| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the LY-294002-5965 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BAIAP3 | BAI1-associated protein 3 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC85B | coiled-coil domain containing 85B |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CD58 | CD58 molecule |
| CDC25C | cell division cycle 25C |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CPQ | carboxypeptidase Q |
| CST4 | cystatin S |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCHS2 | dachsous cadherin-related 2 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DRD1 | dopamine receptor D1 |
| DRD2 | dopamine receptor D2 |
| ETV5 | ets variant 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPC1 | glypican 1 |
| GRB10 | growth factor receptor-bound protein 10 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HABP4 | hyaluronan binding protein 4 |
| HCG4B | HLA complex group 4B (non-protein coding) |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IBSP | integrin-binding sialoprotein |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL2 | interleukin 2 |
| IRS2 | insulin receptor substrate 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLHL24 | kelch-like family member 24 |
| LAMA4 | laminin, alpha 4 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LOC157562 | uncharacterized LOC157562 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK7 | mitogen-activated protein kinase 7 |
| MEF2D | myocyte enhancer factor 2D |
| METTL7A | methyltransferase like 7A |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MXD4 | MAX dimerization protein 4 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PROL1 | proline rich, lacrimal 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RGS14 | regulator of G-protein signaling 14 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIRT5 | sirtuin 5 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SMAD3 | SMAD family member 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STON1 | stonin 1 |
| SUSD5 | sushi domain containing 5 |
| TBX19 | T-box 19 |
| TEF | thyrotrophic embryonic factor |
| THPO | thrombopoietin |
| TLE4 | transducin-like enhancer of split 4 |
| TPMT | thiopurine S-methyltransferase |
| TPP1 | tripeptidyl peptidase I |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TREX1 | three prime repair exonuclease 1 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UPK3A | uroplakin 3A |
| WDR91 | WD repeat domain 91 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF134 | zinc finger protein 134 |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADCY7 | adenylate cyclase 7 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLIC3 | chloride intracellular channel 3 |
| CLSTN3 | calsyntenin 3 |
| CORO1A | coronin, actin binding protein, 1A |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DUSP2 | dual specificity phosphatase 2 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM169A | family with sequence similarity 169, member A |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HIST1H3I | histone cluster 1, H3i |
| HOXA4 | homeobox A4 |
| HPN | hepsin |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIAA0125 | KIAA0125 |
| KLHL28 | kelch-like family member 28 |
| LAD1 | ladinin 1 |
| LHX6 | LIM homeobox 6 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP7D1 | MAP7 domain containing 1 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MORN1 | MORN repeat containing 1 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MSX1 | msh homeobox 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOTCH1 | notch 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRSN2 | neurensin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OSMR | oncostatin M receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PORCN | porcupine homolog (Drosophila) |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SDC3 | syndecan 3 |
| SECTM1 | secreted and transmembrane 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPHK1 | sphingosine kinase 1 |
| TAGLN | transgelin |
| TBC1D17 | TBC1 domain family, member 17 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM180 | transmembrane protein 180 |
| TMEM242 | transmembrane protein 242 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TPSG1 | tryptase gamma 1 |
| TWF2 | twinfilin actin binding protein 2 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UBQLN4 | ubiquilin 4 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF573 | zinc finger protein 573 |
| ZNF696 | zinc finger protein 696 |
