| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the LY-294002-5599 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACRV1 | acrosomal vesicle protein 1 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADCK3 | aarF domain containing kinase 3 |
| ADCK4 | aarF domain containing kinase 4 |
| AIM2 | absent in melanoma 2 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ART1 | ADP-ribosyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP8A | bone morphogenetic protein 8a |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C5AR1 | complement component 5a receptor 1 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CALHM2 | calcium homeostasis modulator 2 |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CDK12 | cyclin-dependent kinase 12 |
| CDK19 | cyclin-dependent kinase 19 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CSF1R | colony stimulating factor 1 receptor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| EDNRA | endothelin receptor type A |
| EGR1 | early growth response 1 |
| EPHB1 | EPH receptor B1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBLN1 | fibulin 1 |
| GLS | glutaminase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GRB7 | growth factor receptor-bound protein 7 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3H | histone cluster 1, H3h |
| HIST2H2BE | histone cluster 2, H2be |
| HOXB5 | homeobox B5 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ING4 | inhibitor of growth family, member 4 |
| INSR | insulin receptor |
| IRS2 | insulin receptor substrate 2 |
| JAK3 | Janus kinase 3 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLHL24 | kelch-like family member 24 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LEPR | leptin receptor |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPXN | leupaxin |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIA3 | melanoma inhibitory activity family, member 3 |
| MXD3 | MAX dimerization protein 3 |
| MXD4 | MAX dimerization protein 4 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| N4BP3 | NEDD4 binding protein 3 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OLFM1 | olfactomedin 1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAX8 | paired box 8 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PML | promyelocytic leukemia |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRDM14 | PR domain containing 14 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| STON1 | stonin 1 |
| TBX6 | T-box 6 |
| TREX1 | three prime repair exonuclease 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| TXNIP | thioredoxin interacting protein |
| VGLL3 | vestigial-like family member 3 |
| VPRBP | Vpr (HIV-1) binding protein |
| WDR59 | WD repeat domain 59 |
| YPEL1 | yippee-like 1 (Drosophila) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF10 | zinc finger protein 10 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ADORA2B | adenosine A2b receptor |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARMC6 | armadillo repeat containing 6 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNJ | cyclin J |
| CCNO | cyclin O |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN9 | claudin 9 |
| CLSTN2 | calsyntenin 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHOD1 | formin homology 2 domain containing 1 |
| FOSL1 | FOS-like antigen 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HDAC4 | histone deacetylase 4 |
| HIRA | histone cell cycle regulator |
| HOXA4 | homeobox A4 |
| HOXB2 | homeobox B2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFRD1 | interferon-related developmental regulator 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IQCG | IQ motif containing G |
| IRX4 | iroquois homeobox 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0125 | KIAA0125 |
| KRT15 | keratin 15, type I |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC61 | leucine rich repeat containing 61 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAGEF1 | melanoma antigen family F1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MSX1 | msh homeobox 1 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOP2 | NOP2 nucleolar protein |
| ONECUT2 | one cut homeobox 2 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PER3 | period circadian clock 3 |
| PHF10 | PHD finger protein 10 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMM2 | phosphomannomutase 2 |
| PUS1 | pseudouridylate synthase 1 |
| RAI14 | retinoic acid induced 14 |
| RFPL3 | ret finger protein-like 3 |
| RNF121 | ring finger protein 121 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A9 | S100 calcium binding protein A9 |
| SDC3 | syndecan 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPHK1 | sphingosine kinase 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TMEM62 | transmembrane protein 62 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TWISTNB | TWIST neighbor |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR4 | WD repeat domain 4 |
| WLS | wntless Wnt ligand secretion mediator |
| XYLT2 | xylosyltransferase II |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF205 | zinc finger protein 205 |
| ZNF324 | zinc finger protein 324 |
| ZNF573 | zinc finger protein 573 |
| ZNF574 | zinc finger protein 574 |
| ZNF668 | zinc finger protein 668 |
| ZNF787 | zinc finger protein 787 |
