| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the LY-2584702 (tosylate salt)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.228978 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.095424 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0840727 |
| LDHA | lactate dehydrogenase A | 0.0831558 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0734568 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0536356 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0534824 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0492149 |
| CD44 | CD44 molecule (Indian blood group) | 0.0450089 |
| INTS6 | integrator complex subunit 6 | 0.0446472 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0437477 |
| SQSTM1 | sequestosome 1 | 0.0434883 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0428874 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0427421 |
| PKM | pyruvate kinase, muscle | 0.0422715 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0409335 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0378922 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0377966 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.036383 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0335354 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0334907 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0333092 |
| RIGI | RNA sensor RIG-I | 0.033232 |
| GOLGA4 | golgin A4 | 0.0321693 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0313107 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0312305 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0311211 |
| S100A10 | S100 calcium binding protein A10 | 0.0309992 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0309157 |
| SMAD3 | SMAD family member 3 | 0.0308824 |
| GOLGB1 | golgin B1 | 0.0307269 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0301626 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0298076 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0294481 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.029413 |
| DSTN | destrin (actin depolymerizing factor) | 0.0291919 |
| VIM | vimentin | 0.0289718 |
| TPI1 | triosephosphate isomerase 1 | 0.0287783 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0282621 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0281024 |
| H3-3B | H3.3 histone B | 0.0280771 |
| ANXA2 | annexin A2 | 0.0280523 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0279228 |
| ANO6 | anoctamin 6 | 0.0277752 |
| HLA-A | major histocompatibility complex, class I, A | 0.0274776 |
| ADM | adrenomedullin | 0.0272907 |
| ANXA1 | annexin A1 | 0.0271622 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0270091 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0270069 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0268137 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0263217 |
| BRD2 | bromodomain containing 2 | 0.0258546 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.025737 |
| SON | SON DNA binding protein | 0.0247687 |
| ANGPTL4 | angiopoietin-like 4 | 0.0245824 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0245046 |
| DST | dystonin | 0.0242859 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.0242136 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0241034 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0238688 |
| USP34 | ubiquitin specific peptidase 34 | 0.0237076 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0236833 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0233556 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0232856 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0228948 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0227987 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0227739 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0225548 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0220816 |
| DENND4A | DENN/MADD domain containing 4A | 0.0220246 |
| JMJD1C | jumonji domain containing 1C | 0.0216602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0216134 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0213046 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0211154 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0209153 |
| FTL | ferritin, light polypeptide | 0.0204026 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0203532 |
| SIK2 | salt-inducible kinase 2 | 0.0203171 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0202926 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0199323 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0198154 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0196205 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0196149 |
| PHF3 | PHD finger protein 3 | 0.019565 |
| BBX | bobby sox homolog (Drosophila) | 0.0195315 |
| EGR1 | early growth response 1 | 0.01949 |
| PRKCA | protein kinase C, alpha | 0.0194359 |
| CAPRIN2 | caprin family member 2 | 0.0193585 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0192993 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0192733 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0189443 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0188783 |
| KLF10 | Kruppel-like factor 10 | 0.0188421 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.018829 |
| RPL32 | ribosomal protein L32 | 0.0186265 |
| RPL30 | ribosomal protein L30 | 0.0184822 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0180798 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0180655 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0180347 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0179564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0325426 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0272701 |
| PTMA | prothymosin, alpha | -0.0250037 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0238078 |
| TPM4 | tropomyosin 4 | -0.0237813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0228438 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0227588 |
| POTEF | POTE ankyrin domain family, member F | -0.0222135 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0220889 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.022019 |
| FN1 | fibronectin 1 | -0.0199813 |
| CENPF | centromere protein F, 350/400kDa | -0.0192566 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0191785 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0189494 |
| MAP1B | microtubule-associated protein 1B | -0.0184301 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0182203 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0181334 |
| TPX2 | TPX2, microtubule-associated | -0.0180227 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0178969 |
| CLTC | clathrin, heavy chain (Hc) | -0.0174114 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0171856 |
| RPS10 | ribosomal protein S10 | -0.0164846 |
| DIAPH3 | diaphanous-related formin 3 | -0.0164549 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0162545 |
| NUP58 | nucleoporin 58 | -0.0161246 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0161029 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0160939 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.016033 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0156924 |
| SNX14 | sorting nexin 14 | -0.0156315 |
| PYGL | phosphorylase, glycogen, liver | -0.0156048 |
| RHEB | Ras homolog enriched in brain | -0.0155736 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0153627 |
| MYO9A | myosin IXA | -0.0148772 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0147976 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0147937 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0147882 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0147864 |
| CDYL | chromodomain protein, Y-like | -0.0147172 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0147117 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.014658 |
| CEP95 | centrosomal protein 95kDa | -0.0145648 |
| DNER | delta/notch-like EGF repeat containing | -0.0143967 |
| SRBD1 | S1 RNA binding domain 1 | -0.014373 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0142767 |
| RPL28 | ribosomal protein L28 | -0.0142686 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0142364 |
| CABIN1 | calcineurin binding protein 1 | -0.0140652 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0140219 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0140205 |
| KHSRP | KH-type splicing regulatory protein | -0.0137947 |
| CLIC1 | chloride intracellular channel 1 | -0.0137363 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -0.0136577 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0136423 |
| TBC1D2B | TBC1 domain family, member 2B | -0.0136213 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0135726 |
| TUBB4B | tubulin, beta 4B class IVb | -0.013564 |
| SFSWAP | splicing factor, suppressor of white-apricot family | -0.0135341 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0134615 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0134337 |
| HELZ | helicase with zinc finger | -0.0133816 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0133708 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.013363 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.013336 |
| SIN3A | SIN3 transcription regulator family member A | -0.0132983 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0132052 |
| PTMS | parathymosin | -0.0131775 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0131717 |
| RBM39 | RNA binding motif protein 39 | -0.0131558 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0131214 |
| ATG13 | autophagy related 13 | -0.0130535 |
| IMMT | inner membrane protein, mitochondrial | -0.0130515 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -0.0129583 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0129053 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0128808 |
| LAMA4 | laminin, alpha 4 | -0.0128189 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.012809 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -0.0127691 |
| TTK | TTK protein kinase | -0.0126936 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0126264 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0125714 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0125605 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0125344 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0125021 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0124825 |
| TUT4 | terminal uridylyl transferase 4 | -0.0124638 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0123843 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0123118 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0122786 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0122366 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0122344 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.0122309 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0122193 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0122078 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0121662 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0121593 |
| SET | SET nuclear proto-oncogene | -0.0120383 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0120066 |
| SEC24D | SEC24 family member D | -0.0119629 |
| RAB10 | RAB10, member RAS oncogene family | -0.0119331 |
