| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.277897 |
| VCL | vinculin | 0.220055 |
| NRG1 | neuregulin 1 | 0.170365 |
| LSAMP | limbic system-associated membrane protein | 0.168843 |
| FMN1 | formin 1 | 0.151245 |
| EXT1 | exostosin glycosyltransferase 1 | 0.147953 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.126435 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.122863 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.120663 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.106495 |
| TLE4 | transducin-like enhancer of split 4 | 0.100219 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0970885 |
| SYT1 | synaptotagmin I | 0.0943249 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0852252 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0850885 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0818857 |
| KLHL13 | kelch-like family member 13 | 0.0754619 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0695296 |
| GLCCI1 | glucocorticoid induced 1 | 0.0690303 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0679977 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0674258 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.065501 |
| STK38L | serine/threonine kinase 38 like | 0.0653797 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0636827 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0629841 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0603976 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0600965 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0594148 |
| NREP | neuronal regeneration related protein | 0.0585446 |
| SIK2 | salt-inducible kinase 2 | 0.0578103 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0563121 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0556642 |
| PRKCA | protein kinase C, alpha | 0.0543101 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0533644 |
| PLPP1 | phospholipid phosphatase 1 | 0.0529541 |
| ANTXR1 | anthrax toxin receptor 1 | 0.052299 |
| MSI2 | musashi RNA-binding protein 2 | 0.0517047 |
| RNF213 | ring finger protein 213 | 0.0513986 |
| ZNF804A | zinc finger protein 804A | 0.0511348 |
| TPM1 | tropomyosin 1 (alpha) | 0.0505588 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0496062 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0473823 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.04637 |
| CADM2 | cell adhesion molecule 2 | 0.0462251 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0456163 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.044973 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0448502 |
| TPM4 | tropomyosin 4 | 0.0442598 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0442134 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0434814 |
| RIGI | RNA sensor RIG-I | 0.0434707 |
| FERMT2 | fermitin family member 2 | 0.0432504 |
| RAD51B | RAD51 paralog B | 0.0429412 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0412282 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0410194 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0408127 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0406577 |
| TCF12 | transcription factor 12 | 0.0405423 |
| VMP1 | vacuole membrane protein 1 | 0.0405406 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0394975 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0387112 |
| INTS6 | integrator complex subunit 6 | 0.0386165 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0385949 |
| SYNPO2 | synaptopodin 2 | 0.0385396 |
| MYO1E | myosin IE | 0.0377803 |
| FRMD4A | FERM domain containing 4A | 0.0377532 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0377359 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0377143 |
| COL3A1 | collagen, type III, alpha 1 | 0.0374992 |
| FHIT | fragile histidine triad | 0.0370214 |
| CRH | corticotropin releasing hormone | 0.0366368 |
| FAM107B | family with sequence similarity 107, member B | 0.0361857 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0361054 |
| KLF6 | Kruppel-like factor 6 | 0.0359833 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0358317 |
| SP100 | SP100 nuclear antigen | 0.0357065 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0356713 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0353907 |
| BPTF | bromodomain PHD finger transcription factor | 0.0352982 |
| HOMER1 | homer scaffolding protein 1 | 0.0350157 |
| GPC5 | glypican 5 | 0.0346215 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0345481 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0344555 |
| PDLIM5 | PDZ and LIM domain 5 | 0.033173 |
| DNM3 | dynamin 3 | 0.0320699 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0319577 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0319378 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0318769 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0315232 |
| MEIS2 | Meis homeobox 2 | 0.0312162 |
| SIK3 | SIK family kinase 3 | 0.0308362 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0306654 |
| EGR1 | early growth response 1 | 0.0304261 |
| COL4A2 | collagen, type IV, alpha 2 | 0.030425 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0303353 |
| DST | dystonin | 0.0303027 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0300818 |
| TRIB2 | tribbles pseudokinase 2 | 0.0296692 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0291857 |
| CUX1 | cut-like homeobox 1 | 0.0291811 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HELZ | helicase with zinc finger | -0.0624874 |
| FAM13A | family with sequence similarity 13, member A | -0.059037 |
| LPIN1 | lipin 1 | -0.0564899 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0488704 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0470292 |
| ZNF292 | zinc finger protein 292 | -0.0456484 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0449592 |
| OGA | O-GlcNAcase | -0.0445394 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0376073 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0360958 |
| CLTC | clathrin, heavy chain (Hc) | -0.0352128 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0340188 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0338252 |
| PKM | pyruvate kinase, muscle | -0.0337897 |
| CDC27 | cell division cycle 27 | -0.0315547 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0307719 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0304843 |
| GOLGA4 | golgin A4 | -0.0302673 |
| RPL38 | ribosomal protein L38 | -0.0292771 |
| WDR45B | WD repeat domain 45B | -0.0292108 |
| RTN4 | reticulon 4 | -0.0292077 |
| NDRG1 | N-myc downstream regulated 1 | -0.0288099 |
| PTMA | prothymosin, alpha | -0.028801 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0286239 |
| SPAG9 | sperm associated antigen 9 | -0.0281121 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0259033 |
| XPO1 | exportin 1 | -0.0256115 |
| SUCO | SUN domain containing ossification factor | -0.0255398 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0254388 |
| NEK7 | NIMA-related kinase 7 | -0.0251273 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0248039 |
| PCM1 | pericentriolar material 1 | -0.0244257 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0237105 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0226915 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0226253 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0222176 |
| USP3 | ubiquitin specific peptidase 3 | -0.0221694 |
| RNF145 | ring finger protein 145 | -0.0220947 |
| RPS2 | ribosomal protein S2 | -0.0220784 |
| HMGB2 | high mobility group box 2 | -0.021769 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0217612 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0214928 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0209473 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0208353 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0207163 |
| NKTR | natural killer cell triggering receptor | -0.0204882 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0204234 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0201089 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0200824 |
| CASC3 | cancer susceptibility candidate 3 | -0.0197798 |
| SLMAP | sarcolemma associated protein | -0.0197106 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0195908 |
| S100A6 | S100 calcium binding protein A6 | -0.0195159 |
| NOP58 | NOP58 ribonucleoprotein | -0.0192668 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0191993 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0189172 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0189111 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0188762 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0187791 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0187367 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0187269 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0184212 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0183621 |
| MATR3 | matrin 3 | -0.018315 |
| KCTD3 | potassium channel tetramerization domain containing 3 | -0.0181055 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0180727 |
| RLF | rearranged L-myc fusion | -0.0179557 |
| FOXK2 | forkhead box K2 | -0.017879 |
| FNBP1 | formin binding protein 1 | -0.0178549 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0172579 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0172345 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.017079 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0170288 |
| TMSB10 | thymosin beta 10 | -0.0170252 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0170151 |
| NUP58 | nucleoporin 58 | -0.0169253 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0168441 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0168424 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.016786 |
| SETD5 | SET domain containing 5 | -0.0167811 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.016764 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0167579 |
| LMNA | lamin A/C | -0.0167332 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.0167208 |
| ZNF207 | zinc finger protein 207 | -0.0165727 |
| RPLP1 | ribosomal protein, large, P1 | -0.0165596 |
| PHIP | pleckstrin homology domain interacting protein | -0.0165278 |
| SQSTM1 | sequestosome 1 | -0.0165143 |
| SEPTIN7 | septin 7 | -0.0164099 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0163941 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0163311 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0162054 |
| RNF24 | ring finger protein 24 | -0.0161683 |
| MIS18BP1 | MIS18 binding protein 1 | -0.016144 |
| COG5 | component of oligomeric golgi complex 5 | -0.0161217 |
| CCND1 | cyclin D1 | -0.0159536 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0159201 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0158549 |
| SRP54 | signal recognition particle 54kDa | -0.0157091 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0156328 |
