| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the LY-294002-318 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATG13 | autophagy related 13 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAMKV | CaM kinase-like vesicle-associated |
| CCNG2 | cyclin G2 |
| CCNK | cyclin K |
| CD5 | CD5 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CEP63 | centrosomal protein 63kDa |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLDN15 | claudin 15 |
| CPT2 | carnitine palmitoyltransferase 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DST | dystonin |
| DUS2 | dihydrouridine synthase 2 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EFCAB1 | EF-hand calcium binding domain 1 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EIF5B | eukaryotic translation initiation factor 5B |
| FBXO38 | F-box protein 38 |
| FERMT1 | fermitin family member 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLG1 | golgi glycoprotein 1 |
| GPR4 | G protein-coupled receptor 4 |
| GSTT1 | glutathione S-transferase theta 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HBP1 | HMG-box transcription factor 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H3I | histone cluster 1, H3i |
| HIST1H4J | histone cluster 1, H4j |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| ING4 | inhibitor of growth family, member 4 |
| IRS2 | insulin receptor substrate 2 |
| KLHL24 | kelch-like family member 24 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAGEB2 | melanoma antigen family B2 |
| MAOA | monoamine oxidase A |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MCOLN1 | mucolipin 1 |
| MFAP3 | microfibrillar-associated protein 3 |
| MGC2889 | uncharacterized protein MGC2889 |
| MLXIP | MLX interacting protein |
| MXD3 | MAX dimerization protein 3 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NRP1 | neuropilin 1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PAX1 | paired box 1 |
| PAX2 | paired box 2 |
| PAX8 | paired box 8 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLK3 | polo-like kinase 3 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPL14 | ribosomal protein L14 |
| RRAGD | Ras-related GTP binding D |
| RTN2 | reticulon 2 |
| RXRB | retinoid X receptor, beta |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMAD3 | SMAD family member 3 |
| SMO | smoothened, frizzled class receptor |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SQSTM1 | sequestosome 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TCP10 | t-complex 10 |
| TMEM161A | transmembrane protein 161A |
| TMEM176A | transmembrane protein 176A |
| TMSB4Y | thymosin beta 4, Y-linked |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TOM1L2 | target of myb1-like 2 (chicken) |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| AIM2 | absent in melanoma 2 |
| ALX3 | ALX homeobox 3 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC7 | armadillo repeat containing 7 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BNC1 | basonuclin 1 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC82 | coiled-coil domain containing 82 |
| CD38 | CD38 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHAT | choline O-acetyltransferase |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLEC4E | C-type lectin domain family 4, member E |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CRY1 | cryptochrome circadian clock 1 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DEFB1 | defensin, beta 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DYSF | dysferlin |
| EXOSC9 | exosome component 9 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GRM2 | glutamate receptor, metabotropic 2 |
| H2AFY2 | H2A histone family, member Y2 |
| HDC | histidine decarboxylase |
| HEATR3 | HEAT repeat containing 3 |
| IFT140 | intraflagellar transport 140 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIFAP3 | kinesin-associated protein 3 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| LENEP | lens epithelial protein |
| LHX1 | LIM homeobox 1 |
| LHX6 | LIM homeobox 6 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| METTL16 | methyltransferase like 16 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MTMR10 | myotubularin related protein 10 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYO1F | myosin IF |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NPY4R | neuropeptide Y receptor Y4 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PGBD5 | piggyBac transposable element derived 5 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PICK1 | protein interacting with PRKCA 1 |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) |
| PXDC1 | PX domain containing 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RXRG | retinoid X receptor, gamma |
| S100A2 | S100 calcium binding protein A2 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNPO | synaptopodin |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM140 | transmembrane protein 140 |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| UMOD | uromodulin |
| USP18 | ubiquitin specific peptidase 18 |
| WDR46 | WD repeat domain 46 |
| XAF1 | XIAP associated factor 1 |
| ZFP36 | ZFP36 ring finger protein |
