| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the LY-294002-5596 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| APAF1 | apoptotic peptidase activating factor 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC64 | coiled-coil domain containing 64 |
| CCNG2 | cyclin G2 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CDC25C | cell division cycle 25C |
| CDK13 | cyclin-dependent kinase 13 |
| CFAP70 | cilia and flagella associated protein 70 |
| CLDN17 | claudin 17 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| EPHB1 | EPH receptor B1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ESR1 | estrogen receptor 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBXO40 | F-box protein 40 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLS | glutaminase |
| GPR143 | G protein-coupled receptor 143 |
| GPR182 | G protein-coupled receptor 182 |
| GRB7 | growth factor receptor-bound protein 7 |
| HAMP | hepcidin antimicrobial peptide |
| HAS2 | hyaluronan synthase 2 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H3H | histone cluster 1, H3h |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IGLV4-60 | immunoglobulin lambda variable 4-60 |
| ING4 | inhibitor of growth family, member 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA0430 | KIAA0430 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LAT2 | linker for activation of T cells family, member 2 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LOXL2 | lysyl oxidase-like 2 |
| LYZL6 | lysozyme-like 6 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL7A | methyltransferase like 7A |
| MST1R | macrophage stimulating 1 receptor |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTSS1L | metastasis suppressor 1-like |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP3 | NEDD4 binding protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RAVER2 | ribonucleoprotein, PTB-binding 2 |
| RB1 | retinoblastoma 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC43A3 | solute carrier family 43, member 3 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPRR2B | small proline-rich protein 2B |
| SPTB | spectrin, beta, erythrocytic |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAB2 | stabilin 2 |
| STON1 | stonin 1 |
| SYN3 | synapsin III |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX15 | testis expressed 15 |
| TMEM8B | transmembrane protein 8B |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM10 | tripartite motif containing 10 |
| TXNIP | thioredoxin interacting protein |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| USP53 | ubiquitin specific peptidase 53 |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF3 | zinc finger protein 3 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADORA2B | adenosine A2b receptor |
| AEN | apoptosis enhancing nuclease |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5AR2 | complement component 5a receptor 2 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNO | cyclin O |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CORO1A | coronin, actin binding protein, 1A |
| CTPS1 | CTP synthase 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DBN1 | drebrin 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP8 | dual specificity phosphatase 8 |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| ELMO3 | engulfment and cell motility 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FAIM | Fas apoptotic inhibitory molecule |
| FAM169A | family with sequence similarity 169, member A |
| FAM57A | family with sequence similarity 57, member A |
| FCHO1 | FCH domain only 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HCFC2 | host cell factor C2 |
| HOXA4 | homeobox A4 |
| IFRD1 | interferon-related developmental regulator 1 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT15 | keratin 15, type I |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MALL | mal, T-cell differentiation protein-like |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MIR22HG | MIR22 host gene |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOCOS | molybdenum cofactor sulfurase |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPI | mannose phosphate isomerase |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NES | nestin |
| NLRX1 | NLR family member X1 |
| NOP2 | NOP2 nucleolar protein |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PER3 | period circadian clock 3 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLA2G3 | phospholipase A2, group III |
| PODXL2 | podocalyxin-like 2 |
| PP14571 | uncharacterized LOC100130449 |
| PPAN | peter pan homolog (Drosophila) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PUS1 | pseudouridylate synthase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAI14 | retinoic acid induced 14 |
| RGS19 | regulator of G-protein signaling 19 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUSD4 | sushi domain containing 4 |
| TARP | TCR gamma alternate reading frame protein |
| TMEM62 | transmembrane protein 62 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF219 | zinc finger protein 219 |
| ZNF668 | zinc finger protein 668 |
| ZNF696 | zinc finger protein 696 |
| ZNF804A | zinc finger protein 804A |
