| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.132034 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0769063 |
| FN1 | fibronectin 1 | 0.0707063 |
| CALD1 | caldesmon 1 | 0.0664297 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0603633 |
| PRELID2 | PRELI domain containing 2 | 0.0527888 |
| GLIS3 | GLIS family zinc finger 3 | 0.0520931 |
| CD44 | CD44 molecule (Indian blood group) | 0.0514906 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0492509 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.043068 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0416447 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0406364 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0388527 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0377024 |
| MEF2A | myocyte enhancer factor 2A | 0.0363216 |
| HMGA2 | high mobility group AT-hook 2 | 0.0355803 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0355014 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0343123 |
| ASPH | aspartate beta-hydroxylase | 0.0340162 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0340005 |
| SBF2 | SET binding factor 2 | 0.0338441 |
| EXOC4 | exocyst complex component 4 | 0.0325081 |
| INTS6 | integrator complex subunit 6 | 0.0322343 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0317365 |
| CLIC4 | chloride intracellular channel 4 | 0.0313144 |
| KYNU | kynureninase | 0.0311007 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0299752 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.02866 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0283969 |
| FAM20C | family with sequence similarity 20, member C | 0.0283596 |
| RAD51B | RAD51 paralog B | 0.0270752 |
| CLMP | CXADR-like membrane protein | 0.0257596 |
| NRXN3 | neurexin 3 | 0.0249589 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0249204 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0245915 |
| RUNX1 | runt-related transcription factor 1 | 0.0244081 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0233566 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0233512 |
| AUTS2 | autism susceptibility candidate 2 | 0.0232974 |
| TPM4 | tropomyosin 4 | 0.0232667 |
| WWOX | WW domain containing oxidoreductase | 0.0232643 |
| COG6 | component of oligomeric golgi complex 6 | 0.0230774 |
| ZNF638 | zinc finger protein 638 | 0.0229489 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0225341 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0216349 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0214989 |
| SP100 | SP100 nuclear antigen | 0.0214667 |
| GPATCH8 | G patch domain containing 8 | 0.0214592 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0212416 |
| ARHGAP10 | Rho GTPase activating protein 10 | 0.0212336 |
| SMYD3 | SET and MYND domain containing 3 | 0.0205031 |
| PRSS23 | protease, serine, 23 | 0.0204871 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0204801 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0202864 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0201834 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0201504 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.020058 |
| GOLGB1 | golgin B1 | 0.0200386 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0198403 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0197444 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0195139 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0192225 |
| SETBP1 | SET binding protein 1 | 0.0192024 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.0189448 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0188965 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0188955 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0188028 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0186078 |
| AOPEP | aminopeptidase O (putative) | 0.0186052 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0185227 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0184631 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0183553 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0183509 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0180129 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0179977 |
| PRKCA | protein kinase C, alpha | 0.0179972 |
| USO1 | USO1 vesicle transport factor | 0.0178784 |
| RBM6 | RNA binding motif protein 6 | 0.0178231 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0177948 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0176704 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0176057 |
| EHBP1 | EH domain binding protein 1 | 0.0175549 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0174749 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0172632 |
| TNS3 | tensin 3 | 0.0171733 |
| TANK | TRAF family member-associated NFKB activator | 0.0171202 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0170952 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0170908 |
| GALK2 | galactokinase 2 | 0.0170874 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0170503 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0169923 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0167862 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0167543 |
| ZNF395 | zinc finger protein 395 | 0.0167089 |
| PTK2 | protein tyrosine kinase 2 | 0.0166239 |
| PRMT2 | protein arginine methyltransferase 2 | 0.0165176 |
| VCL | vinculin | 0.0164752 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0163462 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0163119 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0161573 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.15987 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.12709 |
| COL1A2 | collagen, type I, alpha 2 | -0.0767807 |
| VIM | vimentin | -0.0738933 |
| TMSB10 | thymosin beta 10 | -0.0734822 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0636731 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.060101 |
| MT2A | metallothionein 2A | -0.0553977 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0535593 |
| B2M | beta-2-microglobulin | -0.0530116 |
| NDRG1 | N-myc downstream regulated 1 | -0.0507265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.046496 |
| LDHA | lactate dehydrogenase A | -0.044068 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0423969 |
| CALU | calumenin | -0.0420166 |
| GOLGA4 | golgin A4 | -0.041571 |
| LOX | lysyl oxidase | -0.0407106 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0393511 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0387556 |
| SDC4 | syndecan 4 | -0.0382951 |
| STC1 | stanniocalcin 1 | -0.0374044 |
| FTL | ferritin, light polypeptide | -0.037378 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0370481 |
| MAP1B | microtubule-associated protein 1B | -0.0370241 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.036751 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.035935 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0353387 |
| HLA-C | major histocompatibility complex, class I, C | -0.0341237 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0333063 |
| LOC112694756 | uncharaterized LOC112694756 | -0.03208 |
| TMEM165 | transmembrane protein 165 | -0.0292822 |
| RLF | rearranged L-myc fusion | -0.0288704 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0276674 |
| LAMB3 | laminin, beta 3 | -0.0266491 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0265185 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0264429 |
| COPA | coatomer protein complex, subunit alpha | -0.0258183 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0257793 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0255685 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0254715 |
| CANX | calnexin | -0.0250667 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0249266 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0247324 |
| TNPO3 | transportin 3 | -0.0243547 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0242992 |
| TFG | TRK-fused gene | -0.0241462 |
| ARF4 | ADP-ribosylation factor 4 | -0.0240236 |
| RHEB | Ras homolog enriched in brain | -0.0240086 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0236772 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0236619 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0235576 |
| PKM | pyruvate kinase, muscle | -0.0230899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0229682 |
| SPAG9 | sperm associated antigen 9 | -0.0229063 |
| PGK1 | phosphoglycerate kinase 1 | -0.0228105 |
| MT1X | metallothionein 1X | -0.0228042 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0228027 |
| CCNI | cyclin I | -0.0224678 |
| MKI67 | marker of proliferation Ki-67 | -0.0224309 |
| AHNAK | AHNAK nucleoprotein | -0.0222418 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.022231 |
| ATP13A3 | ATPase type 13A3 | -0.0221989 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0216617 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0216234 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0214645 |
| SMC4 | structural maintenance of chromosomes 4 | -0.021281 |
| SETD5 | SET domain containing 5 | -0.0206364 |
| UBC | ubiquitin C | -0.0202056 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0200827 |
| MSN | moesin | -0.0196635 |
| ARRDC3 | arrestin domain containing 3 | -0.0195864 |
| RNF145 | ring finger protein 145 | -0.0194573 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0193937 |
| CLINT1 | clathrin interactor 1 | -0.0193435 |
| TPI1 | triosephosphate isomerase 1 | -0.0191769 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0191673 |
| SERINC3 | serine incorporator 3 | -0.0191486 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0191419 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0190245 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0189406 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0187935 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0186981 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0184147 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0181319 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.018064 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0179118 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.0176785 |
| TPX2 | TPX2, microtubule-associated | -0.0176662 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0174684 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0173881 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0172968 |
| CD109 | CD109 molecule | -0.0171656 |
| SCFD2 | sec1 family domain containing 2 | -0.0171377 |
| PFN1 | profilin 1 | -0.0170801 |
| LMNA | lamin A/C | -0.0169894 |
| NBAS | neuroblastoma amplified sequence | -0.0169607 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0169479 |
| SRP54 | signal recognition particle 54kDa | -0.0169323 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0168679 |
| ANXA2 | annexin A2 | -0.0167614 |
