| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0977632 |
| SMAD3 | SMAD family member 3 | 0.0976671 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0964928 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0889024 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0836968 |
| JMJD1C | jumonji domain containing 1C | 0.0638723 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0629913 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0626898 |
| MED13L | mediator complex subunit 13-like | 0.0546875 |
| PTK2 | protein tyrosine kinase 2 | 0.0542423 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0495522 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0487601 |
| ASPH | aspartate beta-hydroxylase | 0.0480253 |
| DST | dystonin | 0.0468887 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0455801 |
| ACTN4 | actinin, alpha 4 | 0.0452825 |
| RPS16 | ribosomal protein S16 | 0.0444531 |
| SBF2 | SET binding factor 2 | 0.041731 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0417193 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.041382 |
| USP34 | ubiquitin specific peptidase 34 | 0.0400575 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0386723 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0385395 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0368753 |
| SEPTIN9 | septin 9 | 0.0363334 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0354822 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0351387 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0351089 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0344091 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0342878 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0337546 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0332362 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0331444 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0330692 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.032849 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0325425 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0323531 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0323236 |
| UBC | ubiquitin C | 0.0322929 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0318691 |
| ZNF292 | zinc finger protein 292 | 0.0315404 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0311242 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0310902 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0309566 |
| NF1 | neurofibromin 1 | 0.0309509 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0309016 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0306532 |
| RPS12 | ribosomal protein S12 | 0.0306068 |
| THOC2 | THO complex 2 | 0.030395 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0300832 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0298196 |
| ZNF638 | zinc finger protein 638 | 0.0296906 |
| ATXN1 | ataxin 1 | 0.0296164 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0295791 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0294488 |
| PCBP2 | poly(rC) binding protein 2 | 0.0290136 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0288672 |
| VMP1 | vacuole membrane protein 1 | 0.0287573 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0282804 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281507 |
| AFAP1 | actin filament associated protein 1 | 0.0280306 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0279776 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0278347 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0275738 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.02733 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0272472 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.027159 |
| PHF14 | PHD finger protein 14 | 0.026939 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268943 |
| MSN | moesin | 0.0268192 |
| MT2A | metallothionein 2A | 0.0264078 |
| ARRDC3 | arrestin domain containing 3 | 0.0263338 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0262523 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0262274 |
| BRD2 | bromodomain containing 2 | 0.0261006 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.025853 |
| SMYD3 | SET and MYND domain containing 3 | 0.0254197 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0254153 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0249793 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0249467 |
| FMNL2 | formin-like 2 | 0.0247775 |
| ATP13A3 | ATPase type 13A3 | 0.0247392 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0246756 |
| GPHN | gephyrin | 0.0246499 |
| RPS3 | ribosomal protein S3 | 0.024643 |
| ZNF780B | zinc finger protein 780B | 0.0245681 |
| NUP98 | nucleoporin 98kDa | 0.0245175 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0244527 |
| IPO7 | importin 7 | 0.024345 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0243301 |
| WDR43 | WD repeat domain 43 | 0.024264 |
| SATB2 | SATB homeobox 2 | 0.0242214 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0240524 |
| NAV2 | neuron navigator 2 | 0.0239193 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0238989 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.023688 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0236153 |
| PTEN | phosphatase and tensin homolog | 0.0233748 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.023269 |
| ITGAV | integrin, alpha V | 0.0232489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.358286 |
| VIM | vimentin | -0.224328 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.21694 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.203149 |
| PTMA | prothymosin, alpha | -0.180236 |
| AHNAK | AHNAK nucleoprotein | -0.0848525 |
| TMSB10 | thymosin beta 10 | -0.0744881 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0674662 |
| CANX | calnexin | -0.0666847 |
| RPL35A | ribosomal protein L35a | -0.051357 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0468096 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0448183 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.043963 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0405747 |
| CTSD | cathepsin D | -0.0393309 |
| TMEM123 | transmembrane protein 123 | -0.0334142 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0314826 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.028875 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282587 |
| EGR1 | early growth response 1 | -0.0279133 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0269647 |
| MAP1B | microtubule-associated protein 1B | -0.0265068 |
| GNAS | GNAS complex locus | -0.0262936 |
| RPLP1 | ribosomal protein, large, P1 | -0.026182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.025771 |
| S100A6 | S100 calcium binding protein A6 | -0.0250276 |
| RPS24 | ribosomal protein S24 | -0.024741 |
| RPL38 | ribosomal protein L38 | -0.0245813 |
| CALR | calreticulin | -0.0244582 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0232042 |
| HDLBP | high density lipoprotein binding protein | -0.021082 |
| TPM4 | tropomyosin 4 | -0.0208071 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0207891 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.020769 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0205626 |
| RPL34 | ribosomal protein L34 | -0.0203939 |
| RPL37A | ribosomal protein L37a | -0.020059 |
| RPL4 | ribosomal protein L4 | -0.0189438 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0180835 |
| HMGB1 | high mobility group box 1 | -0.0176649 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.017089 |
| HMGA1 | high mobility group AT-hook 1 | -0.0169736 |
| H1-0 | H1.0 linker histone | -0.0169507 |
| CAVIN1 | caveolae associated protein 1 | -0.0166752 |
| HLA-B | major histocompatibility complex, class I, B | -0.0166392 |
| PLIN2 | perilipin 2 | -0.0161496 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.016047 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0159944 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0158613 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0157341 |
| RPS27A | ribosomal protein S27a | -0.0149188 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0147631 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.014629 |
| ACTG1 | actin gamma 1 | -0.0145943 |
| FBXO27 | F-box protein 27 | -0.0144828 |
| NUCB2 | nucleobindin 2 | -0.0144349 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.014277 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0141142 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0140917 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0140551 |
| CDCP1 | CUB domain containing protein 1 | -0.0138823 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.01386 |
| PARK7 | parkinson protein 7 | -0.0137964 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.0137291 |
| MAP4 | microtubule-associated protein 4 | -0.0136793 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0136127 |
| TMEM263 | transmembrane protein 263 | -0.0135861 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0133444 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0129694 |
| RAD21 | RAD21 homolog (S. pombe) | -0.012932 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0128495 |
| HYOU1 | hypoxia up-regulated 1 | -0.0128275 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0127905 |
| RPL27A | ribosomal protein L27a | -0.0126932 |
| RPS28 | ribosomal protein S28 | -0.0126309 |
| S100A11 | S100 calcium binding protein A11 | -0.0125094 |
| WDR45B | WD repeat domain 45B | -0.0118413 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0118395 |
| HLA-A | major histocompatibility complex, class I, A | -0.0118311 |
| IER3 | immediate early response 3 | -0.0118182 |
| RPL6 | ribosomal protein L6 | -0.0117345 |
| ARCN1 | archain 1 | -0.0116392 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0116128 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0116128 |
| CENPF | centromere protein F, 350/400kDa | -0.0115349 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0115042 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0113749 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0113633 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0111914 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0111013 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0110878 |
| MCL1 | myeloid cell leukemia 1 | -0.0110611 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0110315 |
| TUBB | tubulin, beta class I | -0.0109564 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0107963 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0107226 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0106599 |
| SQSTM1 | sequestosome 1 | -0.0105217 |
| HM13 | histocompatibility (minor) 13 | -0.0104602 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0104115 |
