| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the LY-294002-5942 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKRD36 | ankyrin repeat domain 36 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOC1 | apolipoprotein C-I |
| AURKA | aurora kinase A |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BCL6 | B-cell CLL/lymphoma 6 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BMP1 | bone morphogenetic protein 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CDK13 | cyclin-dependent kinase 13 |
| CEP135 | centrosomal protein 135kDa |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CPT2 | carnitine palmitoyltransferase 2 |
| DCN | decorin |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DENND3 | DENN/MADD domain containing 3 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| EML3 | echinoderm microtubule associated protein like 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| GAREM | GRB2 associated, regulator of MAPK1 |
| HBP1 | HMG-box transcription factor 1 |
| HDLBP | high density lipoprotein binding protein |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST2H2BE | histone cluster 2, H2be |
| HIST3H2A | histone cluster 3, H2a |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IFT54 | intraflagellar transport 54 |
| IL17RB | interleukin 17 receptor B |
| INADL | InaD-like (Drosophila) |
| IRS2 | insulin receptor substrate 2 |
| ITGA7 | integrin, alpha 7 |
| JRK | Jrk homolog (mouse) |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAP7 | microtubule-associated protein 7 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBTD1 | mbt domain containing 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MXD4 | MAX dimerization protein 4 |
| NF1 | neurofibromin 1 |
| NMT2 | N-myristoyltransferase 2 |
| NNMT | nicotinamide N-methyltransferase |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PELO | pelota homolog (Drosophila) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| RGS12 | regulator of G-protein signaling 12 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SFTPB | surfactant protein B |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| STON1 | stonin 1 |
| TESK2 | testis-specific kinase 2 |
| TEX261 | testis expressed 261 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIGD6 | tigger transposable element derived 6 |
| TK2 | thymidine kinase 2, mitochondrial |
| TLE2 | transducin-like enhancer of split 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMSB15A | thymosin beta 15a |
| TROVE2 | TROVE domain family, member 2 |
| TXNRD3 | thioredoxin reductase 3 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WIZ | widely interspaced zinc finger motifs |
| WWOX | WW domain containing oxidoreductase |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZFHX3 | zinc finger homeobox 3 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF667 | zinc finger protein 667 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADORA2B | adenosine A2b receptor |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BAG2 | BCL2-associated athanogene 2 |
| BDNF | brain-derived neurotrophic factor |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC86 | coiled-coil domain containing 86 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDC6 | cell division cycle 6 |
| CENPJ | centromere protein J |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOLK | dolichol kinase |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EN1 | engrailed homeobox 1 |
| EN2 | engrailed homeobox 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPR39 | G protein-coupled receptor 39 |
| GPR85 | G protein-coupled receptor 85 |
| HAS2 | hyaluronan synthase 2 |
| HIST1H3A | histone cluster 1, H3a |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA1 | homeobox A1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB8 | heat shock 22kDa protein 8 |
| IL7R | interleukin 7 receptor |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIRREL | kin of IRRE like (Drosophila) |
| KRT34 | keratin 34, type I |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MCRS1 | microspherule protein 1 |
| MDFI | MyoD family inhibitor |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OSR2 | odd-skipped related transciption factor 2 |
| OXTR | oxytocin receptor |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PALMD | palmdelphin |
| PER3 | period circadian clock 3 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PRAME | preferentially expressed antigen in melanoma |
| PRDM12 | PR domain containing 12 |
| PRR4 | proline rich 4 (lacrimal) |
| PUS1 | pseudouridylate synthase 1 |
| RINT1 | RAD50 interactor 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMYD5 | SMYD family member 5 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SYT13 | synaptotagmin XIII |
| TCTN2 | tectonic family member 2 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TIPIN | TIMELESS interacting protein |
| TMEM19 | transmembrane protein 19 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM21 | tripartite motif containing 21 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR18 | WD repeat domain 18 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF492 | zinc finger protein 492 |
| ZNF668 | zinc finger protein 668 |
| ZNF770 | zinc finger protein 770 |
