| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the LY-294002-4460 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACTN2 | actinin, alpha 2 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AMT | aminomethyltransferase |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| ATXN1 | ataxin 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CD53 | CD53 molecule |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| DKFZP434C153 | DKFZP434C153 protein |
| DSC2 | desmocollin 2 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| GAB1 | GRB2-associated binding protein 1 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GTPBP1 | GTP binding protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST2H2BE | histone cluster 2, H2be |
| HIST3H2A | histone cluster 3, H2a |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL33 | interleukin 33 |
| IL6ST | interleukin 6 signal transducer |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIAA1109 | KIAA1109 |
| KLHL24 | kelch-like family member 24 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MEGF9 | multiple EGF-like-domains 9 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTM1 | myotubularin 1 |
| NNMT | nicotinamide N-methyltransferase |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRF1 | nuclear respiratory factor 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLSCR4 | phospholipid scramblase 4 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTCH1 | patched 1 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| REEP2 | receptor accessory protein 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RND1 | Rho family GTPase 1 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RUNDC3A | RUN domain containing 3A |
| RUNX1 | runt-related transcription factor 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH3PXD2A | SH3 and PX domains 2A |
| SLIT1 | slit homolog 1 (Drosophila) |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STON1 | stonin 1 |
| TAPBP | TAP binding protein (tapasin) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TSGA10 | testis specific, 10 |
| TSPAN12 | tetraspanin 12 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TUBBP5 | tubulin, beta pseudogene 5 |
| VCX2 | variable charge, X-linked 2 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AEN | apoptosis enhancing nuclease |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| BMP4 | bone morphogenetic protein 4 |
| CAPN5 | calpain 5 |
| CCDC86 | coiled-coil domain containing 86 |
| CD82 | CD82 molecule |
| CDC25A | cell division cycle 25A |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COBL | cordon-bleu WH2 repeat protein |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDN | dendrin |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| FBRS | fibrosin |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FZD8 | frizzled class receptor 8 |
| GBX2 | gastrulation brain homeobox 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPR39 | G protein-coupled receptor 39 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HAS2 | hyaluronan synthase 2 |
| HOXC5 | homeobox C5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL12A | interleukin 12A |
| IL17RB | interleukin 17 receptor B |
| IL4R | interleukin 4 receptor |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRRC61 | leucine rich repeat containing 61 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| NDP | Norrie disease (pseudoglioma) |
| NOP2 | NOP2 nucleolar protein |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PALMD | palmdelphin |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLA1A | phospholipase A1 member A |
| PODXL2 | podocalyxin-like 2 |
| POLM | polymerase (DNA directed), mu |
| PPAN | peter pan homolog (Drosophila) |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR5 | proline rich 5 (renal) |
| PRR7 | proline rich 7 (synaptic) |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS1 | pseudouridylate synthase 1 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRP1 | ribosomal RNA processing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMYD5 | SMYD family member 5 |
| SPHK1 | sphingosine kinase 1 |
| SPRYD7 | SPRY domain containing 7 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| THOP1 | thimet oligopeptidase 1 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM16 | tripartite motif containing 16 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBB2B | tubulin, beta 2B class IIb |
| UBL4A | ubiquitin-like 4A |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YY2 | YY2 transcription factor |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF573 | zinc finger protein 573 |
