| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.122292 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.119116 |
| SVIL | supervillin | 0.0818286 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0717737 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0692476 |
| INTS6 | integrator complex subunit 6 | 0.0692408 |
| LDHA | lactate dehydrogenase A | 0.0623447 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0589411 |
| ANXA2 | annexin A2 | 0.0581571 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.057387 |
| VIM | vimentin | 0.0561421 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0560872 |
| EGR1 | early growth response 1 | 0.0526577 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0496273 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0482078 |
| FTL | ferritin, light polypeptide | 0.0478626 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0476659 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0467944 |
| EGFR | epidermal growth factor receptor | 0.0429529 |
| TMSB10 | thymosin beta 10 | 0.0427405 |
| ANGPTL4 | angiopoietin-like 4 | 0.0409357 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0406305 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0405397 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0403598 |
| ASPH | aspartate beta-hydroxylase | 0.0399663 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0394216 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0388013 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0387808 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037747 |
| IGF2 | insulin-like growth factor 2 | 0.0367625 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0356096 |
| CD44 | CD44 molecule (Indian blood group) | 0.034382 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0336244 |
| FMNL2 | formin-like 2 | 0.0335095 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0319086 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0317343 |
| HLA-B | major histocompatibility complex, class I, B | 0.0317058 |
| RIGI | RNA sensor RIG-I | 0.0316067 |
| PKM | pyruvate kinase, muscle | 0.031239 |
| B2M | beta-2-microglobulin | 0.0307596 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0307299 |
| GPC5 | glypican 5 | 0.030619 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0288153 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0287322 |
| SKIL | SKI-like proto-oncogene | 0.0280248 |
| HDAC9 | histone deacetylase 9 | 0.0273819 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0259949 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0256038 |
| PDE8A | phosphodiesterase 8A | 0.0247874 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0246996 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0242386 |
| FAM193A | family with sequence similarity 193, member A | 0.0242333 |
| TRIM56 | tripartite motif containing 56 | 0.0240928 |
| NTN4 | netrin 4 | 0.0239276 |
| IER3 | immediate early response 3 | 0.0233131 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0232344 |
| RNF213 | ring finger protein 213 | 0.023179 |
| COL5A1 | collagen, type V, alpha 1 | 0.0229806 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0227536 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0226583 |
| AREG | amphiregulin | 0.0222401 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0221751 |
| RAB31 | RAB31, member RAS oncogene family | 0.0220048 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0219703 |
| HLA-A | major histocompatibility complex, class I, A | 0.0218979 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0217233 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0214207 |
| JMJD1C | jumonji domain containing 1C | 0.0210604 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0208538 |
| PCNX4 | pecanex 4 | 0.0205597 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0205511 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0205007 |
| PODXL | podocalyxin-like | 0.0204798 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0203478 |
| OSMR | oncostatin M receptor | 0.0202468 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0201987 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0198501 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0197954 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0196878 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0195984 |
| SATB2 | SATB homeobox 2 | 0.0194897 |
| TXNIP | thioredoxin interacting protein | 0.0194483 |
| ITGAV | integrin, alpha V | 0.0191668 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0189804 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.018906 |
| CAB39 | calcium binding protein 39 | 0.018724 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0186938 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0186409 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0186335 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0185797 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0185308 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0185042 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0183585 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0183117 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0182673 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0182263 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0181766 |
| SQSTM1 | sequestosome 1 | 0.0180884 |
| ATXN7L1 | ataxin 7-like 1 | 0.0180728 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0178514 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.102309 |
| TPX2 | TPX2, microtubule-associated | -0.0950585 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0949121 |
| CENPF | centromere protein F, 350/400kDa | -0.0808714 |
| GOLGA4 | golgin A4 | -0.0800076 |
| RBM39 | RNA binding motif protein 39 | -0.0745837 |
| NAV2 | neuron navigator 2 | -0.073422 |
| SMYD3 | SET and MYND domain containing 3 | -0.0709938 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0594438 |
| MATR3 | matrin 3 | -0.0592084 |
| SPAG9 | sperm associated antigen 9 | -0.0587582 |
| WAC | WW domain containing adaptor with coiled-coil | -0.058431 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0562128 |
| SNX14 | sorting nexin 14 | -0.0546716 |
| ANLN | anillin, actin binding protein | -0.053692 |
| ZNF292 | zinc finger protein 292 | -0.0528573 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0517034 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0512734 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0506674 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0483782 |
| DIAPH3 | diaphanous-related formin 3 | -0.04764 |
| SETD5 | SET domain containing 5 | -0.0468494 |
| NUP58 | nucleoporin 58 | -0.0463372 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0453853 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0439695 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0436939 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0429967 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0421784 |
| OGA | O-GlcNAcase | -0.0407881 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0404779 |
| YBX3 | Y box binding protein 3 | -0.0398782 |
| KIF4A | kinesin family member 4A | -0.0395817 |
| NKTR | natural killer cell triggering receptor | -0.0394965 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0394756 |
| EXOC4 | exocyst complex component 4 | -0.0384663 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0383173 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.038085 |
| KIF5B | kinesin family member 5B | -0.0376435 |
| CANX | calnexin | -0.0376208 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.037593 |
| PTMA | prothymosin, alpha | -0.0368327 |
| YAP1 | Yes-associated protein 1 | -0.0362142 |
| PHF20 | PHD finger protein 20 | -0.0357903 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0355143 |
| ATM | ATM serine/threonine kinase | -0.0354759 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0351988 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0350088 |
| TNPO1 | transportin 1 | -0.0335051 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0332383 |
| ECT2 | epithelial cell transforming 2 | -0.0331698 |
| HMGB2 | high mobility group box 2 | -0.0331648 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0328096 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0326105 |
| TPR | translocated promoter region, nuclear basket protein | -0.0319088 |
| SEPTIN7 | septin 7 | -0.0318976 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0317137 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0316434 |
| MKI67 | marker of proliferation Ki-67 | -0.0310632 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0309704 |
| CPNE1 | copine I | -0.0309023 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0308478 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0306447 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.030525 |
| HELZ | helicase with zinc finger | -0.0303612 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0302426 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0301336 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0301122 |
| DEK | DEK proto-oncogene | -0.0300827 |
| RRBP1 | ribosome binding protein 1 | -0.0299358 |
| AURKA | aurora kinase A | -0.0298636 |
| ZNF638 | zinc finger protein 638 | -0.0297513 |
| RBM25 | RNA binding motif protein 25 | -0.0297396 |
| AFF4 | AF4/FMR2 family, member 4 | -0.029586 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0294252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0291453 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0290396 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0290042 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0288154 |
| CEP57 | centrosomal protein 57kDa | -0.0288151 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0285296 |
| CENPE | centromere protein E, 312kDa | -0.028436 |
| QKI | QKI, KH domain containing, RNA binding | -0.0282829 |
| KIF23 | kinesin family member 23 | -0.0279961 |
| RSF1 | remodeling and spacing factor 1 | -0.0277911 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0277549 |
| HJURP | Holliday junction recognition protein | -0.0275276 |
| TFG | TRK-fused gene | -0.0274711 |
| FAM13B | family with sequence similarity 13, member B | -0.0274369 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0272279 |
| CLTC | clathrin, heavy chain (Hc) | -0.0271504 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0271344 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0271301 |
| ACER3 | alkaline ceramidase 3 | -0.027065 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0268252 |
| PRR11 | proline rich 11 | -0.0266823 |
| ETNK1 | ethanolamine kinase 1 | -0.0265722 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0264335 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0264167 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0263659 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0262697 |
