| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the LY-294002-5213 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADORA1 | adenosine A1 receptor |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARTN | artemin |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ASPH | aspartate beta-hydroxylase |
| ATN1 | atrophin 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK20 | cyclin-dependent kinase 20 |
| CLGN | calmegin |
| COL1A1 | collagen, type I, alpha 1 |
| CTBP2 | C-terminal binding protein 2 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOK5 | docking protein 5 |
| DVL2 | dishevelled segment polarity protein 2 |
| DYSF | dysferlin |
| EDA | ectodysplasin A |
| EFNB3 | ephrin-B3 |
| FCMR | Fc fragment of IgM receptor |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FHL1 | four and a half LIM domains 1 |
| FLJ22184 | |
| GK | glycerol kinase |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 |
| GSPT1 | G1 to S phase transition 1 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| LIMK1 | LIM domain kinase 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRRC6 | leucine rich repeat containing 6 |
| MAL | mal, T-cell differentiation protein |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NLRX1 | NLR family member X1 |
| OMG | oligodendrocyte myelin glycoprotein |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCDH1 | protocadherin 1 |
| PCDHB13 | protocadherin beta 13 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PLAC4 | placenta-specific 4 |
| POLL | polymerase (DNA directed), lambda |
| POU2F2 | POU class 2 homeobox 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTHLH | parathyroid hormone-like hormone |
| PTK6 | protein tyrosine kinase 6 |
| RAI2 | retinoic acid induced 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RGS12 | regulator of G-protein signaling 12 |
| RUNX1 | runt-related transcription factor 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH2D3A | SH2 domain containing 3A |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIRT5 | sirtuin 5 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STIM1 | stromal interaction molecule 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPMT | thiopurine S-methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| TYRP1 | tyrosinase-related protein 1 |
| UROD | uroporphyrinogen decarboxylase |
| VIM | vimentin |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZNF419 | zinc finger protein 419 |
| ZNF783 | zinc finger family member 783 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| ZW10 | zw10 kinetochore protein |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARMC7 | armadillo repeat containing 7 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC25 | coiled-coil domain containing 25 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFD | complement factor D (adipsin) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CORO1A | coronin, actin binding protein, 1A |
| CORT | cortistatin |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DSCAM | Down syndrome cell adhesion molecule |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4D | histone cluster 1, H4d |
| HOXA4 | homeobox A4 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IQCG | IQ motif containing G |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JUNB | jun B proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIF13B | kinesin family member 13B |
| LMAN1 | lectin, mannose-binding, 1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MED9 | mediator complex subunit 9 |
| METTL16 | methyltransferase like 16 |
| MYO1F | myosin IF |
| NEK11 | NIMA-related kinase 11 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PCDHA6 | protocadherin alpha 6 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PGP | phosphoglycolate phosphatase |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB17 | RAB17, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPGRIP1L | RPGRIP1-like |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SIX1 | SIX homeobox 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THOP1 | thimet oligopeptidase 1 |
| TMEM39B | transmembrane protein 39B |
| TNS2 | tensin 2 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VEGFC | vascular endothelial growth factor C |
| ZNF446 | zinc finger protein 446 |
| ZNF747 | zinc finger protein 747 |
