| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.129624 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.10385 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.102627 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0892887 |
| POTEF | POTE ankyrin domain family, member F | 0.0708954 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0698581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0687055 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0643631 |
| DTNA | dystrobrevin, alpha | 0.0630298 |
| EFNA5 | ephrin-A5 | 0.0614688 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0567884 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0567615 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.055568 |
| NDRG1 | N-myc downstream regulated 1 | 0.0554768 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0545644 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0543227 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0525866 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.052545 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0512719 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0512628 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0506845 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0506579 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0506408 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0502002 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.049263 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0464948 |
| VGLL3 | vestigial-like family member 3 | 0.0461635 |
| BRD2 | bromodomain containing 2 | 0.0452701 |
| OCLN | occludin | 0.0447056 |
| SGMS2 | sphingomyelin synthase 2 | 0.0443258 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0441529 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0434627 |
| GOLGB1 | golgin B1 | 0.0427483 |
| TJP1 | tight junction protein 1 | 0.0426282 |
| FNIP1 | folliculin interacting protein 1 | 0.0421985 |
| PTK2 | protein tyrosine kinase 2 | 0.0411466 |
| MSN | moesin | 0.0408535 |
| MCL1 | myeloid cell leukemia 1 | 0.0398083 |
| SMAD3 | SMAD family member 3 | 0.0387971 |
| PCBP2 | poly(rC) binding protein 2 | 0.0384783 |
| HDAC9 | histone deacetylase 9 | 0.0382921 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0380329 |
| MYO1E | myosin IE | 0.0374829 |
| RPS12 | ribosomal protein S12 | 0.0369732 |
| VMP1 | vacuole membrane protein 1 | 0.0367162 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0366453 |
| CD44 | CD44 molecule (Indian blood group) | 0.0361827 |
| MYO5B | myosin VB | 0.0361783 |
| VEGFA | vascular endothelial growth factor A | 0.0359473 |
| INTS6 | integrator complex subunit 6 | 0.0353701 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0353221 |
| RPS2 | ribosomal protein S2 | 0.0348605 |
| RACK1 | receptor for activated C kinase 1 | 0.0346698 |
| KIAA1217 | KIAA1217 | 0.034555 |
| ERBIN | erbb2 interacting protein | 0.0333612 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0333202 |
| MED13 | mediator complex subunit 13 | 0.0331951 |
| EGR1 | early growth response 1 | 0.0329861 |
| ANO6 | anoctamin 6 | 0.0323667 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0322503 |
| TPM3 | tropomyosin 3 | 0.0321675 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.031599 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0314365 |
| ATXN1 | ataxin 1 | 0.0313604 |
| PALLD | palladin, cytoskeletal associated protein | 0.0311322 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0305504 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0301012 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0299381 |
| RUNX1 | runt-related transcription factor 1 | 0.0295029 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0293618 |
| RCOR1 | REST corepressor 1 | 0.0292117 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0291229 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0288115 |
| TUFT1 | tuftelin 1 | 0.0282651 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0280212 |
| GPHN | gephyrin | 0.0278945 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0278613 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0274397 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272865 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0271835 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0267792 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0265398 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0265244 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0261917 |
| DUSP10 | dual specificity phosphatase 10 | 0.0260347 |
| MYO10 | myosin X | 0.0259929 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0259388 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0259198 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0259184 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0256562 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0254917 |
| USP53 | ubiquitin specific peptidase 53 | 0.0253547 |
| NUP98 | nucleoporin 98kDa | 0.0252602 |
| RAB10 | RAB10, member RAS oncogene family | 0.0252157 |
| SEPTIN9 | septin 9 | 0.0251152 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0249762 |
| NAV2 | neuron navigator 2 | 0.0248716 |
| ZNF644 | zinc finger protein 644 | 0.024474 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0243922 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0242981 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.224287 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.175947 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.164727 |
| TMSB10 | thymosin beta 10 | -0.121257 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0988657 |
| TMSB4X | thymosin beta 4, X-linked | -0.0967169 |
| PGK1 | phosphoglycerate kinase 1 | -0.094606 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0943164 |
| FTL | ferritin, light polypeptide | -0.0872484 |
| S100A6 | S100 calcium binding protein A6 | -0.0871178 |
| S100A10 | S100 calcium binding protein A10 | -0.0775555 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0761428 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.073997 |
| TOP1 | topoisomerase (DNA) I | -0.0727005 |
| CD2AP | CD2-associated protein | -0.0639888 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0615234 |
| ASPH | aspartate beta-hydroxylase | -0.0598065 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0580798 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0574084 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0561708 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0546898 |
| HMGB2 | high mobility group box 2 | -0.0545788 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0541568 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0534847 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0533614 |
| TMEM123 | transmembrane protein 123 | -0.051281 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0505912 |
| LAMB3 | laminin, beta 3 | -0.0504803 |
| EPCAM | epithelial cell adhesion molecule | -0.0498502 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0496711 |
| GNAS | GNAS complex locus | -0.0493423 |
| FAM162A | family with sequence similarity 162, member A | -0.0485981 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0473453 |
| CCND1 | cyclin D1 | -0.0471743 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.04503 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0447411 |
| FAM13A | family with sequence similarity 13, member A | -0.0442932 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0438025 |
| UBC | ubiquitin C | -0.0434744 |
| PLAU | plasminogen activator, urokinase | -0.042759 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.042388 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0421468 |
| TSC22D2 | TSC22 domain family, member 2 | -0.041804 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0416432 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0413666 |
| TMEM263 | transmembrane protein 263 | -0.0405491 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0402539 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0399489 |
| TPM4 | tropomyosin 4 | -0.0399315 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0398776 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0390814 |
| LMO7 | LIM domain 7 | -0.037678 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0376543 |
| CSTB | cystatin B (stefin B) | -0.0375023 |
| CD63 | CD63 molecule | -0.0374042 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0372857 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0365517 |
| RPL35A | ribosomal protein L35a | -0.034912 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.034853 |
| ARF1 | ADP-ribosylation factor 1 | -0.0348276 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0342699 |
| ACTG1 | actin gamma 1 | -0.0340754 |
| CALU | calumenin | -0.0339027 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0333698 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0332386 |
| TPI1 | triosephosphate isomerase 1 | -0.0331705 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0328537 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0328193 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0323131 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.032185 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0321434 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0311198 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0309684 |
| QKI | QKI, KH domain containing, RNA binding | -0.0308754 |
| RHEB | Ras homolog enriched in brain | -0.0304492 |
| KRT18 | keratin 18, type I | -0.0304283 |
| G0S2 | G0/G1 switch 2 | -0.0303255 |
| HLA-A | major histocompatibility complex, class I, A | -0.0300221 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0298402 |
| AHNAK | AHNAK nucleoprotein | -0.0298352 |
| MT2A | metallothionein 2A | -0.0297749 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0297136 |
| H3-3B | H3.3 histone B | -0.0293338 |
| RPS24 | ribosomal protein S24 | -0.0292903 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0289216 |
| TFG | TRK-fused gene | -0.0287646 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0285914 |
| OGA | O-GlcNAcase | -0.0284371 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.028305 |
| ENO1 | enolase 1, (alpha) | -0.0283016 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0282684 |
| CALR | calreticulin | -0.0280307 |
| RRBP1 | ribosome binding protein 1 | -0.0277944 |
| ANLN | anillin, actin binding protein | -0.0276203 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0276098 |
| MORF4L1 | mortality factor 4 like 1 | -0.0275895 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0275155 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0273354 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.027319 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0272029 |
