| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0441402 |
| GOLGB1 | golgin B1 | 0.0254498 |
| FTL | ferritin, light polypeptide | 0.0251739 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0248406 |
| INTS6 | integrator complex subunit 6 | 0.0215966 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0211477 |
| RPS3 | ribosomal protein S3 | 0.0210838 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0199388 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0198006 |
| NDRG1 | N-myc downstream regulated 1 | 0.0196933 |
| GOLGA4 | golgin A4 | 0.0194063 |
| EMP1 | epithelial membrane protein 1 | 0.0193719 |
| DSTN | destrin (actin depolymerizing factor) | 0.0190875 |
| RBM39 | RNA binding motif protein 39 | 0.0179876 |
| RPS6 | ribosomal protein S6 | 0.0178429 |
| LDHA | lactate dehydrogenase A | 0.0174309 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0172021 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0169026 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0167555 |
| LMO7 | LIM domain 7 | 0.0164738 |
| HM13 | histocompatibility (minor) 13 | 0.0163154 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0162174 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0160775 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0154402 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0147808 |
| ANXA1 | annexin A1 | 0.0145259 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0134388 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0131836 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0129158 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0128814 |
| KLHL29 | kelch-like family member 29 | 0.0127641 |
| ATXN1 | ataxin 1 | 0.0125058 |
| AREG | amphiregulin | 0.0123499 |
| TMF1 | TATA element modulatory factor 1 | 0.0121547 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0120345 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0120229 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0119413 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.011881 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0118355 |
| AGR2 | anterior gradient 2 | 0.0116137 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0113159 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0112835 |
| MTDH | metadherin | 0.0112609 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0112323 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.011215 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0111456 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0111325 |
| RPS8 | ribosomal protein S8 | 0.0108855 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0107793 |
| ASPH | aspartate beta-hydroxylase | 0.0105814 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0104143 |
| RPL9 | ribosomal protein L9 | 0.010375 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0103574 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0102825 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0101432 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0100132 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0100115 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.00989323 |
| HKDC1 | hexokinase domain containing 1 | 0.00988296 |
| RPL37A | ribosomal protein L37a | 0.00973829 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00970166 |
| PGM3 | phosphoglucomutase 3 | 0.00967032 |
| FRMD5 | FERM domain containing 5 | 0.00956364 |
| ARF4 | ADP-ribosylation factor 4 | 0.00954467 |
| VEGFA | vascular endothelial growth factor A | 0.00952751 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00950536 |
| SCFD1 | sec1 family domain containing 1 | 0.00943848 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00942682 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00933425 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00931413 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00930249 |
| USP53 | ubiquitin specific peptidase 53 | 0.00921274 |
| POF1B | premature ovarian failure, 1B | 0.00920748 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0091616 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00896804 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.00890703 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00878679 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00871512 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00847458 |
| USP8 | ubiquitin specific peptidase 8 | 0.00845971 |
| TES | testin LIM domain protein | 0.00838043 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00834953 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00830171 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00828713 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00826671 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00826301 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.00824488 |
| SMIM14 | small integral membrane protein 14 | 0.00824037 |
| HYOU1 | hypoxia up-regulated 1 | 0.00817818 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00813749 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0080618 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.00789908 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00787898 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0078716 |
| PTMA | prothymosin, alpha | 0.00785392 |
| RPL7A | ribosomal protein L7a | 0.00782076 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.00773629 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00773355 |
| LMNA | lamin A/C | 0.00770561 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00761579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0540453 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0512099 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0421842 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0307691 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0233685 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0228467 |
| PRSS3 | protease, serine, 3 | -0.0224701 |
| PLSCR1 | phospholipid scramblase 1 | -0.022062 |
| H1-0 | H1.0 linker histone | -0.0201639 |
| POTEF | POTE ankyrin domain family, member F | -0.0198962 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0194394 |
| ACTN4 | actinin, alpha 4 | -0.0190577 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0187557 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0185889 |
| RNF213 | ring finger protein 213 | -0.0175299 |
| GPX2 | glutathione peroxidase 2 | -0.0171617 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0170905 |
| NPSR1 | neuropeptide S receptor 1 | -0.0170152 |
| TMSB10 | thymosin beta 10 | -0.0169644 |
| S100A10 | S100 calcium binding protein A10 | -0.0164322 |
| ETV6 | ets variant 6 | -0.0160496 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0154632 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0152442 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0152024 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0150406 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.015006 |
| ECT2 | epithelial cell transforming 2 | -0.0147463 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0142664 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0142158 |
| ETNK1 | ethanolamine kinase 1 | -0.0141725 |
| S100A6 | S100 calcium binding protein A6 | -0.0140921 |
| AHNAK | AHNAK nucleoprotein | -0.0140178 |
| WWC1 | WW and C2 domain containing 1 | -0.0139231 |
| BCL2L1 | BCL2-like 1 | -0.0137321 |
| MUC17 | mucin 17, cell surface associated | -0.0136521 |
| COBL | cordon-bleu WH2 repeat protein | -0.0132163 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0132034 |
| EGR1 | early growth response 1 | -0.0129203 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0128493 |
| MKI67 | marker of proliferation Ki-67 | -0.0124586 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0123857 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0122997 |
| STK24 | serine/threonine kinase 24 | -0.0122872 |
| SULF2 | sulfatase 2 | -0.0121453 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0119093 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0116819 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0116588 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0115378 |
| KRT8 | keratin 8, type II | -0.0115305 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0114674 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0113734 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0113126 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0111894 |
| KRT18 | keratin 18, type I | -0.0111206 |
| EZR | ezrin | -0.0110488 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0109798 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0109781 |
| NEK7 | NIMA-related kinase 7 | -0.0108227 |
| RPLP1 | ribosomal protein, large, P1 | -0.0106683 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0105667 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0105554 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0104888 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0103626 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0102803 |
| ITGB4 | integrin, beta 4 | -0.0102648 |
| PRKCA | protein kinase C, alpha | -0.0102417 |
| INSIG1 | insulin induced gene 1 | -0.0102222 |
| LAMA4 | laminin, alpha 4 | -0.0101267 |
| MSI2 | musashi RNA-binding protein 2 | -0.0100983 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0100481 |
| ABLIM1 | actin binding LIM protein 1 | -0.0100367 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0100347 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0100172 |
| HLA-E | major histocompatibility complex, class I, E | -0.00996085 |
| ABHD2 | abhydrolase domain containing 2 | -0.00978558 |
| RRBP1 | ribosome binding protein 1 | -0.00976095 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00975512 |
| SHROOM3 | shroom family member 3 | -0.00972808 |
| TNRC18 | trinucleotide repeat containing 18 | -0.009718 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00957966 |
| MX2 | MX dynamin-like GTPase 2 | -0.00956969 |
| RAD21 | RAD21 homolog (S. pombe) | -0.00949506 |
| AOPEP | aminopeptidase O (putative) | -0.00944556 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00938421 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00933435 |
| TFRC | transferrin receptor | -0.00925364 |
| CD2AP | CD2-associated protein | -0.00924975 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00918521 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0091606 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00913327 |
| TMEM45B | transmembrane protein 45B | -0.00912646 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.00911446 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.00910002 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.00905419 |
| SPIDR | scaffolding protein involved in DNA repair | -0.00904962 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00903256 |
| RAB7A | RAB7A, member RAS oncogene family | -0.00903244 |
| ANLN | anillin, actin binding protein | -0.00900483 |
| USP6NL | USP6 N-terminal like | -0.00900164 |
| MECOM | MDS1 and EVI1 complex locus | -0.00899212 |
