| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.153093 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.103394 |
| TXNIP | thioredoxin interacting protein | 0.0999646 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0799504 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0680749 |
| LDHA | lactate dehydrogenase A | 0.0615143 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.057174 |
| SMAD3 | SMAD family member 3 | 0.0537692 |
| BRD2 | bromodomain containing 2 | 0.0503536 |
| B2M | beta-2-microglobulin | 0.0500932 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0486735 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0464868 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0455519 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446068 |
| CCNL1 | cyclin L1 | 0.043571 |
| MCL1 | myeloid cell leukemia 1 | 0.0425789 |
| INTS6 | integrator complex subunit 6 | 0.042569 |
| ARRDC3 | arrestin domain containing 3 | 0.0422603 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0421402 |
| VMP1 | vacuole membrane protein 1 | 0.042119 |
| UBC | ubiquitin C | 0.0411529 |
| MYO5B | myosin VB | 0.0391189 |
| TGM2 | transglutaminase 2 | 0.0389988 |
| NDRG1 | N-myc downstream regulated 1 | 0.0388785 |
| NAV2 | neuron navigator 2 | 0.0377677 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0374256 |
| DSPP | dentin sialophosphoprotein | 0.0356033 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0348923 |
| G0S2 | G0/G1 switch 2 | 0.0338968 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0337242 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0333387 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0333213 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0333138 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0331868 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.032951 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0324624 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0322824 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0320209 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0317451 |
| PCBP2 | poly(rC) binding protein 2 | 0.0309727 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0309615 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296021 |
| ATF3 | activating transcription factor 3 | 0.0293865 |
| RPS12 | ribosomal protein S12 | 0.0276943 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0272662 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0271428 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.027087 |
| SLTM | SAFB-like, transcription modulator | 0.0265016 |
| ANO6 | anoctamin 6 | 0.0261709 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.026006 |
| SIK3 | SIK family kinase 3 | 0.0259805 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259474 |
| TJP1 | tight junction protein 1 | 0.0257798 |
| RPL21 | ribosomal protein L21 | 0.0253984 |
| RPL3 | ribosomal protein L3 | 0.0251624 |
| KRT17 | keratin 17, type I | 0.0250103 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0247503 |
| TPI1 | triosephosphate isomerase 1 | 0.0242143 |
| OPTN | optineurin | 0.0241372 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0239498 |
| WWC1 | WW and C2 domain containing 1 | 0.0239075 |
| GPHN | gephyrin | 0.0236153 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0236092 |
| IL6ST | interleukin 6 signal transducer | 0.0231736 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.023096 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0228587 |
| CLDN4 | claudin 4 | 0.0227909 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0227025 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0222697 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0222422 |
| YBX3 | Y box binding protein 3 | 0.022242 |
| LRRC59 | leucine rich repeat containing 59 | 0.0222253 |
| MSN | moesin | 0.0221828 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0220657 |
| MED13 | mediator complex subunit 13 | 0.0217715 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0215366 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0215242 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0215102 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0213169 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0211372 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0209151 |
| DIAPH1 | diaphanous-related formin 1 | 0.0205744 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0205562 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0204524 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0202286 |
| GOLGA4 | golgin A4 | 0.0200985 |
| TAPBP | TAP binding protein (tapasin) | 0.0200427 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0198886 |
| PKM | pyruvate kinase, muscle | 0.0198306 |
| AREG | amphiregulin | 0.0198162 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0197801 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0197629 |
| FOSL1 | FOS-like antigen 1 | 0.0196795 |
| ADM | adrenomedullin | 0.0195254 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0194748 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0194743 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0192648 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.019102 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.019068 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0190579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.177543 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.148884 |
| FN1 | fibronectin 1 | -0.127198 |
| LMO7 | LIM domain 7 | -0.12704 |
| TPM4 | tropomyosin 4 | -0.107212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101912 |
| CANX | calnexin | -0.0988503 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0969448 |
| TMSB4X | thymosin beta 4, X-linked | -0.0940957 |
| TMSB10 | thymosin beta 10 | -0.0860729 |
| AHNAK | AHNAK nucleoprotein | -0.0820214 |
| VCL | vinculin | -0.0799946 |
| RPL35A | ribosomal protein L35a | -0.0705222 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0695097 |
| ANXA2 | annexin A2 | -0.0661507 |
| SYT14 | synaptotagmin XIV | -0.0660503 |
| ACTG1 | actin gamma 1 | -0.0646226 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0625595 |
| DSG2 | desmoglein 2 | -0.0610711 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0610421 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0589899 |
| CD2AP | CD2-associated protein | -0.0586917 |
| MUC4 | mucin 4, cell surface associated | -0.0583239 |
| LAMA4 | laminin, alpha 4 | -0.0578201 |
| HLA-B | major histocompatibility complex, class I, B | -0.0566987 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0544795 |
| HLA-E | major histocompatibility complex, class I, E | -0.0540136 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0506719 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0505947 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.049789 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0481261 |
| RPS24 | ribosomal protein S24 | -0.0462238 |
| RPLP1 | ribosomal protein, large, P1 | -0.0449461 |
| TMEM123 | transmembrane protein 123 | -0.0447552 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0443217 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0436409 |
| RPL34 | ribosomal protein L34 | -0.0410359 |
| S100A6 | S100 calcium binding protein A6 | -0.0410223 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0406603 |
| EHBP1 | EH domain binding protein 1 | -0.0406304 |
| GNAS | GNAS complex locus | -0.0397607 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0397254 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0370474 |
| SULF2 | sulfatase 2 | -0.0370299 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0367373 |
| KPNB1 | karyopherin (importin) beta 1 | -0.036494 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0363189 |
| HMGB1 | high mobility group box 1 | -0.0362967 |
| CD44 | CD44 molecule (Indian blood group) | -0.0361397 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0350499 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0347667 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0345354 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0342907 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0341515 |
| RPL38 | ribosomal protein L38 | -0.0333226 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.032837 |
| RPS27A | ribosomal protein S27a | -0.0325409 |
| MMP7 | matrix metallopeptidase 7 | -0.0321076 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0317537 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0315876 |
| MYO1E | myosin IE | -0.0313316 |
| ACTN4 | actinin, alpha 4 | -0.0313229 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0308243 |
| HLA-C | major histocompatibility complex, class I, C | -0.030818 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0306585 |
| LAMB3 | laminin, beta 3 | -0.0305503 |
| MUC20 | mucin 20, cell surface associated | -0.0305469 |
| ANLN | anillin, actin binding protein | -0.0302379 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0301307 |
| MECOM | MDS1 and EVI1 complex locus | -0.0300408 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0299803 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0295937 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.029401 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0292175 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0290873 |
| THRB | thyroid hormone receptor, beta | -0.0287479 |
| ASPH | aspartate beta-hydroxylase | -0.0286013 |
| WDR45B | WD repeat domain 45B | -0.0285182 |
| MYOF | myoferlin | -0.0284767 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0284154 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0282566 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0281662 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0280631 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0278803 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0276465 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0276253 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.027238 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0267879 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0264835 |
| CAVIN1 | caveolae associated protein 1 | -0.0263949 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0261927 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0257601 |
| RPL37A | ribosomal protein L37a | -0.025736 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0255577 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0252651 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | -0.0251953 |
| ZNF217 | zinc finger protein 217 | -0.0251649 |
| EGFR | epidermal growth factor receptor | -0.0251429 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0249568 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0249294 |
