| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2A | myocyte enhancer factor 2A | 0.0816868 |
| CLU | clusterin | 0.0761578 |
| MTSS1 | metastasis suppressor 1 | 0.060011 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0521167 |
| IGF2 | insulin-like growth factor 2 | 0.0514169 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0474225 |
| MT2A | metallothionein 2A | 0.0472447 |
| B2M | beta-2-microglobulin | 0.0467257 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0423024 |
| SQLE | squalene epoxidase | 0.0407453 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0373509 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0361975 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0353746 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0347986 |
| RAI14 | retinoic acid induced 14 | 0.0341647 |
| ARRDC3 | arrestin domain containing 3 | 0.0331489 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0327908 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0322286 |
| BARX2 | BARX homeobox 2 | 0.0321703 |
| TGM2 | transglutaminase 2 | 0.0319495 |
| GOLGA4 | golgin A4 | 0.0319011 |
| RPS8 | ribosomal protein S8 | 0.0318928 |
| SLK | STE20-like kinase | 0.0308279 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0301872 |
| TMF1 | TATA element modulatory factor 1 | 0.0300632 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0294184 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0293235 |
| DSTN | destrin (actin depolymerizing factor) | 0.0290354 |
| RPS4X | ribosomal protein S4, X-linked | 0.0287832 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0286755 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0285631 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0280697 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0279179 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0277898 |
| COG6 | component of oligomeric golgi complex 6 | 0.0263687 |
| PTK2 | protein tyrosine kinase 2 | 0.0258607 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0252899 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0244886 |
| TRAM1 | translocation associated membrane protein 1 | 0.0241425 |
| RPS6 | ribosomal protein S6 | 0.0241032 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.024045 |
| YBX1 | Y box binding protein 1 | 0.0237 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0235717 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0232826 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0231037 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0230052 |
| LDHA | lactate dehydrogenase A | 0.0228368 |
| MT1E | metallothionein 1E | 0.0226579 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0225308 |
| OPTN | optineurin | 0.0224105 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.022373 |
| LAMA5 | laminin, alpha 5 | 0.0221955 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0219699 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0218721 |
| SEPTIN9 | septin 9 | 0.0218657 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.021736 |
| SRP54 | signal recognition particle 54kDa | 0.0212815 |
| CD47 | CD47 molecule | 0.0208111 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0207525 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.020165 |
| COPA | coatomer protein complex, subunit alpha | 0.019905 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0198412 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0198231 |
| RPL21 | ribosomal protein L21 | 0.0197685 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0197012 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0196456 |
| ARF4 | ADP-ribosylation factor 4 | 0.0195108 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0195077 |
| BRD2 | bromodomain containing 2 | 0.0192769 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0191082 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0190487 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0190005 |
| FTL | ferritin, light polypeptide | 0.0189807 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0188417 |
| DSPP | dentin sialophosphoprotein | 0.0188151 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0187471 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.018547 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0185299 |
| ZNF654 | zinc finger protein 654 | 0.0183972 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0183042 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0182972 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0179363 |
| FNBP4 | formin binding protein 4 | 0.0179095 |
| CLTC | clathrin, heavy chain (Hc) | 0.0178928 |
| DSCAM | Down syndrome cell adhesion molecule | 0.017883 |
| FRMD6 | FERM domain containing 6 | 0.0177689 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0176541 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0176447 |
| LYST | lysosomal trafficking regulator | 0.0176412 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0174493 |
| YBX3 | Y box binding protein 3 | 0.0171088 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.017056 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0170182 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0169958 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0169285 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0169043 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0169036 |
| CDCP1 | CUB domain containing protein 1 | 0.0169032 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0168338 |
| PLPP1 | phospholipid phosphatase 1 | 0.0168303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.449354 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.221042 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.214088 |
| DPYD | dihydropyrimidine dehydrogenase | -0.164982 |
| AHNAK | AHNAK nucleoprotein | -0.146852 |
| SULF1 | sulfatase 1 | -0.123527 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.100095 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.082362 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0819366 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0783977 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0779069 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.077263 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0747799 |
| FN1 | fibronectin 1 | -0.0709167 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.070712 |
| TMSB4X | thymosin beta 4, X-linked | -0.064827 |
| FLNB | filamin B, beta | -0.0609032 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.059519 |
| RIGI | RNA sensor RIG-I | -0.0573813 |
| ACTN4 | actinin, alpha 4 | -0.0568988 |
| PDLIM5 | PDZ and LIM domain 5 | -0.056529 |
| MECOM | MDS1 and EVI1 complex locus | -0.0559042 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0549437 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0545976 |
| RASAL2 | RAS protein activator like 2 | -0.054408 |
| HMGA2 | high mobility group AT-hook 2 | -0.0542067 |
| SMYD3 | SET and MYND domain containing 3 | -0.054134 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0530628 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0529598 |
| C4BPB | complement component 4 binding protein, beta | -0.0527118 |
| RAD51B | RAD51 paralog B | -0.0522497 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0505718 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0494477 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0472374 |
| VCL | vinculin | -0.0462951 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0455709 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0449757 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0444937 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0439698 |
| CDK6 | cyclin-dependent kinase 6 | -0.0429377 |
| PRSS23 | protease, serine, 23 | -0.0423681 |
| CRACDL | CRACD like | -0.0422566 |
| MYO10 | myosin X | -0.0417441 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0416612 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0416345 |
| ACTG1 | actin gamma 1 | -0.0406614 |
| FRMD4B | FERM domain containing 4B | -0.0397471 |
| UTRN | utrophin | -0.0385749 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0385498 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0369907 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.036802 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0366954 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0363124 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0358468 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0356245 |
| DIAPH3 | diaphanous-related formin 3 | -0.034651 |
| KIAA1671 | KIAA1671 | -0.0346112 |
| MTAP | methylthioadenosine phosphorylase | -0.0338781 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0336418 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0328949 |
| FOXO1 | forkhead box O1 | -0.0328408 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0326942 |
| PGK1 | phosphoglycerate kinase 1 | -0.0323193 |
| PLEC | plectin | -0.0321522 |
| EFNA5 | ephrin-A5 | -0.0313572 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.031144 |
| FLNA | filamin A, alpha | -0.0305221 |
| GNAS | GNAS complex locus | -0.0304138 |
| TNS3 | tensin 3 | -0.0301377 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0298213 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0288962 |
| POTEF | POTE ankyrin domain family, member F | -0.0284291 |
| MYOF | myoferlin | -0.0279772 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0279351 |
| ARF1 | ADP-ribosylation factor 1 | -0.0276125 |
| S100A10 | S100 calcium binding protein A10 | -0.0273591 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0273252 |
| TENM4 | teneurin transmembrane protein 4 | -0.0272552 |
| FSTL1 | follistatin-like 1 | -0.0271748 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0271219 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0270291 |
| RGS4 | regulator of G-protein signaling 4 | -0.0269606 |
| ACTN1 | actinin, alpha 1 | -0.0264174 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0263875 |
| SULF2 | sulfatase 2 | -0.0263427 |
| RPS24 | ribosomal protein S24 | -0.0261982 |
| PALLD | palladin, cytoskeletal associated protein | -0.0259548 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0259545 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0256986 |
| CAVIN1 | caveolae associated protein 1 | -0.0255241 |
| RUNX1 | runt-related transcription factor 1 | -0.025469 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0254459 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0254325 |
| ZNF217 | zinc finger protein 217 | -0.0253905 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0253271 |
| AGMO | alkylglycerol monooxygenase | -0.024817 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0246935 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0244049 |
| ANLN | anillin, actin binding protein | -0.024315 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0242958 |
