| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY-2584702 (tosylate salt) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY-2584702 (tosylate salt)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.131534 |
| ACTG1 | actin gamma 1 | 0.125481 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.117132 |
| EGFR | epidermal growth factor receptor | 0.109593 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0920917 |
| LAMC2 | laminin, gamma 2 | 0.0918698 |
| ATXN1 | ataxin 1 | 0.0835268 |
| RCOR1 | REST corepressor 1 | 0.0783225 |
| LAMA4 | laminin, alpha 4 | 0.069403 |
| EGR1 | early growth response 1 | 0.0693843 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0692452 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0633451 |
| SEPTIN9 | septin 9 | 0.0605496 |
| EMP1 | epithelial membrane protein 1 | 0.0583689 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0568486 |
| SGMS2 | sphingomyelin synthase 2 | 0.055798 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0548221 |
| SMAD3 | SMAD family member 3 | 0.0509162 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0506872 |
| SNX9 | sorting nexin 9 | 0.0497501 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.047722 |
| FHIT | fragile histidine triad | 0.047713 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0463606 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0456036 |
| FAT1 | FAT atypical cadherin 1 | 0.0454819 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0450118 |
| LAMB3 | laminin, beta 3 | 0.0443847 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0439441 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0437521 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0430888 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0429298 |
| LDHA | lactate dehydrogenase A | 0.0426684 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0420549 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0418878 |
| RAD51B | RAD51 paralog B | 0.0415036 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0405774 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0399037 |
| LMO7 | LIM domain 7 | 0.0398772 |
| ABR | active BCR-related | 0.0398251 |
| FLOT1 | flotillin 1 | 0.0396618 |
| NUP50 | nucleoporin 50kDa | 0.0391008 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0390333 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0389972 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0386032 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0381209 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0380657 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0369876 |
| YAP1 | Yes-associated protein 1 | 0.0367944 |
| EFNB2 | ephrin-B2 | 0.0367157 |
| EZR | ezrin | 0.0361847 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0359936 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0359068 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0346228 |
| DSPP | dentin sialophosphoprotein | 0.0344436 |
| ACTN4 | actinin, alpha 4 | 0.0341691 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0340432 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0332894 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0329096 |
| DST | dystonin | 0.0327415 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.032312 |
| ANXA2 | annexin A2 | 0.0314764 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0312949 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0312898 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0310161 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0308637 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0307897 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0305623 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0293314 |
| CD9 | CD9 molecule | 0.0287604 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0286408 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0278768 |
| BRD2 | bromodomain containing 2 | 0.0276816 |
| RPL3 | ribosomal protein L3 | 0.0274344 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0268022 |
| ITGA6 | integrin, alpha 6 | 0.026775 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0266335 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0265006 |
| CMIP | c-Maf inducing protein | 0.0257582 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0255854 |
| POTEF | POTE ankyrin domain family, member F | 0.0252238 |
| RPL7 | ribosomal protein L7 | 0.0249917 |
| RACK1 | receptor for activated C kinase 1 | 0.0249034 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0248898 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.0243109 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0242315 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0239974 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0238079 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0236644 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0236349 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.023489 |
| SCFD1 | sec1 family domain containing 1 | 0.0234642 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0230931 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0230346 |
| CTSB | cathepsin B | 0.022705 |
| S100A6 | S100 calcium binding protein A6 | 0.022673 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.022453 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0223196 |
| JMJD1C | jumonji domain containing 1C | 0.0218739 |
| SPATA13 | spermatogenesis associated 13 | 0.0217813 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.021767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.205381 |
| PTMA | prothymosin, alpha | -0.192147 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0829229 |
| TMSB10 | thymosin beta 10 | -0.0821548 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0665237 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0557262 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0472878 |
| OXR1 | oxidation resistance 1 | -0.0460329 |
| USP3 | ubiquitin specific peptidase 3 | -0.0395403 |
| GDF15 | growth differentiation factor 15 | -0.0382896 |
| RPS24 | ribosomal protein S24 | -0.0371254 |
| GOLGA4 | golgin A4 | -0.0349781 |
| MT1X | metallothionein 1X | -0.0349173 |
| RPL35A | ribosomal protein L35a | -0.0325454 |
| RNF145 | ring finger protein 145 | -0.0320295 |
| RPS19 | ribosomal protein S19 | -0.0314625 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0310085 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0309358 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305599 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0304868 |
| RUNX2 | runt-related transcription factor 2 | -0.0301388 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.029612 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0292436 |
| HDAC2 | histone deacetylase 2 | -0.0291966 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0286439 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0285116 |
| SERINC5 | serine incorporator 5 | -0.0275969 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0275504 |
| NEK7 | NIMA-related kinase 7 | -0.0273766 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.026478 |
| RPLP2 | ribosomal protein, large, P2 | -0.0264124 |
| RBM25 | RNA binding motif protein 25 | -0.0263371 |
| MT2A | metallothionein 2A | -0.0256073 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.0253518 |
| RLF | rearranged L-myc fusion | -0.0252276 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0249817 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0248553 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0247759 |
| ZNF292 | zinc finger protein 292 | -0.0244959 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.024199 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0240553 |
| TOP1 | topoisomerase (DNA) I | -0.0238124 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0237095 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0235875 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.023406 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0234032 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.023352 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0232216 |
| RNF43 | ring finger protein 43 | -0.0223297 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0223139 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0222723 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0219323 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0217564 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.020855 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0200394 |
| WDR45B | WD repeat domain 45B | -0.0199432 |
| TNPO1 | transportin 1 | -0.0199409 |
| OGA | O-GlcNAcase | -0.0198098 |
| TXNRD1 | thioredoxin reductase 1 | -0.0196611 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0189847 |
| YBX1 | Y box binding protein 1 | -0.0189436 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0187401 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0185636 |
| HDAC3 | histone deacetylase 3 | -0.0184121 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0179019 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0178817 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0177784 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0175291 |
| RPL34 | ribosomal protein L34 | -0.0174702 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0174553 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0172644 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0172503 |
| MAP4 | microtubule-associated protein 4 | -0.0172334 |
| NUP58 | nucleoporin 58 | -0.0171933 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0171917 |
| INSIG2 | insulin induced gene 2 | -0.0170815 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0170523 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0170477 |
| SEPTIN7 | septin 7 | -0.0170237 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0170208 |
| HMGB1 | high mobility group box 1 | -0.0169803 |
| RBM39 | RNA binding motif protein 39 | -0.016927 |
| PARD3 | par-3 family cell polarity regulator | -0.0167645 |
| RAB6A | RAB6A, member RAS oncogene family | -0.016582 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0164649 |
| SEC24B | SEC24 family member B | -0.016378 |
| RFX7 | regulatory factor X, 7 | -0.0163779 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0162722 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | -0.0162418 |
| CDC73 | cell division cycle 73 | -0.0160751 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0158393 |
| OLA1 | Obg-like ATPase 1 | -0.0157201 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0156767 |
| TFG | TRK-fused gene | -0.0156425 |
| TPR | translocated promoter region, nuclear basket protein | -0.0154606 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.015409 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0153637 |
| NFIA | nuclear factor I/A | -0.0153589 |
| AK2 | adenylate kinase 2 | -0.0153106 |
| TFRC | transferrin receptor | -0.0151079 |
