| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the LY-294002-5587 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ART1 | ADP-ribosyltransferase 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP8A | bone morphogenetic protein 8a |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CALCR | calcitonin receptor |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CD58 | CD58 molecule |
| CDK12 | cyclin-dependent kinase 12 |
| CDK19 | cyclin-dependent kinase 19 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| COL1A1 | collagen, type I, alpha 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDO | D-aspartate oxidase |
| ECEL1 | endothelin converting enzyme-like 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPX | eosinophil peroxidase |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FFAR3 | free fatty acid receptor 3 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GRB7 | growth factor receptor-bound protein 7 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H3H | histone cluster 1, H3h |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFT27 | intraflagellar transport 27 |
| IL22 | interleukin 22 |
| ING4 | inhibitor of growth family, member 4 |
| IRS2 | insulin receptor substrate 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA0430 | KIAA0430 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL24 | kelch-like family member 24 |
| KRT2 | keratin 2, type II |
| KRT32 | keratin 32, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIF | leukemia inhibitory factor |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LPXN | leupaxin |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LYRM9 | LYR motif containing 9 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MIA3 | melanoma inhibitory activity family, member 3 |
| MXD3 | MAX dimerization protein 3 |
| MXD4 | MAX dimerization protein 4 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NOVA2 | neuro-oncological ventral antigen 2 |
| OLFM1 | olfactomedin 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PHF7 | PHD finger protein 7 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PRKCE | protein kinase C, epsilon |
| RECQL5 | RecQ protein-like 5 |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RXRB | retinoid X receptor, beta |
| SDS | serine dehydratase |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SNX1 | sorting nexin 1 |
| STON1 | stonin 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBX6 | T-box 6 |
| TLR8 | toll-like receptor 8 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TXNIP | thioredoxin interacting protein |
| UBXN1 | UBX domain protein 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF3 | zinc finger protein 3 |
| ZNF362 | zinc finger protein 362 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADORA2B | adenosine A2b receptor |
| ADRA2C | adrenoceptor alpha 2C |
| AEN | apoptosis enhancing nuclease |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP4 | bone morphogenetic protein 4 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNE1 | cyclin E1 |
| CCNO | cyclin O |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CORO1A | coronin, actin binding protein, 1A |
| CTPS1 | CTP synthase 1 |
| EGR3 | early growth response 3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM169A | family with sequence similarity 169, member A |
| FBXO22 | F-box protein 22 |
| FJX1 | four jointed box 1 (Drosophila) |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HEATR3 | HEAT repeat containing 3 |
| HIRA | histone cell cycle regulator |
| HOXA4 | homeobox A4 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL4R | interleukin 4 receptor |
| IRX4 | iroquois homeobox 4 |
| JMJD4 | jumonji domain containing 4 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0125 | KIAA0125 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP6D1 | MAP6 domain containing 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL2B | methyltransferase like 2B |
| MICALL2 | MICAL-like 2 |
| MIR22HG | MIR22 host gene |
| NES | nestin |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NXPH4 | neurexophilin 4 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PGBD5 | piggyBac transposable element derived 5 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PPAN | peter pan homolog (Drosophila) |
| PRMT7 | protein arginine methyltransferase 7 |
| PUS1 | pseudouridylate synthase 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RANBP6 | RAN binding protein 6 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF2 | ring finger protein 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SALL2 | spalt-like transcription factor 2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPHK1 | sphingosine kinase 1 |
| SUSD4 | sushi domain containing 4 |
| TARP | TCR gamma alternate reading frame protein |
| TBX19 | T-box 19 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM209 | transmembrane protein 209 |
| TMPRSS3 | transmembrane protease, serine 3 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZNF668 | zinc finger protein 668 |
