| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the LY-294002-4451 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| ADRA1D | adrenoceptor alpha 1D |
| AIF1 | allograft inflammatory factor 1 |
| APOL3 | apolipoprotein L, 3 |
| ARSD | arylsulfatase D |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| BCL6 | B-cell CLL/lymphoma 6 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CCDC40 | coiled-coil domain containing 40 |
| CCDC7 | coiled-coil domain containing 7 |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CD80 | CD80 molecule |
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CEP68 | centrosomal protein 68kDa |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CORT | cortistatin |
| CT62 | cancer/testis antigen 62 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| EPS8L3 | EPS8-like 3 |
| FAM63A | family with sequence similarity 63, member A |
| FERMT2 | fermitin family member 2 |
| FGF6 | fibroblast growth factor 6 |
| FZD4 | frizzled class receptor 4 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| HBB | hemoglobin, beta |
| HBP1 | HMG-box transcription factor 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST2H2BE | histone cluster 2, H2be |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| IRS2 | insulin receptor substrate 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLHL24 | kelch-like family member 24 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRN3 | leucine rich repeat neuronal 3 |
| LSP1 | lymphocyte-specific protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRF1 | nuclear respiratory factor 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLIN2 | perilipin 2 |
| PRMT2 | protein arginine methyltransferase 2 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| REC8 | REC8 meiotic recombination protein |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STON1 | stonin 1 |
| SYCP1 | synaptonemal complex protein 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TEF | thyrotrophic embryonic factor |
| TESK2 | testis-specific kinase 2 |
| TEX15 | testis expressed 15 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM140 | transmembrane protein 140 |
| TRIM2 | tripartite motif containing 2 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS9D1 | VPS9 domain containing 1 |
| WDR78 | WD repeat domain 78 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C3 | complement component 3 |
| CCDC86 | coiled-coil domain containing 86 |
| CDC25A | cell division cycle 25A |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDC45 | cell division cycle 45 |
| CPA4 | carboxypeptidase A4 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIXDC1 | DIX domain containing 1 |
| EN1 | engrailed homeobox 1 |
| EN2 | engrailed homeobox 2 |
| EPN3 | epsin 3 |
| FAM53B | family with sequence similarity 53, member B |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GALE | UDP-galactose-4-epimerase |
| GATAD2A | GATA zinc finger domain containing 2A |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GTF2I | general transcription factor IIi |
| HAS2 | hyaluronan synthase 2 |
| HEATR3 | HEAT repeat containing 3 |
| HOXA1 | homeobox A1 |
| IFI44L | interferon-induced protein 44-like |
| IL12A | interleukin 12A |
| IL7R | interleukin 7 receptor |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LIPG | lipase, endothelial |
| MCM10 | minichromosome maintenance complex component 10 |
| METTL16 | methyltransferase like 16 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MOCOS | molybdenum cofactor sulfurase |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3A | mucin 3A, cell surface associated |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NDP | Norrie disease (pseudoglioma) |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NID2 | nidogen 2 (osteonidogen) |
| NOP2 | NOP2 nucleolar protein |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OSMR | oncostatin M receptor |
| OXTR | oxytocin receptor |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PALMD | palmdelphin |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PMM2 | phosphomannomutase 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| QSER1 | glutamine and serine rich 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RABEPK | Rab9 effector protein with kelch motifs |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMYD5 | SMYD family member 5 |
| SPHK1 | sphingosine kinase 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNPO | synaptopodin |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIPIN | TIMELESS interacting protein |
| TMEM180 | transmembrane protein 180 |
| TOR3A | torsin family 3, member A |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM16 | tripartite motif containing 16 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| UGT8 | UDP glycosyltransferase 8 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR4 | WD repeat domain 4 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| XBP1 | X-box binding protein 1 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF573 | zinc finger protein 573 |
| ZNF747 | zinc finger protein 747 |
