV integration site family, member 3 -1.90331
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -1.90065
ATXN8OS ATXN8 opposite strand (non-protein coding) -1.89603
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.87905
JAK3 Janus kinase 3 -1.87614
MED4 mediator complex subunit 4 -1.86368
CALM3 calmodulin 3 (phosphorylase kinase, delta) -1.86303
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -1.86237
RELN reelin -1.8534
PROM1 prominin 1 -1.84129
COLEC12 collectin sub-family member 12 -1.83728
MMP12 matrix metallopeptidase 12 -1.83481
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -1.83475
VASH1 vasohibin 1 -1.82984
BLK BLK proto-oncogene, Src family tyrosine kinase -1.82087
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.81736
DUOX2 dual oxidase 2 -1.80647
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.806
POU1F1 POU class 1 homeobox 1 -1.80019
ETV1 ets variant 1 -1.7845
MUC8 mucin 8 -1.78363
DIAPH3 diaphanous-related formin 3 -1.78337
OR10H3 olfactory receptor, family 10, subfamily H, member 3 -1.78156
FGF4 fibroblast growth factor 4 -1.77705
PIGR polymeric immunoglobulin receptor -1.77438
SACK1E scaffolding CK1 anchoring protein E -1.77367
SPICE1 spindle and centriole associated protein 1 -1.76934
P3H3 prolyl 3-hydroxylase 3 -1.76894
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.75842
CA5B carbonic anhydrase VB, mitochondrial -1.75776
GFRA3 GDNF family receptor alpha 3 -1.757
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -1.75609
CCKBR cholecystokinin B receptor -1.7535
RPN2 ribophorin II -1.75152
LMOD1 leiomodin 1 (smooth muscle) -1.74605
SARDH sarcosine dehydrogenase -1.7432
CLDN8 claudin 8 -1.74274
HMGN2 high mobility group nucleosomal binding domain 2 -1.74091
TM2D1 TM2 domain containing 1 -1.73849
CHAD chondroadherin -1.73161
SDS serine dehydratase -1.72107
IVD isovaleryl-CoA dehydrogenase -1.71866
HLF hepatic leukemia factor -1.71019
ARF1 ADP-ribosylation factor 1 -1.70901
SLC14A2 solute carrier family 14 (urea transporter), member 2 -1.70103
ADCK2 aarF domain containing kinase 2 -1.69363
NPPB natriuretic peptide B -1.69291
GIMAP5 GTPase, IMAP family member 5 -1.69117
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa -1.6887
FKBP10 FK506 binding protein 10, 65 kDa -1.67871
NDOR1 NADPH dependent diflavin oxidoreductase 1 -1.67274
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -1.6714
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -1.67078
TEX13B testis expressed 13B -1.66721
PAH phenylalanine hydroxylase -1.66634
BRSK2 BR serine/threonine kinase 2 -1.66596
NPFFR1 neuropeptide FF receptor 1 -1.66578
AMELX amelogenin, X-linked -1.65876
TXN2 thioredoxin 2 -1.65711
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) -1.64962
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -1.64386
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit -1.63969
ANKRD55 ankyrin repeat domain 55 -1.63858
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -1.63566
GK glycerol kinase -1.62933
RIN1 Ras and Rab interactor 1 -1.62903
PLN phospholamban -1.62755
CASP5 caspase 5, apoptosis-related cysteine peptidase -1.62724
CD52 CD52 molecule -1.62659
PRSS50 protease, serine, 50 -1.6263
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 -1.62505
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -1.62293
TGM3 transglutaminase 3 -1.62114
GUCA1B guanylate cyclase activator 1B (retina) -1.61689
HDAC5 histone deacetylase 5 -1.61584
ZNF835 zinc finger protein 835 -1.61478
GPR143 G protein-coupled receptor 143 -1.60847
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -1.60705
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -1.60564
ANGPT2 angiopoietin 2 -1.60477
CPSF3L cleavage and polyadenylation specific factor 3-like -1.60298
DPT dermatopontin -1.60128
BAIAP3 BAI1-associated protein 3 -1.59183
CCL19 chemokine (C-C motif) ligand 19 -1.58791
SNTG1 syntrophin, gamma 1 -1.5874
MED31 mediator complex subunit 31 -1.5873
ADGRF5 adhesion G protein-coupled receptor F5 -1.58678
PVRIG poliovirus receptor related immunoglobulin domain containing -1.58623
RPE65 retinal pigment epithelium-specific protein 65kDa -1.58501
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -1.58478
GYS1 glycogen synthase 1 (muscle) -1.58307
UNC5C unc-5 homolog C (C. elegans) -1.58197
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene -1.58116
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -1.58075
IFI6 interferon, alpha-inducible protein 6 -1.57626
IL24 interleukin 24 -1.57557
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 -1.57315
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.56681
CSH2 chorionic somatomammotropin hormone 2 -1.54989
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -1.53863
CFAP70 cilia and flagella associated protein 70 -1.53103
ADORA1 adenosine A1 receptor -1.53103
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.52731
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -1.52632
PODNL1 podocan-like 1 -1.52443
KLK1 kallikrein 1 -1.52191
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -1.51594
STK11 serine/threonine kinase 11 -1.51354
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -1.50929
PPCDC phosphopantothenoylcysteine decarboxylase -1.509
ECE2 endothelin converting enzyme 2 -1.50629
NR2F1 nuclear receptor subfamily 2, group F, member 1 -1.49973
C1QB complement component 1, q subcomponent, B chain -1.49711
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -1.49609
POU4F3 POU class 4 homeobox 3 -1.49473
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -1.49401
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -1.49148
ADAM18 ADAM metallopeptidase domain 18 -1.48917
VWF von Willebrand factor -1.48906
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -1.48763
OPRM1 opioid receptor, mu 1 -1.48047
ADGRG3 adhesion G protein-coupled receptor G3 -1.4801
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -1.47886
APLP1 amyloid beta (A4) precursor-like protein 1 -1.47452
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 -1.47307
HDAC6 histone deacetylase 6 -1.47278
GPR27 G protein-coupled receptor 27 -1.47124
KRT4 keratin 4, type II -1.47015
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -1.46803
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -1.46242
CD80 CD80 molecule -1.46134
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 -1.45911
GJB4 gap junction protein, beta 4, 30.3kDa -1.45864
GCM2 glial cells missing homolog 2 (Drosophila) -1.45535
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -1.45474
KRT14 keratin 14, type I -1.45462
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) -1.45325
MATN4 matrilin 4 -1.45324
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -1.44742
ZXDB zinc finger, X-linked, duplicated B -1.44446
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E -1.44228
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 -1.44222
RSC1A1 regulatory solute carrier protein, family 1, member 1 -1.44023
SPTBN4 spectrin, beta, non-erythrocytic 4 -1.43943
BMX BMX non-receptor tyrosine kinase -1.4382
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 -1.4357
OAZ2 ornithine decarboxylase antizyme 2 -1.43388
ADD3 adducin 3 (gamma) -1.43319
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 -1.43256
ITK IL2-inducible T-cell kinase -1.43016
IL2RB interleukin 2 receptor, beta -1.42993
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -1.42894
SOX11 SRY (sex determining region Y)-box 11 -1.42702
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta -1.427
ZNF710 zinc finger protein 710 -1.42043
CSN1S1 casein alpha s1 -1.42022
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 -1.4195
HIST1H4F histone cluster 1, H4f -1.41775
ABHD8 abhydrolase domain containing 8 -1.4159