| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.473898 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.159323 |
| FTL | ferritin, light polypeptide | 0.118069 |
| RPS8 | ribosomal protein S8 | 0.0842116 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0789696 |
| RPS6 | ribosomal protein S6 | 0.0677757 |
| LDHA | lactate dehydrogenase A | 0.0650335 |
| HMGA1 | high mobility group AT-hook 1 | 0.0585951 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0564288 |
| MT2A | metallothionein 2A | 0.0546917 |
| RPL12 | ribosomal protein L12 | 0.0519421 |
| TXNIP | thioredoxin interacting protein | 0.0476338 |
| B2M | beta-2-microglobulin | 0.0452198 |
| JMJD1C | jumonji domain containing 1C | 0.0412595 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0372199 |
| GOLGA4 | golgin A4 | 0.0367031 |
| TPI1 | triosephosphate isomerase 1 | 0.0362672 |
| RPLP0 | ribosomal protein, large, P0 | 0.0360189 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0341743 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0319396 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0314394 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0309635 |
| SEC24A | SEC24 family member A | 0.0302684 |
| POTEF | POTE ankyrin domain family, member F | 0.0295863 |
| SON | SON DNA binding protein | 0.0292802 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0292042 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0290299 |
| SLK | STE20-like kinase | 0.0288626 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0288474 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0273798 |
| RPS12 | ribosomal protein S12 | 0.0271957 |
| MSN | moesin | 0.0270141 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0269742 |
| PGK1 | phosphoglycerate kinase 1 | 0.0268747 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0267071 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0265808 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0241454 |
| RACK1 | receptor for activated C kinase 1 | 0.0238633 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0235546 |
| PFN1 | profilin 1 | 0.0235222 |
| BRD2 | bromodomain containing 2 | 0.0233508 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0232747 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0226082 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0221403 |
| LOXL2 | lysyl oxidase-like 2 | 0.0221257 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0218418 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0218069 |
| RPS2 | ribosomal protein S2 | 0.0217185 |
| ASTN2 | astrotactin 2 | 0.0212124 |
| SPAG9 | sperm associated antigen 9 | 0.0211868 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0210899 |
| RPL37 | ribosomal protein L37 | 0.0208179 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0207398 |
| RPL7A | ribosomal protein L7a | 0.0206746 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0202907 |
| SFTPA2 | surfactant protein A2 | 0.0202081 |
| RPS5 | ribosomal protein S5 | 0.0201861 |
| WDR43 | WD repeat domain 43 | 0.0200191 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0200142 |
| SETD5 | SET domain containing 5 | 0.019769 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0197115 |
| RPL18 | ribosomal protein L18 | 0.0196867 |
| CCNL1 | cyclin L1 | 0.0194952 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0193699 |
| MYADM | myeloid-associated differentiation marker | 0.0193523 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0193231 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0192894 |
| S100A10 | S100 calcium binding protein A10 | 0.0191779 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0191238 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0190223 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0189749 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187777 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 0.0186573 |
| PCM1 | pericentriolar material 1 | 0.0182288 |
| MORF4L2 | mortality factor 4 like 2 | 0.0181783 |
| RPL11 | ribosomal protein L11 | 0.0181389 |
| YEATS2 | YEATS domain containing 2 | 0.0178944 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0177484 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0177251 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0172539 |
| ZNF638 | zinc finger protein 638 | 0.0171776 |
| UBXN4 | UBX domain protein 4 | 0.0171382 |
| RPL28 | ribosomal protein L28 | 0.017076 |
| RLF | rearranged L-myc fusion | 0.0170624 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.016848 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0168475 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0167867 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0167354 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0166723 |
| RPS13 | ribosomal protein S13 | 0.0166051 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0161886 |
| RPS27 | ribosomal protein S27 | 0.0160574 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0160426 |
| RPL21 | ribosomal protein L21 | 0.0160305 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0160071 |
| RPL10A | ribosomal protein L10a | 0.0160022 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0159989 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0159387 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0159034 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0156414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.133063 |
| TP63 | tumor protein p63 | -0.120248 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.111321 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.108875 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0966782 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0942862 |
| PTMA | prothymosin, alpha | -0.0817544 |
| AHNAK | AHNAK nucleoprotein | -0.0790633 |
| DST | dystonin | -0.0786086 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0785362 |
| TMSB10 | thymosin beta 10 | -0.0751256 |
| CADM2 | cell adhesion molecule 2 | -0.0688556 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0683667 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0678431 |
| RPS27A | ribosomal protein S27a | -0.0644371 |
| EHBP1 | EH domain binding protein 1 | -0.0619927 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0590559 |
| APP | amyloid beta (A4) precursor protein | -0.0554204 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0511811 |
| UBC | ubiquitin C | -0.0506323 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0477952 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0451544 |
| VCL | vinculin | -0.0448535 |
| RIGI | RNA sensor RIG-I | -0.0438506 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0427633 |
| EXOC4 | exocyst complex component 4 | -0.0426978 |
| JUN | jun proto-oncogene | -0.0400821 |
| CMIP | c-Maf inducing protein | -0.0400765 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0385023 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.038428 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0381888 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0375209 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0373059 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0355009 |
| PRELID2 | PRELI domain containing 2 | -0.035471 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.034136 |
| TNS3 | tensin 3 | -0.0340808 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0335783 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0316485 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0315573 |
| MYOF | myoferlin | -0.031234 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0310694 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0303415 |
| DNER | delta/notch-like EGF repeat containing | -0.0302039 |
| CANX | calnexin | -0.0301768 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0299238 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.029779 |
| SMYD3 | SET and MYND domain containing 3 | -0.0296224 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.02907 |
| EFNA5 | ephrin-A5 | -0.0287293 |
| ENO1 | enolase 1, (alpha) | -0.0286445 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0283603 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0282361 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0281292 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0277423 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0272667 |
| SDC4 | syndecan 4 | -0.026803 |
| PLSCR1 | phospholipid scramblase 1 | -0.0261395 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0258522 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0254696 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0252952 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0252123 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0251209 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0245726 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0243033 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0242046 |
| STK17A | serine/threonine kinase 17a | -0.0240309 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0237834 |
| VMP1 | vacuole membrane protein 1 | -0.0236447 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0234832 |
| SQSTM1 | sequestosome 1 | -0.023238 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0229622 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.022657 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0221258 |
| ETV6 | ets variant 6 | -0.0221135 |
| PARD3 | par-3 family cell polarity regulator | -0.0221009 |
| FLNB | filamin B, beta | -0.0218776 |
| RPS29 | ribosomal protein S29 | -0.0216954 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0216814 |
| TRIM56 | tripartite motif containing 56 | -0.0216322 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0211177 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0210146 |
| SP100 | SP100 nuclear antigen | -0.0206007 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0204866 |
| FMNL2 | formin-like 2 | -0.0196375 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0195244 |
| HMGB2 | high mobility group box 2 | -0.0194773 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0194502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0194322 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0192422 |
| AEBP2 | AE binding protein 2 | -0.0190597 |
| DENND1A | DENN/MADD domain containing 1A | -0.0188107 |
| CUX1 | cut-like homeobox 1 | -0.0186686 |
| FUS | FUS RNA binding protein | -0.0186596 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0184032 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0183837 |
| WDR27 | WD repeat domain 27 | -0.0182259 |
| GLG1 | golgi glycoprotein 1 | -0.0179612 |
| FOXP1 | forkhead box P1 | -0.0176946 |
| FBXO11 | F-box protein 11 | -0.0175277 |
