| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.151475 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.131715 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0873375 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0681407 |
| SMAD3 | SMAD family member 3 | 0.0660125 |
| WWC1 | WW and C2 domain containing 1 | 0.059337 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0568103 |
| B2M | beta-2-microglobulin | 0.0547146 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0527936 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0510012 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0498101 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0485661 |
| SNX9 | sorting nexin 9 | 0.0457586 |
| ZNF292 | zinc finger protein 292 | 0.0457031 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0455215 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0442058 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.04344 |
| PCBP2 | poly(rC) binding protein 2 | 0.0432662 |
| UBC | ubiquitin C | 0.0422088 |
| FTL | ferritin, light polypeptide | 0.0389602 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0365689 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0364489 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0363345 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0362909 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0360743 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0352418 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0349436 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0344694 |
| HELZ | helicase with zinc finger | 0.0344177 |
| FLNA | filamin A, alpha | 0.0339046 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0336107 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0332579 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0328748 |
| RPL3 | ribosomal protein L3 | 0.0323944 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0320379 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0312581 |
| GOLGA4 | golgin A4 | 0.0299565 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0297734 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.029691 |
| RPS12 | ribosomal protein S12 | 0.0294564 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0293451 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0293149 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0292305 |
| AFDN | afadin, adherens junction formation factor | 0.0292296 |
| CCNL1 | cyclin L1 | 0.0291285 |
| SPAG9 | sperm associated antigen 9 | 0.0286097 |
| SLTM | SAFB-like, transcription modulator | 0.0283819 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.028207 |
| RPL7 | ribosomal protein L7 | 0.0280175 |
| RPL21 | ribosomal protein L21 | 0.0278147 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0276495 |
| PKM | pyruvate kinase, muscle | 0.0270913 |
| SLMAP | sarcolemma associated protein | 0.0267436 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0265591 |
| APP | amyloid beta (A4) precursor protein | 0.0264497 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0264096 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0263669 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0262277 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0261051 |
| VMP1 | vacuole membrane protein 1 | 0.0260746 |
| TUSC3 | tumor suppressor candidate 3 | 0.0260354 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0259519 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0258224 |
| SGMS2 | sphingomyelin synthase 2 | 0.0253577 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0252515 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.024981 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0249712 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0246635 |
| RPL11 | ribosomal protein L11 | 0.0246104 |
| RND3 | Rho family GTPase 3 | 0.0244945 |
| ZNF638 | zinc finger protein 638 | 0.0243654 |
| ECT2 | epithelial cell transforming 2 | 0.024218 |
| BRD2 | bromodomain containing 2 | 0.0239317 |
| RPL23 | ribosomal protein L23 | 0.0239255 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0236957 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0236801 |
| MED13 | mediator complex subunit 13 | 0.0236492 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0235307 |
| SET | SET nuclear proto-oncogene | 0.0234342 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0231977 |
| RPL7A | ribosomal protein L7a | 0.0231662 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.022831 |
| TJP1 | tight junction protein 1 | 0.0227125 |
| DIAPH1 | diaphanous-related formin 1 | 0.0224583 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0221032 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0220817 |
| RPS5 | ribosomal protein S5 | 0.0218973 |
| ANXA11 | annexin A11 | 0.0217896 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0214989 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0213647 |
| SIK3 | SIK family kinase 3 | 0.0211157 |
| RNF145 | ring finger protein 145 | 0.0210742 |
| ITGB8 | integrin, beta 8 | 0.021049 |
| RPS2 | ribosomal protein S2 | 0.0207634 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0205993 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0202118 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0200015 |
| FOSL1 | FOS-like antigen 1 | 0.0199971 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.019834 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.019751 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.33991 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.189305 |
| TMSB10 | thymosin beta 10 | -0.141537 |
| PTMA | prothymosin, alpha | -0.121429 |
| AHNAK | AHNAK nucleoprotein | -0.117314 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0824092 |
| TPM4 | tropomyosin 4 | -0.0800616 |
| ASPH | aspartate beta-hydroxylase | -0.0756845 |
| CCND1 | cyclin D1 | -0.0712821 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0659128 |
| CANX | calnexin | -0.0655235 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0622241 |
| NDRG1 | N-myc downstream regulated 1 | -0.0566204 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0553871 |
| MAP4 | microtubule-associated protein 4 | -0.0547754 |
| HMGA2 | high mobility group AT-hook 2 | -0.054528 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0530803 |
| ENO1 | enolase 1, (alpha) | -0.0509516 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0483807 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.047336 |
| LAMB3 | laminin, beta 3 | -0.0469159 |
| VCAN | versican | -0.0466854 |
| VCL | vinculin | -0.0463102 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0462594 |
| RPL35A | ribosomal protein L35a | -0.044449 |
| EGFR | epidermal growth factor receptor | -0.0434567 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0422377 |
| CLDN1 | claudin 1 | -0.0421204 |
| CD44 | CD44 molecule (Indian blood group) | -0.0419293 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0382743 |
| PCED1B | PC-esterase domain containing 1B | -0.0381572 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0380631 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0379634 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0374128 |
| ATG7 | autophagy related 7 | -0.0370945 |
| MT2A | metallothionein 2A | -0.0369282 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0368783 |
| TUBB | tubulin, beta class I | -0.0368076 |
| HMGA1 | high mobility group AT-hook 1 | -0.03629 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0359004 |
| HMGB1 | high mobility group box 1 | -0.0357716 |
| ANXA2 | annexin A2 | -0.0357519 |
| RPL34 | ribosomal protein L34 | -0.0343724 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0340787 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0337433 |
| HDLBP | high density lipoprotein binding protein | -0.0335907 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334613 |
| LAMA4 | laminin, alpha 4 | -0.0327924 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0326535 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0322982 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0317369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0311478 |
| KRT19 | keratin 19, type I | -0.0309695 |
| RAD51B | RAD51 paralog B | -0.0307749 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0307369 |
| RPS24 | ribosomal protein S24 | -0.0304476 |
| GNAS | GNAS complex locus | -0.030419 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0302425 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0299972 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0299139 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0297976 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0293128 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0287767 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0280337 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0276912 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0276771 |
| EXOC4 | exocyst complex component 4 | -0.0276621 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0272481 |
| EHBP1 | EH domain binding protein 1 | -0.0272371 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0269904 |
| WDR45B | WD repeat domain 45B | -0.0268331 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0266725 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0266596 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265234 |
| CALR | calreticulin | -0.026353 |
| TMSB4X | thymosin beta 4, X-linked | -0.0260743 |
| DOCK4 | dedicator of cytokinesis 4 | -0.025916 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0258366 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0251597 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0249999 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.024364 |
| SEPTIN10 | septin 10 | -0.0239338 |
| RPL38 | ribosomal protein L38 | -0.0238853 |
| DENND1A | DENN/MADD domain containing 1A | -0.0229718 |
| S100A9 | S100 calcium binding protein A9 | -0.0227568 |
| MKI67 | marker of proliferation Ki-67 | -0.0227305 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0226692 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0224509 |
| HKDC1 | hexokinase domain containing 1 | -0.0223591 |
| KRT18 | keratin 18, type I | -0.0223353 |
| ITGA6 | integrin, alpha 6 | -0.0217734 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0217415 |
| S100A6 | S100 calcium binding protein A6 | -0.0215843 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0215485 |
| STC2 | stanniocalcin 2 | -0.021488 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0211121 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0209397 |
| DEK | DEK proto-oncogene | -0.0208688 |
| IER3 | immediate early response 3 | -0.0206372 |
| RPS6 | ribosomal protein S6 | -0.0202815 |
