| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.125852 |
| VIM | vimentin | 0.125339 |
| HDAC9 | histone deacetylase 9 | 0.0951918 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0854151 |
| RPS16 | ribosomal protein S16 | 0.0794388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0793334 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0722056 |
| RPL37 | ribosomal protein L37 | 0.0674046 |
| RPS12 | ribosomal protein S12 | 0.0671514 |
| ZNF292 | zinc finger protein 292 | 0.0663346 |
| GPC3 | glypican 3 | 0.0636825 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0634127 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0602219 |
| RPL7 | ribosomal protein L7 | 0.0600801 |
| ACTG1 | actin gamma 1 | 0.0599906 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0566933 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0558772 |
| RPL5 | ribosomal protein L5 | 0.0555378 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.054915 |
| PEG10 | paternally expressed 10 | 0.0547697 |
| RPS19 | ribosomal protein S19 | 0.0541826 |
| ENAH | enabled homolog (Drosophila) | 0.0500015 |
| COL1A2 | collagen, type I, alpha 2 | 0.0498738 |
| ENO1 | enolase 1, (alpha) | 0.0494936 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0489048 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0478279 |
| NEBL | nebulette | 0.0461414 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0454801 |
| USP25 | ubiquitin specific peptidase 25 | 0.0453962 |
| UPP1 | uridine phosphorylase 1 | 0.0452386 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0442295 |
| RPS6 | ribosomal protein S6 | 0.0438444 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0435226 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0433177 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0427303 |
| NCAM2 | neural cell adhesion molecule 2 | 0.042289 |
| RPL37A | ribosomal protein L37a | 0.0410183 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0409818 |
| APP | amyloid beta (A4) precursor protein | 0.0409698 |
| TMSB10 | thymosin beta 10 | 0.0406023 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0400592 |
| ITGAV | integrin, alpha V | 0.039443 |
| RPLP2 | ribosomal protein, large, P2 | 0.0393462 |
| RPS23 | ribosomal protein S23 | 0.0385367 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0382118 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0381246 |
| RPS27A | ribosomal protein S27a | 0.0379925 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0376628 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0375032 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.037399 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0370695 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0368183 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0363988 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.035662 |
| RBM20 | RNA binding motif protein 20 | 0.0356152 |
| MED13L | mediator complex subunit 13-like | 0.0354011 |
| RPS3 | ribosomal protein S3 | 0.035262 |
| RPL7A | ribosomal protein L7a | 0.0352308 |
| MEF2C | myocyte enhancer factor 2C | 0.0351581 |
| RPS29 | ribosomal protein S29 | 0.0349396 |
| RPL23 | ribosomal protein L23 | 0.0349171 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0346945 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0346357 |
| RPL26 | ribosomal protein L26 | 0.0341438 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.032986 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0328613 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0328565 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0328434 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0327041 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0322514 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.032111 |
| PGK1 | phosphoglycerate kinase 1 | 0.0320333 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0320155 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.031937 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0319005 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0316606 |
| SYT1 | synaptotagmin I | 0.0313118 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0310433 |
| RPS17 | ribosomal protein S17 | 0.0309199 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0308034 |
| RPL36A | ribosomal protein L36a | 0.0305498 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0304956 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0303488 |
| CDH19 | cadherin 19, type 2 | 0.0302941 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0301853 |
| SQSTM1 | sequestosome 1 | 0.0295842 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0295722 |
| VMP1 | vacuole membrane protein 1 | 0.0291541 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0289291 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0285751 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0285326 |
| ANXA1 | annexin A1 | 0.028382 |
| CLTC | clathrin, heavy chain (Hc) | 0.0281276 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0277941 |
| ANK2 | ankyrin 2, neuronal | 0.0276172 |
| BRD2 | bromodomain containing 2 | 0.0275324 |
| RPS27 | ribosomal protein S27 | 0.0274929 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0270203 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0268798 |
| ACTN4 | actinin, alpha 4 | 0.0267433 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0792084 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0564067 |
| AHNAK | AHNAK nucleoprotein | -0.0559069 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0481388 |
| HMGB1 | high mobility group box 1 | -0.0452514 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0427666 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0421227 |
| CBX3 | chromobox homolog 3 | -0.040463 |
| RTN4 | reticulon 4 | -0.0398824 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0386561 |
| SPAG9 | sperm associated antigen 9 | -0.0378824 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0372805 |
| PTMA | prothymosin, alpha | -0.0372364 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0360805 |
| SGO2 | shugoshin 2 | -0.0351914 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0333642 |
| MATR3 | matrin 3 | -0.0326154 |
| PCDH9 | protocadherin 9 | -0.0311387 |
| EMP1 | epithelial membrane protein 1 | -0.0307147 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.030164 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0299013 |
| CENPF | centromere protein F, 350/400kDa | -0.0296383 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0289701 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0279707 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0277895 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0276608 |
| CENPE | centromere protein E, 312kDa | -0.0276606 |
| H1-0 | H1.0 linker histone | -0.0274313 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0270178 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0261069 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0260529 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0258301 |
| BBX | bobby sox homolog (Drosophila) | -0.0255193 |
| TFG | TRK-fused gene | -0.024936 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0245602 |
| BRDT | bromodomain, testis-specific | -0.0243982 |
| MKI67 | marker of proliferation Ki-67 | -0.0243609 |
| DPPA4 | developmental pluripotency associated 4 | -0.0240226 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0239374 |
| GNAS | GNAS complex locus | -0.0239326 |
| COPA | coatomer protein complex, subunit alpha | -0.0239143 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0238109 |
| TUBB | tubulin, beta class I | -0.0236167 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0235863 |
| MYO9B | myosin IXB | -0.0235103 |
| PRR16 | proline rich 16 | -0.0234888 |
| MORF4L2 | mortality factor 4 like 2 | -0.0231117 |
| DPYD | dihydropyrimidine dehydrogenase | -0.023081 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.023054 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0229954 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0228905 |
| RNF145 | ring finger protein 145 | -0.0227782 |
| PFN1 | profilin 1 | -0.0227691 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0224169 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0223262 |
| DEPDC1 | DEP domain containing 1 | -0.0222894 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0221693 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0221432 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0221302 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0220936 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0220323 |
| ANKRD17 | ankyrin repeat domain 17 | -0.021976 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0219621 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0216543 |
| RYK | receptor-like tyrosine kinase | -0.0216115 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0214684 |
| NDRG1 | N-myc downstream regulated 1 | -0.0214414 |
| THOC2 | THO complex 2 | -0.0214112 |
| FAM13A | family with sequence similarity 13, member A | -0.0213864 |
| PHF6 | PHD finger protein 6 | -0.0213583 |
| RBM33 | RNA binding motif protein 33 | -0.0213192 |
| KIAA1958 | KIAA1958 | -0.0212889 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0210178 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0208636 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0206545 |
| PRR11 | proline rich 11 | -0.0205633 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0205309 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0203878 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.020297 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0202495 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0200502 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0200263 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0199841 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0198656 |
| HELLS | helicase, lymphoid-specific | -0.0198284 |
| NUCB2 | nucleobindin 2 | -0.0198163 |
| ANXA2 | annexin A2 | -0.0197598 |
| ZNF207 | zinc finger protein 207 | -0.0197259 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0196467 |
| COL3A1 | collagen, type III, alpha 1 | -0.0195944 |
| ANLN | anillin, actin binding protein | -0.0194538 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0194293 |
| RHOA | ras homolog family member A | -0.0193021 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0191301 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0190998 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0190624 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0190622 |
| ZNF385D | zinc finger protein 385D | -0.0190331 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0189898 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0186202 |
