| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the LY-2584702 (tosylate salt)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.22141 |
| RPS6 | ribosomal protein S6 | 0.0925691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0867845 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0788398 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0787911 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0752828 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0651775 |
| EHBP1 | EH domain binding protein 1 | 0.0592583 |
| RPS13 | ribosomal protein S13 | 0.0581029 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0543417 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0538323 |
| RPL32 | ribosomal protein L32 | 0.0459704 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0452827 |
| RPL7A | ribosomal protein L7a | 0.0452323 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0447148 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0429243 |
| RPS3 | ribosomal protein S3 | 0.0419256 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0415949 |
| RPS25 | ribosomal protein S25 | 0.0412415 |
| RPL37A | ribosomal protein L37a | 0.0394102 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0386069 |
| RPL31 | ribosomal protein L31 | 0.0382335 |
| RPL11 | ribosomal protein L11 | 0.0381212 |
| RPS19 | ribosomal protein S19 | 0.0380155 |
| RPL35A | ribosomal protein L35a | 0.037999 |
| RPL12 | ribosomal protein L12 | 0.0374654 |
| RPLP0 | ribosomal protein, large, P0 | 0.0370758 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0358603 |
| NEBL | nebulette | 0.0353082 |
| VCL | vinculin | 0.0351631 |
| RPS8 | ribosomal protein S8 | 0.0348988 |
| RPL19 | ribosomal protein L19 | 0.0333561 |
| LDHA | lactate dehydrogenase A | 0.0333209 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0322313 |
| PGK1 | phosphoglycerate kinase 1 | 0.0320546 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.031361 |
| RPS5 | ribosomal protein S5 | 0.0313222 |
| CADPS | Ca++-dependent secretion activator | 0.0309147 |
| EPCAM | epithelial cell adhesion molecule | 0.0306707 |
| RPS21 | ribosomal protein S21 | 0.0302325 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0298282 |
| RPL28 | ribosomal protein L28 | 0.0296975 |
| RPL37 | ribosomal protein L37 | 0.0292641 |
| RPS23 | ribosomal protein S23 | 0.0290457 |
| WWC1 | WW and C2 domain containing 1 | 0.0290309 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0289207 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0287124 |
| FRMD5 | FERM domain containing 5 | 0.0281652 |
| RPLP2 | ribosomal protein, large, P2 | 0.028053 |
| B2M | beta-2-microglobulin | 0.0276705 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0273248 |
| RPL13A | ribosomal protein L13a | 0.0271526 |
| RPL10A | ribosomal protein L10a | 0.0270814 |
| RPL36 | ribosomal protein L36 | 0.0269283 |
| EGR1 | early growth response 1 | 0.0269054 |
| RPL15 | ribosomal protein L15 | 0.026902 |
| MYO1E | myosin IE | 0.0266305 |
| RPL9 | ribosomal protein L9 | 0.0263745 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0262557 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0261172 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0260195 |
| RPL8 | ribosomal protein L8 | 0.0255206 |
| RACK1 | receptor for activated C kinase 1 | 0.0254258 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0250542 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0250314 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0250122 |
| RPL18 | ribosomal protein L18 | 0.02463 |
| RPS17 | ribosomal protein S17 | 0.024628 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0244161 |
| MTDH | metadherin | 0.02412 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0240233 |
| BCL2L1 | BCL2-like 1 | 0.0239897 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0239679 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0239273 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0237735 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0235311 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0233931 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0231752 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0231555 |
| SMAD2 | SMAD family member 2 | 0.0231457 |
| HMGA1 | high mobility group AT-hook 1 | 0.0231334 |
| INTS6 | integrator complex subunit 6 | 0.0230934 |
| ASTN2 | astrotactin 2 | 0.023072 |
| THOC2 | THO complex 2 | 0.0230406 |
| RPLP1 | ribosomal protein, large, P1 | 0.0230189 |
| NRP1 | neuropilin 1 | 0.0229331 |
| RPS12 | ribosomal protein S12 | 0.0227037 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0223089 |
| RPS14 | ribosomal protein S14 | 0.0221734 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0220689 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0220646 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.022035 |
| CUX1 | cut-like homeobox 1 | 0.0219207 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.021687 |
| RUNX1 | runt-related transcription factor 1 | 0.0216519 |
| RPS29 | ribosomal protein S29 | 0.0214547 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0213869 |
| ZNRF3 | zinc and ring finger 3 | 0.0213801 |
| SON | SON DNA binding protein | 0.0212885 |
| RPL27A | ribosomal protein L27a | 0.0211213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.114569 |
| PTMA | prothymosin, alpha | -0.105809 |
| AHNAK | AHNAK nucleoprotein | -0.0787542 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0755869 |
| KRT8 | keratin 8, type II | -0.0673351 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0651742 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0608588 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0557994 |
| EZR | ezrin | -0.053838 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0522824 |
| TMSB10 | thymosin beta 10 | -0.0479775 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0478877 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0466775 |
| OGA | O-GlcNAcase | -0.0463513 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0462118 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0460735 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0453831 |
| PCBP2 | poly(rC) binding protein 2 | -0.0450553 |
| CANX | calnexin | -0.0432733 |
| RBM39 | RNA binding motif protein 39 | -0.0422213 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0410215 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0400436 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0389767 |
| RPS27A | ribosomal protein S27a | -0.0387581 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0372077 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0368371 |
| XPO1 | exportin 1 | -0.0365348 |
| NCKAP1 | NCK-associated protein 1 | -0.0364267 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0358364 |
| HMGB2 | high mobility group box 2 | -0.0355219 |
| MATR3 | matrin 3 | -0.033433 |
| SQSTM1 | sequestosome 1 | -0.0330798 |
| TPX2 | TPX2, microtubule-associated | -0.0325311 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.032379 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0321982 |
| JUN | jun proto-oncogene | -0.0321771 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0319084 |
| TPM3 | tropomyosin 3 | -0.0317178 |
| ZNF292 | zinc finger protein 292 | -0.0313679 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0309302 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0307492 |
| RYBP | RING1 and YY1 binding protein | -0.0292341 |
| ACTN4 | actinin, alpha 4 | -0.0290774 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0288184 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0283855 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.028371 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0278717 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0272278 |
| PLEC | plectin | -0.027108 |
| RHEB | Ras homolog enriched in brain | -0.0271005 |
| RBM33 | RNA binding motif protein 33 | -0.0269723 |
| TFG | TRK-fused gene | -0.0268723 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0266456 |
| RTN4 | reticulon 4 | -0.0265754 |
| APP | amyloid beta (A4) precursor protein | -0.0263567 |
| FMR1 | fragile X mental retardation 1 | -0.0262234 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0257353 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0248639 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0248626 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0247681 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0242164 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0241648 |
| H1-0 | H1.0 linker histone | -0.0233375 |
| SEPTIN7 | septin 7 | -0.0231512 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0231511 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0230794 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0228911 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0228749 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0227481 |
| S100A6 | S100 calcium binding protein A6 | -0.0227242 |
| USP3 | ubiquitin specific peptidase 3 | -0.0223444 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0221492 |
| SPAG9 | sperm associated antigen 9 | -0.0221134 |
| NPTN | neuroplastin | -0.0220602 |
| SDC4 | syndecan 4 | -0.0219504 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0217988 |
| PDS5B | PDS5 cohesin associated factor B | -0.021524 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0214295 |
| ANXA2 | annexin A2 | -0.0213148 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0209671 |
| RBM25 | RNA binding motif protein 25 | -0.0205549 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0204002 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0202209 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0201513 |
| FUS | FUS RNA binding protein | -0.0192417 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0191814 |
| ABHD12 | abhydrolase domain containing 12 | -0.0191558 |
| PERP | PERP, TP53 apoptosis effector | -0.0191005 |
| NEK7 | NIMA-related kinase 7 | -0.0189565 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0187823 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0186854 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0185966 |
| TXNRD1 | thioredoxin reductase 1 | -0.0184501 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0181685 |
| AFDN | afadin, adherens junction formation factor | -0.0181003 |
| ORC4 | origin recognition complex, subunit 4 | -0.0180524 |
| MYO6 | myosin VI | -0.0180358 |
| SRPK2 | SRSF protein kinase 2 | -0.0179611 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0179026 |
| SERINC3 | serine incorporator 3 | -0.0177517 |
