| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the LY-294002-5576 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADD2 | adducin 2 (beta) |
| AIM2 | absent in melanoma 2 |
| ATN1 | atrophin 1 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BGN | biglycan |
| BLNK | B-cell linker |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA1 | carbonic anhydrase I |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCNK | cyclin K |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFAP70 | cilia and flagella associated protein 70 |
| COL6A2 | collagen, type VI, alpha 2 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DEFA4 | defensin, alpha 4, corticostatin |
| DFNA5 | deafness, autosomal dominant 5 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DMTN | dematin actin binding protein |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DOK4 | docking protein 4 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DRD1 | dopamine receptor D1 |
| EDN2 | endothelin 2 |
| EMILIN2 | elastin microfibril interfacer 2 |
| EMX1 | empty spiracles homeobox 1 |
| EPX | eosinophil peroxidase |
| ESR1 | estrogen receptor 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FLT1 | fms-related tyrosine kinase 1 |
| FOXP3 | forkhead box P3 |
| FPR1 | formyl peptide receptor 1 |
| FRMD4B | FERM domain containing 4B |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR85 | G protein-coupled receptor 85 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST1H1T | histone cluster 1, H1t |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
| IDUA | iduronidase, alpha-L- |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNA14 | interferon, alpha 14 |
| ING2 | inhibitor of growth family, member 2 |
| ING4 | inhibitor of growth family, member 4 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KLK1 | kallikrein 1 |
| KLK13 | kallikrein-related peptidase 13 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LEFTY2 | left-right determination factor 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAK | male germ cell-associated kinase |
| MAP1A | microtubule-associated protein 1A |
| MAPK7 | mitogen-activated protein kinase 7 |
| MFN2 | mitofusin 2 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NCKIPSD | NCK interacting protein with SH3 domain |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 |
| PHOX2A | paired-like homeobox 2a |
| PIGR | polymeric immunoglobulin receptor |
| PLXNA2 | plexin A2 |
| PMEL | premelanosome protein |
| PRAMEF12 | PRAME family member 12 |
| PRKCB | protein kinase C, beta |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC5A4 | solute carrier family 5 (glucose activated ion channel), member 4 |
| SPAG8 | sperm associated antigen 8 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SV2A | synaptic vesicle glycoprotein 2A |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMPRSS11D | transmembrane protease, serine 11D |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPM2 | tropomyosin 2 (beta) |
| TPMT | thiopurine S-methyltransferase |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TRBC1 | T cell receptor beta constant 1 |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| TSC22D2 | TSC22 domain family, member 2 |
| USP2 | ubiquitin specific peptidase 2 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL9 | B-cell CLL/lymphoma 9 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CA11 | carbonic anhydrase XI |
| CBX8 | chromobox homolog 8 |
| CCNL2 | cyclin L2 |
| CDKN2AIP | CDKN2A interacting protein |
| CENPB | centromere protein B, 80kDa |
| CHKB | choline kinase beta |
| CHMP6 | charged multivesicular body protein 6 |
| CLK1 | CDC-like kinase 1 |
| CLSTN2 | calsyntenin 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COG4 | component of oligomeric golgi complex 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 |
| CST6 | cystatin E/M |
| CUL7 | cullin 7 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNA3 | ephrin-A3 |
| ERCC5 | excision repair cross-complementation group 5 |
| FANCE | Fanconi anemia, complementation group E |
| FANCF | Fanconi anemia, complementation group F |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR87 | G protein-coupled receptor 87 |
| HDAC5 | histone deacetylase 5 |
| HOXA4 | homeobox A4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI35 | interferon-induced protein 35 |
| JMJD4 | jumonji domain containing 4 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KRT15 | keratin 15, type I |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBTD1 | mbt domain containing 1 |
| MCOLN1 | mucolipin 1 |
| MEX3C | mex-3 RNA binding family member C |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| NLRX1 | NLR family member X1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NXPH4 | neurexophilin 4 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PLA2G15 | phospholipase A2, group XV |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLL | polymerase (DNA directed), lambda |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRPH | peripherin |
| PRSS22 | protease, serine, 22 |
| PTDSS2 | phosphatidylserine synthase 2 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBL1 | retinoblastoma-like 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX5 | syntaxin 5 |
| TCTN2 | tectonic family member 2 |
| THOP1 | thimet oligopeptidase 1 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TPCN1 | two pore segment channel 1 |
| TWF2 | twinfilin actin binding protein 2 |
| VASH1 | vasohibin 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF16 | zinc finger protein 16 |
| ZNF184 | zinc finger protein 184 |
| ZNF250 | zinc finger protein 250 |
| ZNF329 | zinc finger protein 329 |
| ZNF74 | zinc finger protein 74 |
| ZNF83 | zinc finger protein 83 |
| ZNF862 | zinc finger protein 862 |
