| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the LY-294002-5224 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| BBC3 | BCL2 binding component 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CCNG2 | cyclin G2 |
| CDK13 | cyclin-dependent kinase 13 |
| CDK19 | cyclin-dependent kinase 19 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTH | cystathionine gamma-lyase |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FLOT1 | flotillin 1 |
| GAS2 | growth arrest-specific 2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPR143 | G protein-coupled receptor 143 |
| GRB7 | growth factor receptor-bound protein 7 |
| HBP1 | HMG-box transcription factor 1 |
| HDAC5 | histone deacetylase 5 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3B | histone cluster 1, H3b |
| HIST2H2BE | histone cluster 2, H2be |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IBSP | integrin-binding sialoprotein |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ING4 | inhibitor of growth family, member 4 |
| IRS2 | insulin receptor substrate 2 |
| KIAA0430 | KIAA0430 |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LEPR | leptin receptor |
| LIMK1 | LIM domain kinase 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MXD4 | MAX dimerization protein 4 |
| NEBL | nebulette |
| NLRX1 | NLR family member X1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP88 | nucleoporin 88kDa |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PINK1 | PTEN induced putative kinase 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| S100A13 | S100 calcium binding protein A13 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD3 | SMAD family member 3 |
| SMIM14 | small integral membrane protein 14 |
| SMYD2 | SET and MYND domain containing 2 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STON1 | stonin 1 |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFF2 | trefoil factor 2 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TREX1 | three prime repair exonuclease 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSPAN2 | tetraspanin 2 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBA3C | tubulin, alpha 3c |
| TXNIP | thioredoxin interacting protein |
| WDR19 | WD repeat domain 19 |
| WDR33 | WD repeat domain 33 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XDH | xanthine dehydrogenase |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF493 | zinc finger protein 493 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ADORA2B | adenosine A2b receptor |
| AEN | apoptosis enhancing nuclease |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALS2CL | ALS2 C-terminal like |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC86 | coiled-coil domain containing 86 |
| CCND3 | cyclin D3 |
| CCNJ | cyclin J |
| CCNO | cyclin O |
| CD82 | CD82 molecule |
| CDC25A | cell division cycle 25A |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLDN9 | claudin 9 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COPS7B | COP9 signalosome subunit 7B |
| CORO1A | coronin, actin binding protein, 1A |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EAF2 | ELL associated factor 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit |
| FPGS | folylpolyglutamate synthase |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAMT | guanidinoacetate N-methyltransferase |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HEATR3 | HEAT repeat containing 3 |
| HOXA4 | homeobox A4 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFRD1 | interferon-related developmental regulator 1 |
| IL17RB | interleukin 17 receptor B |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0125 | KIAA0125 |
| KLC2 | kinesin light chain 2 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MMP9 | matrix metallopeptidase 9 |
| MSX1 | msh homeobox 1 |
| MUC3A | mucin 3A, cell surface associated |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZK1 | PDZ domain containing 1 |
| PER3 | period circadian clock 3 |
| PGBD5 | piggyBac transposable element derived 5 |
| PGP | phosphoglycolate phosphatase |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAI14 | retinoic acid induced 14 |
| RBM38 | RNA binding motif protein 38 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A9 | S100 calcium binding protein A9 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPHK1 | sphingosine kinase 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TMEM120B | transmembrane protein 120B |
| TMEM180 | transmembrane protein 180 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF787 | zinc finger protein 787 |
