| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the LY2090314_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0672358 |
| SMAD3 | SMAD family member 3 | 0.0647773 |
| PCBP2 | poly(rC) binding protein 2 | 0.0538552 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0486225 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0466432 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0384889 |
| RPS12 | ribosomal protein S12 | 0.0358658 |
| LDHA | lactate dehydrogenase A | 0.0347831 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0334096 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.032881 |
| INTS6 | integrator complex subunit 6 | 0.0328188 |
| ECE1 | endothelin converting enzyme 1 | 0.0323481 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0306466 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300973 |
| TGM2 | transglutaminase 2 | 0.0291654 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0276639 |
| RPS6 | ribosomal protein S6 | 0.0273473 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0266344 |
| VEGFA | vascular endothelial growth factor A | 0.0260525 |
| IFI44L | interferon-induced protein 44-like | 0.0256698 |
| PKM | pyruvate kinase, muscle | 0.0255281 |
| KYNU | kynureninase | 0.0247836 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0245727 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0240358 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0237992 |
| RPL37A | ribosomal protein L37a | 0.0222903 |
| RPS29 | ribosomal protein S29 | 0.0219929 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0213257 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0208942 |
| RPL5 | ribosomal protein L5 | 0.0207317 |
| RPS3 | ribosomal protein S3 | 0.0206503 |
| EFNA5 | ephrin-A5 | 0.0201833 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0194812 |
| BRD2 | bromodomain containing 2 | 0.0194598 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0193341 |
| RPL31 | ribosomal protein L31 | 0.0193104 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0192322 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0190686 |
| RUNX1 | runt-related transcription factor 1 | 0.0189822 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0186922 |
| ZNF638 | zinc finger protein 638 | 0.0182925 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0181469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0181049 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0177659 |
| RPL28 | ribosomal protein L28 | 0.0174563 |
| RPS23 | ribosomal protein S23 | 0.0173332 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0172525 |
| RPS8 | ribosomal protein S8 | 0.0168313 |
| EGFR | epidermal growth factor receptor | 0.0167788 |
| RPS2 | ribosomal protein S2 | 0.0165176 |
| LRRC49 | leucine rich repeat containing 49 | 0.0164376 |
| RPL11 | ribosomal protein L11 | 0.0163987 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0161944 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0159885 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0158742 |
| VMP1 | vacuole membrane protein 1 | 0.0158267 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0158252 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0158203 |
| RPS17 | ribosomal protein S17 | 0.0156862 |
| PNN | pinin, desmosome associated protein | 0.015409 |
| RPS27 | ribosomal protein S27 | 0.0151207 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0151193 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0147796 |
| OPTN | optineurin | 0.0147451 |
| SEPTIN9 | septin 9 | 0.0145192 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0144852 |
| ATF7 | activating transcription factor 7 | 0.0144849 |
| RPL7 | ribosomal protein L7 | 0.0144559 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0144119 |
| NAV2 | neuron navigator 2 | 0.0142301 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0141539 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0139628 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0138167 |
| RPL36 | ribosomal protein L36 | 0.0138119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.013776 |
| RPL23 | ribosomal protein L23 | 0.0134626 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0134064 |
| HDAC9 | histone deacetylase 9 | 0.0134046 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0133916 |
| SQSTM1 | sequestosome 1 | 0.0133032 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0131926 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0131387 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0130755 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0130708 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0130282 |
| RPS13 | ribosomal protein S13 | 0.0127363 |
| KIAA1217 | KIAA1217 | 0.012694 |
| MYO10 | myosin X | 0.0126322 |
| RPL9 | ribosomal protein L9 | 0.0124864 |
| RNF145 | ring finger protein 145 | 0.012447 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0124071 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0123242 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0122869 |
| CEP250 | centrosomal protein 250kDa | 0.0122277 |
| NEBL | nebulette | 0.0121432 |
| YBX1 | Y box binding protein 1 | 0.0121361 |
| CPNE1 | copine I | 0.0121296 |
| PGM3 | phosphoglucomutase 3 | 0.012083 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0120122 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0120104 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.159995 |
| FN1 | fibronectin 1 | -0.150116 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.115086 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.107554 |
| LOX | lysyl oxidase | -0.098523 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0878626 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0843495 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0843193 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0829431 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0762291 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0737265 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0672152 |
| S100A6 | S100 calcium binding protein A6 | -0.063306 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0609252 |
| OSMR | oncostatin M receptor | -0.060862 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0596712 |
| STC1 | stanniocalcin 1 | -0.0592389 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0590754 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.059049 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0588568 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0548021 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0545941 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0544272 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0540597 |
| CD44 | CD44 molecule (Indian blood group) | -0.0538997 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0529182 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0524317 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0521026 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0514014 |
| MEF2A | myocyte enhancer factor 2A | -0.050921 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0507796 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0491126 |
| TMSB4X | thymosin beta 4, X-linked | -0.0490182 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0454479 |
| PTMA | prothymosin, alpha | -0.0444243 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0431984 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0427033 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0413312 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0409562 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0406993 |
| SNX9 | sorting nexin 9 | -0.0405459 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.039976 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0399 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0389291 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0385976 |
| IER3 | immediate early response 3 | -0.0383083 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0382163 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0373211 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0371119 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0369811 |
| AHNAK | AHNAK nucleoprotein | -0.036849 |
| HMGA2 | high mobility group AT-hook 2 | -0.0359035 |
| THBD | thrombomodulin | -0.0354006 |
| NRG1 | neuregulin 1 | -0.0352876 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0344492 |
| ENOSF1 | enolase superfamily member 1 | -0.0342806 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0336226 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0335709 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0328175 |
| H1-0 | H1.0 linker histone | -0.0319423 |
| CLMP | CXADR-like membrane protein | -0.030738 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.030441 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0304339 |
| USP34 | ubiquitin specific peptidase 34 | -0.030171 |
| NF1 | neurofibromin 1 | -0.0301353 |
| CDK14 | cyclin-dependent kinase 14 | -0.0298125 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.029785 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0294012 |
| PLIN2 | perilipin 2 | -0.0291711 |
| CP | ceruloplasmin (ferroxidase) | -0.0290845 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0290634 |
| PRSS23 | protease, serine, 23 | -0.0290616 |
| CDH13 | cadherin 13 | -0.0289713 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0285276 |
| VIM | vimentin | -0.0285273 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0280763 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0277248 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0273678 |
| MTSS1 | metastasis suppressor 1 | -0.0273263 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0272818 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.026562 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0263515 |
| VRK2 | vaccinia related kinase 2 | -0.0263128 |
| EGR1 | early growth response 1 | -0.0262713 |
| NUMB | numb homolog (Drosophila) | -0.0262404 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0262033 |
| IL1B | interleukin 1, beta | -0.0259641 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0256668 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0254396 |
| TMEM131 | transmembrane protein 131 | -0.0251642 |
| GPC6 | glypican 6 | -0.0249758 |
| PRRX1 | paired related homeobox 1 | -0.0247381 |
| HAS2 | hyaluronan synthase 2 | -0.0244088 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0242922 |
| PCNX1 | pecanex 1 | -0.0240578 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0239737 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0237013 |
| PGK1 | phosphoglycerate kinase 1 | -0.0233513 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0232183 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0231419 |
