| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the LY-294002-401 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ACVR1B | activin A receptor, type IB |
| ADH6 | alcohol dehydrogenase 6 (class V) |
| ADRA2B | adrenoceptor alpha 2B |
| AMPH | amphiphysin |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BMP8B | bone morphogenetic protein 8b |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C8B | complement component 8, beta polypeptide |
| CA6 | carbonic anhydrase VI |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CCPG1 | cell cycle progression 1 |
| CD5 | CD5 molecule |
| CD6 | CD6 molecule |
| CD82 | CD82 molecule |
| CD86 | CD86 molecule |
| CD8B | CD8b molecule |
| CHD2 | chromodomain helicase DNA binding protein 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRYAB | crystallin, alpha B |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DUS2 | dihydrouridine synthase 2 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EGR1 | early growth response 1 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| ELK1 | ELK1, member of ETS oncogene family |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ESR2 | estrogen receptor 2 (ER beta) |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FBXO41 | F-box protein 41 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGL1 | fibrinogen-like 1 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| FOLR2 | folate receptor 2 (fetal) |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HAP1 | huntingtin-associated protein 1 |
| HMX1 | H6 family homeobox 1 |
| HOXB1 | homeobox B1 |
| IFNA4 | interferon, alpha 4 |
| IL2RG | interleukin 2 receptor, gamma |
| INA | internexin neuronal intermediate filament protein, alpha |
| KIFAP3 | kinesin-associated protein 3 |
| KLHL24 | kelch-like family member 24 |
| KLHL28 | kelch-like family member 28 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC01558 | long intergenic non-protein coding RNA 1558 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC23 | leucine rich repeat containing 23 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAGEA5 | melanoma antigen family A5 |
| MAGEB2 | melanoma antigen family B2 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MST1 | macrophage stimulating 1 |
| MYO15B | myosin XVB |
| MYOG | myogenin (myogenic factor 4) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLIN2 | perilipin 2 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PROP1 | PROP paired-like homeobox 1 |
| PRSS3 | protease, serine, 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB11B | RAB11B, member RAS oncogene family |
| RGSL1 | regulator of G-protein signaling like 1 |
| RNMT | RNA (guanine-7-) methyltransferase |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERHL2 | serine hydrolase-like 2 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPON1 | spondin 1, extracellular matrix protein |
| SSTR2 | somatostatin receptor 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TCP11 | t-complex 11, testis-specific |
| TLL2 | tolloid-like 2 |
| TRAC | T cell receptor alpha constant |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TYMP | thymidine phosphorylase |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZNF460 | zinc finger protein 460 |
| Symbol | Name |
|---|---|
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADORA2B | adenosine A2b receptor |
| ADRA2C | adrenoceptor alpha 2C |
| ANKRD40 | ankyrin repeat domain 40 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATXN2 | ataxin 2 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C4BPA | complement component 4 binding protein, alpha |
| CDC45 | cell division cycle 45 |
| CDK3 | cyclin-dependent kinase 3 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN17 | claudin 17 |
| CORT | cortistatin |
| CRY1 | cryptochrome circadian clock 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAGLA | diacylglycerol lipase, alpha |
| DCLRE1A | DNA cross-link repair 1A |
| DDA1 | DET1 and DDB1 associated 1 |
| DOK3 | docking protein 3 |
| EHD3 | EH-domain containing 3 |
| ENDOG | endonuclease G |
| EXOSC10 | exosome component 10 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM188A | family with sequence similarity 188, member A |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXD1 | forkhead box D1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GDF3 | growth differentiation factor 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMIP | GEM interacting protein |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GPR19 | G protein-coupled receptor 19 |
| HMHA1 | histocompatibility (minor) HA-1 |
| IFT81 | intraflagellar transport 81 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IL25 | interleukin 25 |
| IL4R | interleukin 4 receptor |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KIF20B | kinesin family member 20B |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGMN | legumain |
| LMTK1 | lemur tail kinase 1 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MDK | midkine (neurite growth-promoting factor 2) |
| MTRF1 | mitochondrial translational release factor 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NCS1 | neuronal calcium sensor 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OLFML2A | olfactomedin-like 2A |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCDHB12 | protocadherin beta 12 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PGBD5 | piggyBac transposable element derived 5 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PTK6 | protein tyrosine kinase 6 |
| RAB23 | RAB23, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAI14 | retinoic acid induced 14 |
| RNF121 | ring finger protein 121 |
| RORC | RAR-related orphan receptor C |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMYD5 | SMYD family member 5 |
| SNCB | synuclein, beta |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| T | T, brachyury homolog (mouse) |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM127 | transmembrane protein 127 |
| TMEM53 | transmembrane protein 53 |
| TRAF2 | TNF receptor-associated factor 2 |
| TTR | transthyretin |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| WDR13 | WD repeat domain 13 |
| WDR18 | WD repeat domain 18 |
| WDR46 | WD repeat domain 46 |
| WDR91 | WD repeat domain 91 |
| WT1-AS | WT1 antisense RNA |
| WWC2 | WW and C2 domain containing 2 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF701 | zinc finger protein 701 |
