| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the LY-294002-4463 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABI2 | abl-interactor 2 |
| AGXT | alanine-glyoxylate aminotransferase |
| AHSP | alpha hemoglobin stabilizing protein |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOE | apolipoprotein E |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARSD | arylsulfatase D |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CCNG2 | cyclin G2 |
| CEP135 | centrosomal protein 135kDa |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CRYAB | crystallin, alpha B |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSC2 | desmocollin 2 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ETV1 | ets variant 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| GAB1 | GRB2-associated binding protein 1 |
| GFER | growth factor, augmenter of liver regeneration |
| GRB7 | growth factor receptor-bound protein 7 |
| GRM2 | glutamate receptor, metabotropic 2 |
| GSTM5 | glutathione S-transferase mu 5 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST3H2A | histone cluster 3, H2a |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IL6ST | interleukin 6 signal transducer |
| IRS2 | insulin receptor substrate 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KERA | keratocan |
| KIAA1107 | KIAA1107 |
| KLHL24 | kelch-like family member 24 |
| LAMA2 | laminin, alpha 2 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAK | male germ cell-associated kinase |
| MAP2 | microtubule-associated protein 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MED25 | mediator complex subunit 25 |
| MEGF6 | multiple EGF-like-domains 6 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PCNX | pecanex homolog (Drosophila) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLSCR4 | phospholipid scramblase 4 |
| PRKY | protein kinase, Y-linked, pseudogene |
| PRMT2 | protein arginine methyltransferase 2 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAD51 | RAD51 recombinase |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RET | ret proto-oncogene |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPS11 | ribosomal protein S11 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SF1 | splicing factor 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STON1 | stonin 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TESK2 | testis-specific kinase 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TLN2 | talin 2 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TTC12 | tetratricopeptide repeat domain 12 |
| USP53 | ubiquitin specific peptidase 53 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| Symbol | Name |
|---|---|
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BEX1 | brain expressed, X-linked 1 |
| C3 | complement component 3 |
| CAPN15 | calpain 15 |
| CCDC86 | coiled-coil domain containing 86 |
| CDH7 | cadherin 7, type 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COL9A3 | collagen, type IX, alpha 3 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| EFNA3 | ephrin-A3 |
| EPN3 | epsin 3 |
| FAM57A | family with sequence similarity 57, member A |
| FBXO31 | F-box protein 31 |
| FCHO1 | FCH domain only 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FZD8 | frizzled class receptor 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| H2AFY2 | H2A histone family, member Y2 |
| HAS2 | hyaluronan synthase 2 |
| HOXC13 | homeobox C13 |
| HSPB8 | heat shock 22kDa protein 8 |
| IFI44L | interferon-induced protein 44-like |
| IL12A | interleukin 12A |
| IL17RB | interleukin 17 receptor B |
| INO80D | INO80 complex subunit D |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KLHL3 | kelch-like family member 3 |
| LIPG | lipase, endothelial |
| LRRC61 | leucine rich repeat containing 61 |
| MDFI | MyoD family inhibitor |
| METTL1 | methyltransferase like 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDP | Norrie disease (pseudoglioma) |
| NOP2 | NOP2 nucleolar protein |
| NPR3 | natriuretic peptide receptor 3 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| OXTR | oxytocin receptor |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLM | polymerase (DNA directed), mu |
| POP7 | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPAN | peter pan homolog (Drosophila) |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PUS1 | pseudouridylate synthase 1 |
| RABEPK | Rab9 effector protein with kelch motifs |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SH2D2A | SH2 domain containing 2A |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SPHK1 | sphingosine kinase 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TEAD4 | TEA domain family member 4 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM180 | transmembrane protein 180 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA3D | tubulin, alpha 3d |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UGT8 | UDP glycosyltransferase 8 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR46 | WD repeat domain 46 |
| WDR74 | WD repeat domain 74 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF239 | zinc finger protein 239 |
| ZNF41 | zinc finger protein 41 |
| ZNF787 | zinc finger protein 787 |