| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the LY-2584702 (tosylate salt)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.177519 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.119372 |
| VIM | vimentin | 0.0842788 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0635533 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0588104 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0569985 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0423096 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0368929 |
| AHNAK | AHNAK nucleoprotein | 0.0343708 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336043 |
| MCL1 | myeloid cell leukemia 1 | 0.0318316 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0302559 |
| FRMD6 | FERM domain containing 6 | 0.0292829 |
| TXNIP | thioredoxin interacting protein | 0.0292294 |
| CD44 | CD44 molecule (Indian blood group) | 0.0291116 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.028934 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0272817 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270176 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0269098 |
| LDHA | lactate dehydrogenase A | 0.0267395 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0246295 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0241526 |
| CALD1 | caldesmon 1 | 0.0237932 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0236174 |
| HSPA8 | heat shock 70kDa protein 8 | 0.022643 |
| KYNU | kynureninase | 0.0224694 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219215 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0198242 |
| FN1 | fibronectin 1 | 0.0197944 |
| CTSB | cathepsin B | 0.0197031 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0195835 |
| RPL7 | ribosomal protein L7 | 0.0190715 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0187048 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0185599 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0182505 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0182027 |
| JUN | jun proto-oncogene | 0.0176921 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0175832 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.017487 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.017411 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0171569 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0169064 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0167367 |
| MSN | moesin | 0.0165307 |
| TPM3 | tropomyosin 3 | 0.0165115 |
| EMP1 | epithelial membrane protein 1 | 0.0161378 |
| DST | dystonin | 0.016117 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.016089 |
| SBF2 | SET binding factor 2 | 0.0160881 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.015993 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0158493 |
| UBC | ubiquitin C | 0.0154666 |
| STC1 | stanniocalcin 1 | 0.0154058 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0154053 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0153814 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0153643 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0149573 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0148184 |
| ANXA2 | annexin A2 | 0.0148039 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.014773 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0145246 |
| CCN2 | cellular communication network factor 2 | 0.014425 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0144098 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0143971 |
| ACTN1 | actinin, alpha 1 | 0.0143928 |
| CD163L1 | CD163 molecule-like 1 | 0.0143364 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0141299 |
| VCL | vinculin | 0.0138094 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0137078 |
| JMJD1C | jumonji domain containing 1C | 0.0134853 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.01308 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0130418 |
| SERINC1 | serine incorporator 1 | 0.0130371 |
| H1-0 | H1.0 linker histone | 0.0129254 |
| PLK2 | polo-like kinase 2 | 0.0126194 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0125751 |
| SMAD3 | SMAD family member 3 | 0.0125211 |
| ERBIN | erbb2 interacting protein | 0.0124976 |
| RPL3 | ribosomal protein L3 | 0.0124719 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0124057 |
| RTN4 | reticulon 4 | 0.0123057 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0122136 |
| RPL4 | ribosomal protein L4 | 0.0121986 |
| ZNF217 | zinc finger protein 217 | 0.0121534 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.012064 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0119674 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0119663 |
| RPS7 | ribosomal protein S7 | 0.0116434 |
| APP | amyloid beta (A4) precursor protein | 0.0115896 |
| RAD21 | RAD21 homolog (S. pombe) | 0.011585 |
| ITGA6 | integrin, alpha 6 | 0.0115344 |
| TLN1 | talin 1 | 0.0112909 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0112538 |
| TPM4 | tropomyosin 4 | 0.0111932 |
| MYO10 | myosin X | 0.0111171 |
| TNNC1 | troponin C type 1 (slow) | 0.0110348 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0109804 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0109563 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0109132 |
| PKM | pyruvate kinase, muscle | 0.0109033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0642998 |
| LSAMP | limbic system-associated membrane protein | -0.0531941 |
| TMSB10 | thymosin beta 10 | -0.0457306 |
| DTNA | dystrobrevin, alpha | -0.0426338 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0408355 |
| MT2A | metallothionein 2A | -0.0383853 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0290333 |
| CDH13 | cadherin 13 | -0.0268556 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0250985 |
| RPL35A | ribosomal protein L35a | -0.0250719 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0238893 |
| EFNA5 | ephrin-A5 | -0.02332 |
| PTK2 | protein tyrosine kinase 2 | -0.022164 |
| GPC6 | glypican 6 | -0.0210689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0207163 |
| GOLGA4 | golgin A4 | -0.0201381 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0201098 |
| RPLP1 | ribosomal protein, large, P1 | -0.0185413 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0184042 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0174558 |
| PFN1 | profilin 1 | -0.0171119 |
| MSR1 | macrophage scavenger receptor 1 | -0.016483 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0155211 |
| ZNF804A | zinc finger protein 804A | -0.0155203 |
| RPLP2 | ribosomal protein, large, P2 | -0.0152479 |
| RPL5 | ribosomal protein L5 | -0.0150361 |
| DGKI | diacylglycerol kinase, iota | -0.0144712 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0143034 |
| RPS13 | ribosomal protein S13 | -0.0139404 |
| FAM162A | family with sequence similarity 162, member A | -0.0131386 |
| RPL36 | ribosomal protein L36 | -0.013129 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0131176 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0130471 |
| RPL32 | ribosomal protein L32 | -0.0125658 |
| POTEF | POTE ankyrin domain family, member F | -0.0123917 |
| GPHN | gephyrin | -0.0123222 |
| KIAA1549L | KIAA1549-like | -0.0119062 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0118053 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0114649 |
| RPL9 | ribosomal protein L9 | -0.011359 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0108815 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0108081 |
| KIAA1217 | KIAA1217 | -0.0107336 |
| SON | SON DNA binding protein | -0.0107058 |
| RPL34 | ribosomal protein L34 | -0.0106731 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0106434 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0103371 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0102241 |
| RPS19 | ribosomal protein S19 | -0.0101854 |
| RBM25 | RNA binding motif protein 25 | -0.0100438 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0100353 |
| RPL28 | ribosomal protein L28 | -0.00999273 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.00996219 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.00990672 |
| RPS21 | ribosomal protein S21 | -0.00960633 |
| RFX7 | regulatory factor X, 7 | -0.00956402 |
| MT1X | metallothionein 1X | -0.00950413 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00943491 |
| LMNA | lamin A/C | -0.00940686 |
| TENM2 | teneurin transmembrane protein 2 | -0.00939587 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.00936451 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00935557 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.009284 |
| THOC2 | THO complex 2 | -0.00912622 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00908149 |
| RPL8 | ribosomal protein L8 | -0.00907581 |
| RPS23 | ribosomal protein S23 | -0.00904452 |
| RPL18 | ribosomal protein L18 | -0.00881386 |
| FNIP1 | folliculin interacting protein 1 | -0.00866229 |
| SMAP1 | small ArfGAP 1 | -0.00849767 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00844871 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.00824289 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00820605 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00815611 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0081442 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.00807249 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00803178 |
| GNAS | GNAS complex locus | -0.00789183 |
| TMEM263 | transmembrane protein 263 | -0.00788927 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00782107 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00780796 |
| NTM | neurotrimin | -0.00765252 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.00749548 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.00742485 |
| RUNX1 | runt-related transcription factor 1 | -0.00726954 |
| MTDH | metadherin | -0.00723046 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00722519 |
| HM13 | histocompatibility (minor) 13 | -0.00720889 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.00718055 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00716995 |
| RPL27 | ribosomal protein L27 | -0.00713258 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00711078 |
| PCDH9 | protocadherin 9 | -0.00706811 |
| DIAPH3 | diaphanous-related formin 3 | -0.00706519 |
| TCERG1 | transcription elongation regulator 1 | -0.00702139 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0069558 |
| RPL12 | ribosomal protein L12 | -0.00692729 |
| RPL35 | ribosomal protein L35 | -0.00691185 |
| EP400 | E1A binding protein p400 | -0.00689512 |
| RPS4X | ribosomal protein S4, X-linked | -0.00685432 |
