| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.249775 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.206576 |
| NDRG1 | N-myc downstream regulated 1 | 0.0673084 |
| ASPH | aspartate beta-hydroxylase | 0.0664808 |
| KYNU | kynureninase | 0.0584947 |
| SMAD3 | SMAD family member 3 | 0.0557204 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.055467 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0541519 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0517263 |
| HDAC9 | histone deacetylase 9 | 0.0489879 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0487124 |
| MSN | moesin | 0.0452429 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0448757 |
| STC1 | stanniocalcin 1 | 0.0444747 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0423057 |
| FAM13A | family with sequence similarity 13, member A | 0.0413222 |
| LDHA | lactate dehydrogenase A | 0.0406613 |
| MT2A | metallothionein 2A | 0.0376947 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0376141 |
| TXNIP | thioredoxin interacting protein | 0.036763 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0367179 |
| MCL1 | myeloid cell leukemia 1 | 0.0359804 |
| ARRDC3 | arrestin domain containing 3 | 0.0356941 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0340364 |
| CLTC | clathrin, heavy chain (Hc) | 0.0324558 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321733 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0319761 |
| DTNA | dystrobrevin, alpha | 0.0317243 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0313085 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0307857 |
| UBC | ubiquitin C | 0.0306803 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0306495 |
| HELZ | helicase with zinc finger | 0.0299429 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0293696 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0292634 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0288828 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.028662 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0286423 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0286244 |
| VMP1 | vacuole membrane protein 1 | 0.0285698 |
| RPS12 | ribosomal protein S12 | 0.0277251 |
| FTL | ferritin, light polypeptide | 0.0277211 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0274563 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.027431 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0267709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0262397 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0258874 |
| FLNA | filamin A, alpha | 0.0257498 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0256363 |
| C1S | complement component 1, s subcomponent | 0.0249587 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0248491 |
| LRRC59 | leucine rich repeat containing 59 | 0.0248038 |
| ADM | adrenomedullin | 0.0248025 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0247677 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0247367 |
| RPL28 | ribosomal protein L28 | 0.0245885 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0244951 |
| RPL7 | ribosomal protein L7 | 0.0244822 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0241194 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0240539 |
| ATP13A3 | ATPase type 13A3 | 0.0238757 |
| RPL3 | ribosomal protein L3 | 0.0237581 |
| APP | amyloid beta (A4) precursor protein | 0.0234248 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0233415 |
| TLE4 | transducin-like enhancer of split 4 | 0.0231526 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0231007 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0230951 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0229846 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0225783 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0223288 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0222945 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0222602 |
| RBMX | RNA binding motif protein, X-linked | 0.0222342 |
| WWOX | WW domain containing oxidoreductase | 0.021917 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0217314 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0216833 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0215963 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0213671 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.021348 |
| AUTS2 | autism susceptibility candidate 2 | 0.0212327 |
| CALU | calumenin | 0.0210692 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0210277 |
| SON | SON DNA binding protein | 0.0209571 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.020833 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0206824 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0206346 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0205662 |
| PCM1 | pericentriolar material 1 | 0.020182 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0200388 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0199967 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0199953 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0199895 |
| GPHN | gephyrin | 0.0199593 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0198297 |
| RPL27A | ribosomal protein L27a | 0.0197753 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.019541 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0194273 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0192144 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0192092 |
| H3-3B | H3.3 histone B | 0.01919 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.285931 |
| FN1 | fibronectin 1 | -0.21675 |
| TMSB10 | thymosin beta 10 | -0.197136 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.172649 |
| VIM | vimentin | -0.169073 |
| TPM4 | tropomyosin 4 | -0.102838 |
| PTMA | prothymosin, alpha | -0.0865543 |
| HLA-B | major histocompatibility complex, class I, B | -0.0809387 |
| CANX | calnexin | -0.069714 |
| AHNAK | AHNAK nucleoprotein | -0.0662433 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0630021 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0594968 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0580066 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0574843 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0562385 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0538288 |
| GNAS | GNAS complex locus | -0.0527899 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0495425 |
| VCL | vinculin | -0.0486168 |
| LOX | lysyl oxidase | -0.0476794 |
| POTEF | POTE ankyrin domain family, member F | -0.0468393 |
| PGK1 | phosphoglycerate kinase 1 | -0.0462471 |
| NAV1 | neuron navigator 1 | -0.0459569 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0447716 |
| MAP4 | microtubule-associated protein 4 | -0.0443329 |
| RPL35A | ribosomal protein L35a | -0.0440076 |
| IGF2 | insulin-like growth factor 2 | -0.0435406 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0430531 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.043014 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0414291 |
| STK17A | serine/threonine kinase 17a | -0.0410441 |
| PCNX4 | pecanex 4 | -0.0407537 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0402656 |
| CALR | calreticulin | -0.0400942 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0398882 |
| ENO1 | enolase 1, (alpha) | -0.0391138 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0389383 |
| CALD1 | caldesmon 1 | -0.0386371 |
| EGFR | epidermal growth factor receptor | -0.0383415 |
| ZNF804A | zinc finger protein 804A | -0.0380633 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0375297 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0372511 |
| OSMR | oncostatin M receptor | -0.0371327 |
| TMSB4X | thymosin beta 4, X-linked | -0.0370445 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0358157 |
| RTN4 | reticulon 4 | -0.0357354 |
| PXDN | peroxidasin | -0.0354275 |
| HIP1 | huntingtin interacting protein 1 | -0.0350884 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0350128 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034825 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0346119 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0337395 |
| TMEM123 | transmembrane protein 123 | -0.033312 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0326499 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0323042 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0319755 |
| CD44 | CD44 molecule (Indian blood group) | -0.0318488 |
| NAV3 | neuron navigator 3 | -0.0318176 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0317876 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0298933 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0298773 |
| TNS3 | tensin 3 | -0.0295186 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293979 |
| VEGFA | vascular endothelial growth factor A | -0.0292775 |
| TNNC1 | troponin C type 1 (slow) | -0.0291446 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.0280506 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0279464 |
| SERF2 | small EDRK-rich factor 2 | -0.0277883 |
| CDK13 | cyclin-dependent kinase 13 | -0.0275252 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0272066 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.02705 |
| RRBP1 | ribosome binding protein 1 | -0.0269968 |
| CBX3 | chromobox homolog 3 | -0.026275 |
| ACTG1 | actin gamma 1 | -0.0262739 |
| SDC4 | syndecan 4 | -0.0262337 |
| SBF2 | SET binding factor 2 | -0.0258044 |
| HMGB1 | high mobility group box 1 | -0.0256279 |
| TMEM165 | transmembrane protein 165 | -0.0256234 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0256166 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0253745 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0253241 |
| AAK1 | AP2 associated kinase 1 | -0.0252912 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0252152 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0248575 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.024707 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.024621 |
| CENPF | centromere protein F, 350/400kDa | -0.0245748 |
| EHBP1 | EH domain binding protein 1 | -0.0245314 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0244208 |
| AHR | aryl hydrocarbon receptor | -0.0242861 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0242765 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0240685 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0236025 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0234591 |
| MORF4L2 | mortality factor 4 like 2 | -0.0231919 |
| TUBB | tubulin, beta class I | -0.0231604 |
| EMP3 | epithelial membrane protein 3 | -0.0230732 |
| CAVIN1 | caveolae associated protein 1 | -0.0227547 |
| IL7R | interleukin 7 receptor | -0.0227511 |
| HLA-A | major histocompatibility complex, class I, A | -0.0225813 |
