| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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139 genes differentially expressed following the LY2090314_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.232192 |
| PDE10A | phosphodiesterase 10A | 0.18275 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.168463 |
| HMGA2 | high mobility group AT-hook 2 | 0.149045 |
| PTK2 | protein tyrosine kinase 2 | 0.103542 |
| ASPH | aspartate beta-hydroxylase | 0.102099 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.101603 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0990516 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0981966 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0959018 |
| NAV1 | neuron navigator 1 | 0.0945303 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0939417 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0716742 |
| CDH13 | cadherin 13 | 0.0701264 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0685087 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0628221 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0538401 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0519468 |
| GOLGA4 | golgin A4 | 0.0508944 |
| RPL19 | ribosomal protein L19 | 0.0495437 |
| LDHA | lactate dehydrogenase A | 0.0476276 |
| DST | dystonin | 0.0447346 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0444566 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0438003 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0436293 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0428063 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0404772 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0391979 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.038662 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0386091 |
| CADM2 | cell adhesion molecule 2 | 0.0383928 |
| INHBA | inhibin, beta A | 0.0358417 |
| WAC | WW domain containing adaptor with coiled-coil | 0.033557 |
| FTL | ferritin, light polypeptide | 0.0327273 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0310295 |
| USP34 | ubiquitin specific peptidase 34 | 0.0306047 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302909 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0301119 |
| SQSTM1 | sequestosome 1 | 0.0277454 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0274945 |
| JMJD1C | jumonji domain containing 1C | 0.0255701 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0251697 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0243547 |
| RPS3 | ribosomal protein S3 | 0.0221907 |
| NLGN1 | neuroligin 1 | 0.0173667 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.0161437 |
| RAD51B | RAD51 paralog B | 0.0158387 |
| ZNF292 | zinc finger protein 292 | 0.0154587 |
| SMYD3 | SET and MYND domain containing 3 | 0.0147915 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0137015 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0133887 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0132071 |
| ACTN4 | actinin, alpha 4 | 0.0115429 |
| RPS12 | ribosomal protein S12 | 0.0111773 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.010731 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0102206 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00943683 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00911335 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00827753 |
| SYT1 | synaptotagmin I | 0.00750916 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00680004 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0065296 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0055141 |
| CCNI | cyclin I | 0.00419496 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.00384689 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00377444 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.00288187 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00160297 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00159751 |
| PKM | pyruvate kinase, muscle | 8.01444E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.233627 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204938 |
| PTMA | prothymosin, alpha | -0.198564 |
| TMSB10 | thymosin beta 10 | -0.148601 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.108483 |
| EGFR | epidermal growth factor receptor | -0.0969453 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0953035 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0899794 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0876799 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0841894 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0777643 |
| ANXA2 | annexin A2 | -0.0771858 |
| UBC | ubiquitin C | -0.0753252 |
| RPS6 | ribosomal protein S6 | -0.0731984 |
| RPS27A | ribosomal protein S27a | -0.0633633 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.061262 |
| RPL23 | ribosomal protein L23 | -0.0565386 |
| CD44 | CD44 molecule (Indian blood group) | -0.0552796 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0552326 |
| LMO7 | LIM domain 7 | -0.0538726 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0520948 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.050549 |
| MYOF | myoferlin | -0.0431673 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0429555 |
| GPHN | gephyrin | -0.0422121 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.042131 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0417235 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0413565 |
| RLF | rearranged L-myc fusion | -0.0405656 |
| MED13L | mediator complex subunit 13-like | -0.0404146 |
| RTN4 | reticulon 4 | -0.0393035 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0373567 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0366785 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0363984 |
| PRKCA | protein kinase C, alpha | -0.0351832 |
| GPC6 | glypican 6 | -0.0348883 |
| NUP58 | nucleoporin 58 | -0.0345672 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0335129 |
| SLTM | SAFB-like, transcription modulator | -0.0322409 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.03088 |
| VIM | vimentin | -0.0307815 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0296065 |
| DOCK5 | dedicator of cytokinesis 5 | -0.029292 |
| ACTG1 | actin gamma 1 | -0.0290591 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0288676 |
| PARD3 | par-3 family cell polarity regulator | -0.0285922 |
| SRPK2 | SRSF protein kinase 2 | -0.0278371 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0273194 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0258984 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0256816 |
| EFNA5 | ephrin-A5 | -0.024695 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0211746 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0193916 |
| CUX1 | cut-like homeobox 1 | -0.0175549 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0165758 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0155064 |
| MYO1E | myosin IE | -0.0154247 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0152518 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0126532 |
| PGK1 | phosphoglycerate kinase 1 | -0.0115944 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0099679 |
| NDRG1 | N-myc downstream regulated 1 | -0.0092889 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00691074 |
| RPL31 | ribosomal protein L31 | -0.00479189 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.00409733 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00171847 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00126219 |
| SETD5 | SET domain containing 5 | -0.00101516 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -8.10937E-5 |
