| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the LY-294002-258 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| AXIN1 | axin 1 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CADM3 | cell adhesion molecule 3 |
| CAPN9 | calpain 9 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CHKB | choline kinase beta |
| CLIP3 | CAP-GLY domain containing linker protein 3 |
| CPE | carboxypeptidase E |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FAM184A | family with sequence similarity 184, member A |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALR3 | galanin receptor 3 |
| GLG1 | golgi glycoprotein 1 |
| GLRX3 | glutaredoxin 3 |
| GM2A | GM2 ganglioside activator |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GOLPH3L | golgi phosphoprotein 3-like |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HBP1 | HMG-box transcription factor 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HNMT | histamine N-methyltransferase |
| HOXA10 | homeobox A10 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGB5 | integrin, beta 5 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KLHL35 | kelch-like family member 35 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCOLN3 | mucolipin 3 |
| MMP19 | matrix metallopeptidase 19 |
| MST1 | macrophage stimulating 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NDRG2 | NDRG family member 2 |
| NF1 | neurofibromin 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRP1 | neuropilin 1 |
| NUP160 | nucleoporin 160kDa |
| NUPL2 | nucleoporin like 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PAX4 | paired box 4 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PRKCA | protein kinase C, alpha |
| RANBP10 | RAN binding protein 10 |
| RNF141 | ring finger protein 141 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS11 | ribosomal protein S11 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SIDT2 | SID1 transmembrane family, member 2 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STX12 | syntaxin 12 |
| TES | testin LIM domain protein |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TRIM10 | tripartite motif containing 10 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TXN | thioredoxin |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| WDR48 | WD repeat domain 48 |
| WDR59 | WD repeat domain 59 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ADORA2B | adenosine A2b receptor |
| AEN | apoptosis enhancing nuclease |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMPH | amphiphysin |
| APOB | apolipoprotein B |
| AQP8 | aquaporin 8 |
| BARX2 | BARX homeobox 2 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CAV3 | caveolin 3 |
| CD207 | CD207 molecule, langerin |
| CD70 | CD70 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHD2 | chromodomain helicase DNA binding protein 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CORO2A | coronin, actin binding protein, 2A |
| CORT | cortistatin |
| CUEDC1 | CUE domain containing 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGKZ | diacylglycerol kinase, zeta |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DRP2 | dystrophin related protein 2 |
| DYSF | dysferlin |
| ECE2 | endothelin converting enzyme 2 |
| FASTKD1 | FAST kinase domains 1 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGF6 | fibroblast growth factor 6 |
| FRMD1 | FERM domain containing 1 |
| FXYD1 | FXYD domain containing ion transport regulator 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJB1 | gap junction protein, beta 1, 32kDa |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GYPC | glycophorin C (Gerbich blood group) |
| HCK | HCK proto-oncogene, Src family tyrosine kinase |
| HCRT | hypocretin (orexin) neuropeptide precursor |
| HOMER1 | homer scaffolding protein 1 |
| HOXB1 | homeobox B1 |
| HOXB2 | homeobox B2 |
| HUNK | hormonally up-regulated Neu-associated kinase |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF8 | interferon regulatory factor 8 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNC4 | potassium channel, voltage gated Shaw related subfamily C, member 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRT75 | keratin 75, type II |
| LIN28A | lin-28 homolog A (C. elegans) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MALL | mal, T-cell differentiation protein-like |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MVD | mevalonate (diphospho) decarboxylase |
| NMRK2 | nicotinamide riboside kinase 2 |
| NPPA | natriuretic peptide A |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| NXF2 | nuclear RNA export factor 2 |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PNOC | prepronociceptin |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PRDM14 | PR domain containing 14 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) |
| RAB4B | RAB4B, member RAS oncogene family |
| RAP1A | RAP1A, member of RAS oncogene family |
| RASIP1 | Ras interacting protein 1 |
| REC8 | REC8 meiotic recombination protein |
| RORC | RAR-related orphan receptor C |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCARA3 | scavenger receptor class A, member 3 |
| SMYD5 | SMYD family member 5 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SP140L | SP140 nuclear body protein-like |
| SPEF1 | sperm flagellar 1 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| STX2 | syntaxin 2 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCAP | titin-cap |
| TG | thyroglobulin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USP18 | ubiquitin specific peptidase 18 |
