| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.113187 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.106918 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.104239 |
| CLU | clusterin | 0.0791546 |
| MYOF | myoferlin | 0.0770286 |
| CD44 | CD44 molecule (Indian blood group) | 0.0685052 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0596761 |
| SMAD3 | SMAD family member 3 | 0.0554245 |
| MSN | moesin | 0.0553456 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0528853 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0523597 |
| VCL | vinculin | 0.0516066 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0507876 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0477012 |
| BCL2L1 | BCL2-like 1 | 0.0467293 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0460432 |
| H1-0 | H1.0 linker histone | 0.0458252 |
| TGM2 | transglutaminase 2 | 0.044547 |
| RPS8 | ribosomal protein S8 | 0.0436704 |
| KRT17 | keratin 17, type I | 0.0433734 |
| FOXO1 | forkhead box O1 | 0.0428479 |
| POTEF | POTE ankyrin domain family, member F | 0.042412 |
| LDHA | lactate dehydrogenase A | 0.0423356 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.042076 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0408869 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0404732 |
| ANKRD33B | ankyrin repeat domain 33B | 0.039203 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0384555 |
| NRG1 | neuregulin 1 | 0.0378674 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0371846 |
| PTK2 | protein tyrosine kinase 2 | 0.0366758 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0364941 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0364824 |
| PRELID2 | PRELI domain containing 2 | 0.0358641 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0339588 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0338159 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0335867 |
| SEPTIN9 | septin 9 | 0.0333475 |
| RPLP2 | ribosomal protein, large, P2 | 0.0330161 |
| TXNIP | thioredoxin interacting protein | 0.0327732 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0320757 |
| RPS25 | ribosomal protein S25 | 0.0320226 |
| UBC | ubiquitin C | 0.0318496 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0315712 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0315331 |
| RPL21 | ribosomal protein L21 | 0.0309868 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0301856 |
| RPS21 | ribosomal protein S21 | 0.0288807 |
| MCL1 | myeloid cell leukemia 1 | 0.0288017 |
| LAMA5 | laminin, alpha 5 | 0.0287433 |
| RPS12 | ribosomal protein S12 | 0.0284979 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0283538 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0282622 |
| CAPRIN2 | caprin family member 2 | 0.0282184 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0280293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0280086 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0278307 |
| ITGA6 | integrin, alpha 6 | 0.0278091 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0277335 |
| ANXA1 | annexin A1 | 0.0276403 |
| TPX2 | TPX2, microtubule-associated | 0.0276129 |
| S100A10 | S100 calcium binding protein A10 | 0.0275219 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0272413 |
| DSTN | destrin (actin depolymerizing factor) | 0.027083 |
| JMJD1C | jumonji domain containing 1C | 0.0266637 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0266521 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0264901 |
| ARRDC3 | arrestin domain containing 3 | 0.0262486 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0261034 |
| EFHD2 | EF-hand domain family, member D2 | 0.0260569 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0259773 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0255933 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0255868 |
| FNIP1 | folliculin interacting protein 1 | 0.0254584 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0253979 |
| RPS13 | ribosomal protein S13 | 0.0253448 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251978 |
| KRT6A | keratin 6A, type II | 0.0250934 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0250929 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0249768 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.024838 |
| VMP1 | vacuole membrane protein 1 | 0.0246982 |
| RBM39 | RNA binding motif protein 39 | 0.0246527 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.024611 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244238 |
| EMP1 | epithelial membrane protein 1 | 0.0244171 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0243755 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0242778 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0240903 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0240759 |
| RPL37 | ribosomal protein L37 | 0.0239067 |
| SLTM | SAFB-like, transcription modulator | 0.023847 |
| SERTAD2 | SERTA domain containing 2 | 0.023832 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0237095 |
| TLN1 | talin 1 | 0.0234971 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0233406 |
| TPI1 | triosephosphate isomerase 1 | 0.0232938 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0232859 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0232508 |
| INTS6 | integrator complex subunit 6 | 0.0230524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.233879 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.131076 |
| RAI14 | retinoic acid induced 14 | -0.0610493 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0597583 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0574355 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0565878 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0489463 |
| MTSS1 | metastasis suppressor 1 | -0.0475805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0473649 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0457049 |
| PTMA | prothymosin, alpha | -0.0405507 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0380198 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0357115 |
| SULF1 | sulfatase 1 | -0.0323477 |
| IGF2 | insulin-like growth factor 2 | -0.032088 |
| HLA-B | major histocompatibility complex, class I, B | -0.0317069 |
| SULF2 | sulfatase 2 | -0.0312159 |
| TMSB4X | thymosin beta 4, X-linked | -0.030534 |
| CALB1 | calbindin 1, 28kDa | -0.0299457 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.02816 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0279025 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271786 |
| RPL34 | ribosomal protein L34 | -0.0270125 |
| THBD | thrombomodulin | -0.0259782 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0250275 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0248996 |
| LAMC2 | laminin, gamma 2 | -0.0245971 |
| RIGI | RNA sensor RIG-I | -0.0236772 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.023549 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0235233 |
| CAVIN1 | caveolae associated protein 1 | -0.0226786 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0226348 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0225403 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0217402 |
| FBXO11 | F-box protein 11 | -0.0214399 |
| HLA-E | major histocompatibility complex, class I, E | -0.0213657 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0206793 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0205494 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0201875 |
| UTRN | utrophin | -0.0194761 |
| LAMB3 | laminin, beta 3 | -0.019261 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0191477 |
| SQSTM1 | sequestosome 1 | -0.0188992 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0188399 |
| ENOSF1 | enolase superfamily member 1 | -0.0187169 |
| AHNAK | AHNAK nucleoprotein | -0.0185054 |
| RPL35A | ribosomal protein L35a | -0.0185035 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0178592 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0178083 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0177933 |
| GNAS | GNAS complex locus | -0.0175696 |
| LMO7 | LIM domain 7 | -0.0175189 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.017484 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0173046 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0170918 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0165793 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0162289 |
| CUX1 | cut-like homeobox 1 | -0.0158847 |
| DOK5 | docking protein 5 | -0.0158305 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.015799 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0157115 |
| ZFHX3 | zinc finger homeobox 3 | -0.0154453 |
| PIR | pirin (iron-binding nuclear protein) | -0.0153046 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0153022 |
| PGK1 | phosphoglycerate kinase 1 | -0.0151923 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0149643 |
| MEF2A | myocyte enhancer factor 2A | -0.0149413 |
| HMGB1 | high mobility group box 1 | -0.0146653 |
| STC1 | stanniocalcin 1 | -0.0145316 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.0144627 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0144032 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0143637 |
| PLTP | phospholipid transfer protein | -0.0142294 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0141879 |
| SMYD3 | SET and MYND domain containing 3 | -0.0141749 |
| IL1B | interleukin 1, beta | -0.0141409 |
| RASA3 | RAS p21 protein activator 3 | -0.0141185 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0139892 |
| RPLP1 | ribosomal protein, large, P1 | -0.0139691 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0139446 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0136021 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0134812 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.013325 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0132661 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0132298 |
| PLIN2 | perilipin 2 | -0.0131783 |
| FOXC1 | forkhead box C1 | -0.013121 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0130477 |
| LAMA4 | laminin, alpha 4 | -0.0129244 |
| TRIM56 | tripartite motif containing 56 | -0.0127154 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0126858 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0126527 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.0126045 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0125852 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.012563 |
| MT1X | metallothionein 1X | -0.0122462 |
| FDPS | farnesyl diphosphate synthase | -0.0122105 |
| NANOS3 | nanos homolog 3 (Drosophila) | -0.0121869 |
| NCF2 | neutrophil cytosolic factor 2 | -0.0121726 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0121652 |
