| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the LY-2584702 (tosylate salt)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.275193 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.202164 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.159161 |
| B2M | beta-2-microglobulin | 0.157089 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.116737 |
| UBC | ubiquitin C | 0.112604 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.111664 |
| TMSB4X | thymosin beta 4, X-linked | 0.101246 |
| APOL1 | apolipoprotein L, 1 | 0.0950464 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0889587 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0866463 |
| LDHA | lactate dehydrogenase A | 0.0853195 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0817438 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0813486 |
| ENO1 | enolase 1, (alpha) | 0.0812368 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0808426 |
| KRT19 | keratin 19, type I | 0.079878 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0772014 |
| TXNIP | thioredoxin interacting protein | 0.0752269 |
| LCN2 | lipocalin 2 | 0.0732014 |
| FTL | ferritin, light polypeptide | 0.0730217 |
| S100A6 | S100 calcium binding protein A6 | 0.0699138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0672032 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0658411 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0648833 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0647386 |
| MT1X | metallothionein 1X | 0.0626923 |
| HMGA1 | high mobility group AT-hook 1 | 0.0622976 |
| VIM | vimentin | 0.062278 |
| LAMB3 | laminin, beta 3 | 0.0622165 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0598588 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0584896 |
| RPLP0 | ribosomal protein, large, P0 | 0.0583515 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.057852 |
| ANXA2 | annexin A2 | 0.0568145 |
| PKM | pyruvate kinase, muscle | 0.0561458 |
| RPL19 | ribosomal protein L19 | 0.0557077 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.055048 |
| HLA-E | major histocompatibility complex, class I, E | 0.0545795 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0540881 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0536365 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0531955 |
| SMAD3 | SMAD family member 3 | 0.0527153 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0511248 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0504155 |
| TGM2 | transglutaminase 2 | 0.0502617 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0500424 |
| PGK1 | phosphoglycerate kinase 1 | 0.049832 |
| RACK1 | receptor for activated C kinase 1 | 0.0494348 |
| HLA-A | major histocompatibility complex, class I, A | 0.0492919 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0491154 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0480313 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.047584 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0475719 |
| RPLP1 | ribosomal protein, large, P1 | 0.0473609 |
| MT2A | metallothionein 2A | 0.0467815 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0462722 |
| SP100 | SP100 nuclear antigen | 0.0461406 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0455152 |
| HDAC9 | histone deacetylase 9 | 0.0454408 |
| ASPH | aspartate beta-hydroxylase | 0.0452492 |
| MT1E | metallothionein 1E | 0.0448235 |
| S100A10 | S100 calcium binding protein A10 | 0.0446341 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0430236 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0415236 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0407338 |
| EREG | epiregulin | 0.0401576 |
| RPL23 | ribosomal protein L23 | 0.0401336 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0397101 |
| RNF213 | ring finger protein 213 | 0.0395608 |
| FAM13A | family with sequence similarity 13, member A | 0.0394228 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0391757 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0391494 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0391304 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.038639 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0386102 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0385974 |
| EPCAM | epithelial cell adhesion molecule | 0.0384939 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.038283 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0381281 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0379956 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0369996 |
| OPTN | optineurin | 0.0368639 |
| ARRDC3 | arrestin domain containing 3 | 0.0367924 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0367714 |
| IL6ST | interleukin 6 signal transducer | 0.0364535 |
| CD2AP | CD2-associated protein | 0.0363518 |
| RPS8 | ribosomal protein S8 | 0.0363445 |
| RPL34 | ribosomal protein L34 | 0.0358857 |
| PTMA | prothymosin, alpha | 0.0354676 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0345017 |
| TAGLN2 | transgelin 2 | 0.0343519 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0343008 |
| FAM107B | family with sequence similarity 107, member B | 0.0342528 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0339983 |
| SFTPA2 | surfactant protein A2 | 0.0338395 |
| DSTN | destrin (actin depolymerizing factor) | 0.0337758 |
| RPS3 | ribosomal protein S3 | 0.0337758 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0334864 |
| RIOK3 | RIO kinase 3 | 0.0334116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.046897 |
| NCKAP5 | NCK-associated protein 5 | -0.0375397 |
| PLAT | plasminogen activator, tissue | -0.0360954 |
| RPS29 | ribosomal protein S29 | -0.0352578 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0318699 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0300745 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0286653 |
| FLNB | filamin B, beta | -0.0271718 |
| HMGA2 | high mobility group AT-hook 2 | -0.0265798 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0242566 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0208355 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0207352 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0198678 |
| RPL31 | ribosomal protein L31 | -0.019748 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0196755 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.018776 |
| NABP1 | nucleic acid binding protein 1 | -0.0183866 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180827 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0180511 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0179564 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0176007 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0173476 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.016856 |
| RPL37A | ribosomal protein L37a | -0.0165864 |
| PADI1 | peptidyl arginine deiminase, type I | -0.0163533 |
| DST | dystonin | -0.0161807 |
| EGR1 | early growth response 1 | -0.01564 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0155889 |
| RPL36A | ribosomal protein L36a | -0.0154617 |
| CLDN4 | claudin 4 | -0.0153287 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0148312 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0147454 |
| ADAM8 | ADAM metallopeptidase domain 8 | -0.0145467 |
| ITGB4 | integrin, beta 4 | -0.0144162 |
| RPL38 | ribosomal protein L38 | -0.0144108 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0142097 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0139459 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0139305 |
| FMNL2 | formin-like 2 | -0.0138978 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0138564 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0138503 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0137267 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0133576 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.013297 |
| GOLGA8A | golgin A8 family, member A | -0.0130861 |
| RPL36 | ribosomal protein L36 | -0.0127289 |
| AFDN | afadin, adherens junction formation factor | -0.0126443 |
| RHOB | ras homolog family member B | -0.0125315 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.0124898 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.012427 |
| FBXO34 | F-box protein 34 | -0.01238 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0122459 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0121115 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0119814 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0118392 |
| MCU | mitochondrial calcium uniporter | -0.0115955 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0114253 |
| MUC4 | mucin 4, cell surface associated | -0.011353 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0113288 |
| PLS3 | plastin 3 | -0.0113144 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0113128 |
| RPS23 | ribosomal protein S23 | -0.011308 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0112337 |
| RFLNA | refilin A | -0.0112052 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0111204 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0111187 |
| KRT86 | keratin 86, type II | -0.0111017 |
| PARD3 | par-3 family cell polarity regulator | -0.01094 |
| PLCB4 | phospholipase C, beta 4 | -0.0109096 |
| MNMIP1 | manchette microtubule inner protein 1 | -0.010907 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0109023 |
| CFAP73 | cilia and flagella associated protein 73 | -0.0108674 |
| SDC1 | syndecan 1 | -0.010835 |
| ARHGAP23 | Rho GTPase activating protein 23 | -0.0108237 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0108066 |
| CFAP20DC | CFAP20 domain containing | -0.010726 |
| PLEC | plectin | -0.0104132 |
| UTRN | utrophin | -0.0103583 |
| S100P | S100 calcium binding protein P | -0.010358 |
| FA2H | fatty acid 2-hydroxylase | -0.0103556 |
| IER5 | immediate early response 5 | -0.0103181 |
| NBEAL1 | neurobeachin-like 1 | -0.0100717 |
| CMIP | c-Maf inducing protein | -0.00999293 |
| TNS4 | tensin 4 | -0.00998205 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.00991786 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00989156 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00986157 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.00982126 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00968471 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.00968101 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.00963916 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.00963565 |
| INTS6 | integrator complex subunit 6 | -0.00962158 |
| CDK13 | cyclin-dependent kinase 13 | -0.00962059 |
| RASA2 | RAS p21 protein activator 2 | -0.00955663 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00953341 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.00948541 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00947487 |
| SPAG9 | sperm associated antigen 9 | -0.00946965 |
| KCNK6 | potassium channel, two pore domain subfamily K, member 6 | -0.0094694 |
