| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.166354 |
| FN1 | fibronectin 1 | 0.108444 |
| HMGA2 | high mobility group AT-hook 2 | 0.0976459 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0793554 |
| ASPH | aspartate beta-hydroxylase | 0.0769097 |
| STC2 | stanniocalcin 2 | 0.0746684 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0611123 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0594102 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0573072 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0570894 |
| RAI14 | retinoic acid induced 14 | 0.0537739 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0464265 |
| EFNA5 | ephrin-A5 | 0.0446419 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0436877 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0433818 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0422341 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0410498 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0396269 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0394127 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0385392 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0370598 |
| DSTN | destrin (actin depolymerizing factor) | 0.0360297 |
| GLIS3 | GLIS family zinc finger 3 | 0.0355571 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0355113 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0351406 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0345723 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0336558 |
| AEBP2 | AE binding protein 2 | 0.0326444 |
| TMSB4X | thymosin beta 4, X-linked | 0.032583 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0322756 |
| PLIN2 | perilipin 2 | 0.0321559 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0315809 |
| RASAL2 | RAS protein activator like 2 | 0.0304262 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0302551 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0297058 |
| GPC6 | glypican 6 | 0.0295997 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.02934 |
| PALLD | palladin, cytoskeletal associated protein | 0.0288263 |
| MYOF | myoferlin | 0.0285919 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0283303 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0280503 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0280118 |
| LMNA | lamin A/C | 0.0274247 |
| CADM1 | cell adhesion molecule 1 | 0.0274065 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0272845 |
| NDRG1 | N-myc downstream regulated 1 | 0.0271649 |
| S100A10 | S100 calcium binding protein A10 | 0.027073 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0270076 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0260223 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0259991 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0258225 |
| LOXL2 | lysyl oxidase-like 2 | 0.0255524 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0253999 |
| FTL | ferritin, light polypeptide | 0.025364 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0248677 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0245664 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0245595 |
| ITGA1 | integrin, alpha 1 | 0.0242981 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0242707 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0236366 |
| GPATCH2L | G patch domain containing 2-like | 0.0229313 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0227398 |
| VCL | vinculin | 0.0227398 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0225298 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0223758 |
| TMEM156 | transmembrane protein 156 | 0.0222435 |
| INTS6 | integrator complex subunit 6 | 0.0222367 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0221718 |
| DUSP6 | dual specificity phosphatase 6 | 0.0220726 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0219689 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0219261 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0218993 |
| B2M | beta-2-microglobulin | 0.0211284 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0207047 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0205287 |
| SYT1 | synaptotagmin I | 0.0205062 |
| OXR1 | oxidation resistance 1 | 0.0198691 |
| ACTG1 | actin gamma 1 | 0.0197173 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0195844 |
| RND3 | Rho family GTPase 3 | 0.0194798 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0194494 |
| NTN4 | netrin 4 | 0.0193894 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0193156 |
| NXN | nucleoredoxin | 0.0190494 |
| SFTPA2 | surfactant protein A2 | 0.0190077 |
| PRKCA | protein kinase C, alpha | 0.0186269 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0181998 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0177477 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0175995 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0173996 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0170206 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0168402 |
| SLC38A2 | solute carrier family 38, member 2 | 0.016786 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0167074 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0167051 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0164884 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.01623 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0160194 |
| FAT1 | FAT atypical cadherin 1 | 0.0157203 |
| SFRP1 | secreted frizzled-related protein 1 | 0.015698 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0636257 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0602769 |
| MT2A | metallothionein 2A | -0.0598615 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0598135 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0593079 |
| CENPF | centromere protein F, 350/400kDa | -0.0494945 |
| RPS27A | ribosomal protein S27a | -0.0428997 |
| PTMA | prothymosin, alpha | -0.037285 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0329685 |
| OGA | O-GlcNAcase | -0.0324958 |
| RPL37A | ribosomal protein L37a | -0.0309704 |
| TMSB10 | thymosin beta 10 | -0.0293817 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0290903 |
| RPL23 | ribosomal protein L23 | -0.0289474 |
| RPS12 | ribosomal protein S12 | -0.0286788 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0284734 |
| MKI67 | marker of proliferation Ki-67 | -0.0279587 |
| RPL26 | ribosomal protein L26 | -0.0279268 |
| VIM | vimentin | -0.0269557 |
| PCBP2 | poly(rC) binding protein 2 | -0.026826 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0266398 |
| AHR | aryl hydrocarbon receptor | -0.0263935 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0260542 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0243157 |
| CD44 | CD44 molecule (Indian blood group) | -0.023593 |
| TXNRD1 | thioredoxin reductase 1 | -0.0234591 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0234132 |
| NEK7 | NIMA-related kinase 7 | -0.0232487 |
| PELO | pelota homolog (Drosophila) | -0.023206 |
| SMOX | spermine oxidase | -0.0221646 |
| RPS29 | ribosomal protein S29 | -0.0221313 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0221179 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0218934 |
| UBC | ubiquitin C | -0.0216151 |
| ZNF292 | zinc finger protein 292 | -0.021195 |
| ANLN | anillin, actin binding protein | -0.0207994 |
| CANX | calnexin | -0.0207944 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0207744 |
| TFG | TRK-fused gene | -0.0207031 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.018891 |
| RNF145 | ring finger protein 145 | -0.0187325 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0177865 |
| SPAG9 | sperm associated antigen 9 | -0.0177582 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0174013 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0171609 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0171101 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0170623 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0165881 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0163199 |
| ETNK1 | ethanolamine kinase 1 | -0.0163066 |
| RHEB | Ras homolog enriched in brain | -0.0161823 |
| WDR45B | WD repeat domain 45B | -0.0158447 |
| RPS21 | ribosomal protein S21 | -0.0156635 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0156384 |
| HMGB3 | high mobility group box 3 | -0.01549 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0154802 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0154163 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0153542 |
| RPS8 | ribosomal protein S8 | -0.0152856 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0152786 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0152642 |
| NUP58 | nucleoporin 58 | -0.0152248 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0151832 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0151265 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0151044 |
| RBM39 | RNA binding motif protein 39 | -0.0148602 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0147579 |
| SUCO | SUN domain containing ossification factor | -0.0147288 |
| RPLP2 | ribosomal protein, large, P2 | -0.0146425 |
| ETV6 | ets variant 6 | -0.0146244 |
| RPL36 | ribosomal protein L36 | -0.0145744 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0144207 |
| HDLBP | high density lipoprotein binding protein | -0.014329 |
| ECT2 | epithelial cell transforming 2 | -0.0142625 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0142093 |
| RPS24 | ribosomal protein S24 | -0.0141934 |
| DIAPH3 | diaphanous-related formin 3 | -0.0139686 |
| RPS19 | ribosomal protein S19 | -0.0139659 |
| VMP1 | vacuole membrane protein 1 | -0.0138353 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0137248 |
| POU2F1 | POU class 2 homeobox 1 | -0.0136268 |
| RPS6 | ribosomal protein S6 | -0.0134753 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0133362 |
| TPX2 | TPX2, microtubule-associated | -0.0133275 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0133091 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0132946 |
| CENPE | centromere protein E, 312kDa | -0.0132126 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0132012 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0131969 |
| COG5 | component of oligomeric golgi complex 5 | -0.0131654 |
| RPS3 | ribosomal protein S3 | -0.0130966 |
| SEPTIN7 | septin 7 | -0.0130514 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0129654 |
| RPS23 | ribosomal protein S23 | -0.0127208 |
| WDR26 | WD repeat domain 26 | -0.0126142 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | -0.0123769 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0122874 |
| RPS25 | ribosomal protein S25 | -0.0121658 |
| RRM2 | ribonucleotide reductase M2 | -0.0120833 |
| RBM25 | RNA binding motif protein 25 | -0.0120735 |
