| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.204042 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.17417 |
| FOXP1 | forkhead box P1 | 0.129807 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.109863 |
| HDAC9 | histone deacetylase 9 | 0.101894 |
| EGFR | epidermal growth factor receptor | 0.0998717 |
| VCL | vinculin | 0.0942808 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0879242 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0656994 |
| PKM | pyruvate kinase, muscle | 0.0652289 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0643685 |
| TJP1 | tight junction protein 1 | 0.0620222 |
| POTEF | POTE ankyrin domain family, member F | 0.0547473 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0480001 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.046776 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0461126 |
| GLI3 | GLI family zinc finger 3 | 0.0420924 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0390691 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0390564 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.038235 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0361724 |
| NBEA | neurobeachin | 0.035984 |
| MLIP | muscular LMNA-interacting protein | 0.0350152 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0336333 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0334102 |
| NAV2 | neuron navigator 2 | 0.0329126 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0324073 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0320712 |
| FER1L6 | fer-1-like family member 6 | 0.0319211 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0304241 |
| ATP13A3 | ATPase type 13A3 | 0.0302868 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0297387 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0291972 |
| TXNRD1 | thioredoxin reductase 1 | 0.0289881 |
| GSE1 | Gse1 coiled-coil protein | 0.0283672 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0282539 |
| RPS4X | ribosomal protein S4, X-linked | 0.0276264 |
| GLI2 | GLI family zinc finger 2 | 0.0275192 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0274802 |
| DUSP4 | dual specificity phosphatase 4 | 0.0272729 |
| MKI67 | marker of proliferation Ki-67 | 0.0266668 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0264525 |
| CEP112 | centrosomal protein 112kDa | 0.0263863 |
| CENPF | centromere protein F, 350/400kDa | 0.0261016 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0256154 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.025518 |
| ZNF438 | zinc finger protein 438 | 0.0246378 |
| ZNF608 | zinc finger protein 608 | 0.0246344 |
| PRELID2 | PRELI domain containing 2 | 0.0245935 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0244983 |
| MEIS2 | Meis homeobox 2 | 0.024324 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0242196 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.0241225 |
| RRM2 | ribonucleotide reductase M2 | 0.0239055 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0239021 |
| TOB1 | transducer of ERBB2, 1 | 0.0238194 |
| PDGFC | platelet derived growth factor C | 0.0234704 |
| FHIT | fragile histidine triad | 0.0226609 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0226546 |
| MACROD2 | MACRO domain containing 2 | 0.022059 |
| PARD3 | par-3 family cell polarity regulator | 0.0219036 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0218804 |
| PYGB | phosphorylase, glycogen; brain | 0.0215591 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0214207 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0214167 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0213868 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0212227 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0211743 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0209387 |
| PTMS | parathymosin | 0.020938 |
| KRIT1 | KRIT1, ankyrin repeat containing | 0.0208626 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0205408 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0201982 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0201918 |
| FBLN2 | fibulin 2 | 0.0200174 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0199843 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0199301 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0197833 |
| PDLIM5 | PDZ and LIM domain 5 | 0.019727 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0196744 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0196731 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.019606 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0194983 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0194408 |
| CUX1 | cut-like homeobox 1 | 0.0194191 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0193044 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0190262 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0189983 |
| LRRC7 | leucine rich repeat containing 7 | 0.0189438 |
| PDE7B | phosphodiesterase 7B | 0.018888 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0186699 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0185906 |
| CEP192 | centrosomal protein 192kDa | 0.0185876 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0184747 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0181966 |
| ITGA6 | integrin, alpha 6 | 0.0181605 |
| BRD2 | bromodomain containing 2 | 0.0181467 |
| TPX2 | TPX2, microtubule-associated | 0.0181352 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0180834 |
| CORO1C | coronin, actin binding protein, 1C | 0.0179807 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.163523 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.136654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133338 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10742 |
| TMSB4X | thymosin beta 4, X-linked | -0.093052 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0782114 |
| GOLGA4 | golgin A4 | -0.0592542 |
| PGK1 | phosphoglycerate kinase 1 | -0.0591631 |
| RPS6 | ribosomal protein S6 | -0.058973 |
| AHNAK | AHNAK nucleoprotein | -0.0547761 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0536281 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0487431 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0477808 |
| RBM39 | RNA binding motif protein 39 | -0.0452192 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0440982 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.044018 |
| RPL37A | ribosomal protein L37a | -0.0431716 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0425632 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0423254 |
| RPS8 | ribosomal protein S8 | -0.0410896 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0403345 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0402749 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0395909 |
| ACTG1 | actin gamma 1 | -0.0393572 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0381354 |
| RPL35A | ribosomal protein L35a | -0.037781 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0377125 |
| RPL12 | ribosomal protein L12 | -0.0374323 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.037047 |
| RPL31 | ribosomal protein L31 | -0.0370058 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0358362 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0349142 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0348613 |
| RLF | rearranged L-myc fusion | -0.0346469 |
| SQSTM1 | sequestosome 1 | -0.0343381 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0331225 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.03216 |
| RPS27A | ribosomal protein S27a | -0.0312965 |
| NCKAP1 | NCK-associated protein 1 | -0.0304507 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0300254 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0300118 |
| CANX | calnexin | -0.0299006 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0297068 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0294164 |
| COG5 | component of oligomeric golgi complex 5 | -0.0293178 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0291548 |
| S100A6 | S100 calcium binding protein A6 | -0.0287865 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0284534 |
| QKI | QKI, KH domain containing, RNA binding | -0.0279376 |
| RPS3 | ribosomal protein S3 | -0.0276808 |
| RPL26 | ribosomal protein L26 | -0.0270426 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0269477 |
| PRRC2C | proline-rich coiled-coil 2C | -0.026907 |
| SEC24D | SEC24 family member D | -0.0263314 |
| ANKRD12 | ankyrin repeat domain 12 | -0.026256 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0259925 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.025878 |
| EZR | ezrin | -0.0257481 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0255375 |
| SEPTIN7 | septin 7 | -0.02526 |
| MAP4 | microtubule-associated protein 4 | -0.0250213 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0249471 |
| ZNF106 | zinc finger protein 106 | -0.0245692 |
| KIAA1958 | KIAA1958 | -0.0243815 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0242235 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0240932 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0240727 |
| S100A10 | S100 calcium binding protein A10 | -0.0239324 |
| PHF3 | PHD finger protein 3 | -0.0236557 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0236189 |
| ZNF292 | zinc finger protein 292 | -0.0235724 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0234741 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0234354 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0232291 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0231875 |
| RPLP1 | ribosomal protein, large, P1 | -0.0231761 |
| RPL7A | ribosomal protein L7a | -0.023147 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0231215 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0229327 |
| SPAG9 | sperm associated antigen 9 | -0.0229262 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0229079 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.022807 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0227214 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0225747 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0222039 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0221497 |
| HM13 | histocompatibility (minor) 13 | -0.0220872 |
| TNRC6B | trinucleotide repeat containing 6B | -0.021877 |
| WDR45B | WD repeat domain 45B | -0.0218334 |
| XPO1 | exportin 1 | -0.0217532 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0215755 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0213445 |
| NUP58 | nucleoporin 58 | -0.0213027 |
| CCNI | cyclin I | -0.0212769 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0212096 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0211678 |
| SMAP1 | small ArfGAP 1 | -0.021082 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0209553 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.020735 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0206724 |
