| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | LY2090314 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the LY2090314_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.113883 |
| RNF145 | ring finger protein 145 | 0.0384385 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0375334 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.035466 |
| INTS6 | integrator complex subunit 6 | 0.0344138 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0335281 |
| COPA | coatomer protein complex, subunit alpha | 0.0333615 |
| RBM39 | RNA binding motif protein 39 | 0.0324046 |
| ASPH | aspartate beta-hydroxylase | 0.0315259 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0311102 |
| VCL | vinculin | 0.0310158 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0304632 |
| SEPTIN9 | septin 9 | 0.0289743 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0288494 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0287971 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0283677 |
| OGA | O-GlcNAcase | 0.0277125 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0276122 |
| TOP1 | topoisomerase (DNA) I | 0.0256777 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0255197 |
| PALLD | palladin, cytoskeletal associated protein | 0.0253231 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249039 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0248069 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0248059 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0233196 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0232271 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0232131 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0228903 |
| PRELID2 | PRELI domain containing 2 | 0.0226661 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0219078 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0217862 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0215903 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0208372 |
| HELZ | helicase with zinc finger | 0.0205526 |
| ETNK1 | ethanolamine kinase 1 | 0.0202715 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0199607 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0199522 |
| PUM2 | pumilio RNA-binding family member 2 | 0.019582 |
| NPTN | neuroplastin | 0.0194258 |
| IL6ST | interleukin 6 signal transducer | 0.0194153 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.019001 |
| PDE8A | phosphodiesterase 8A | 0.0189085 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.018887 |
| CUL3 | cullin 3 | 0.0187441 |
| NTN4 | netrin 4 | 0.0184948 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0180732 |
| RNF24 | ring finger protein 24 | 0.0178544 |
| FAM3C | family with sequence similarity 3, member C | 0.0176142 |
| TUFT1 | tuftelin 1 | 0.0175877 |
| FERMT2 | fermitin family member 2 | 0.0174312 |
| RAB10 | RAB10, member RAS oncogene family | 0.0172799 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0172634 |
| SCFD1 | sec1 family domain containing 1 | 0.0171415 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0170813 |
| SETD5 | SET domain containing 5 | 0.0169946 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0167871 |
| AHR | aryl hydrocarbon receptor | 0.0165665 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0164768 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0163035 |
| CALR | calreticulin | 0.0162754 |
| ENAH | enabled homolog (Drosophila) | 0.0161128 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0159033 |
| RPL12 | ribosomal protein L12 | 0.0158878 |
| GOLGA4 | golgin A4 | 0.0158789 |
| NEK7 | NIMA-related kinase 7 | 0.0158424 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0156385 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0156342 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0156006 |
| RPS12 | ribosomal protein S12 | 0.0155916 |
| OTUD7B | OTU deubiquitinase 7B | 0.0155746 |
| MT2A | metallothionein 2A | 0.0154939 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0153685 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0153249 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0151877 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0150799 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.014895 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0148702 |
| TFG | TRK-fused gene | 0.0148216 |
| RUNX1 | runt-related transcription factor 1 | 0.014784 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0147223 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0147063 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.01459 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0145628 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0144926 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0144913 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0144764 |
| TMF1 | TATA element modulatory factor 1 | 0.0144141 |
| PCBP2 | poly(rC) binding protein 2 | 0.0143266 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0143193 |
| VMP1 | vacuole membrane protein 1 | 0.0142313 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0142111 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0140269 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0139955 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0139516 |
| PCM1 | pericentriolar material 1 | 0.013929 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0138972 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0138303 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.013739 |
| NUP58 | nucleoporin 58 | 0.0137177 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0135581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.313477 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.22846 |
| FN1 | fibronectin 1 | -0.186805 |
| NRG1 | neuregulin 1 | -0.156841 |
| SQSTM1 | sequestosome 1 | -0.106081 |
| ITGA1 | integrin, alpha 1 | -0.104533 |
| HMGA2 | high mobility group AT-hook 2 | -0.0985869 |
| TMEM156 | transmembrane protein 156 | -0.0762622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0705156 |
| KLHL5 | kelch-like family member 5 | -0.0627933 |
| HLA-B | major histocompatibility complex, class I, B | -0.0623371 |
| TMSB4X | thymosin beta 4, X-linked | -0.0580153 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0576267 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0552902 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0546921 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0457171 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0455132 |
| TMSB10 | thymosin beta 10 | -0.0438201 |
| RAI14 | retinoic acid induced 14 | -0.0434684 |
| S100A6 | S100 calcium binding protein A6 | -0.0414428 |
| NDRG1 | N-myc downstream regulated 1 | -0.0391869 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0383532 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0381479 |
| EFNA5 | ephrin-A5 | -0.0381349 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0368304 |
| STC2 | stanniocalcin 2 | -0.0367849 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0353868 |
| GLIS3 | GLIS family zinc finger 3 | -0.0348696 |
| FTL | ferritin, light polypeptide | -0.0344218 |
| FBN1 | fibrillin 1 | -0.0333569 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0329358 |
| SYT1 | synaptotagmin I | -0.0324533 |
| DUSP6 | dual specificity phosphatase 6 | -0.0321134 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0307675 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0304419 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0296944 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0294522 |
| ACTG1 | actin gamma 1 | -0.0290389 |
| IER3 | immediate early response 3 | -0.0287754 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0284516 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0284195 |
| ETV1 | ets variant 1 | -0.0275211 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0275031 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0272021 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.026833 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0268136 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0262537 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0258522 |
| AOPEP | aminopeptidase O (putative) | -0.0258174 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0256365 |
| CALU | calumenin | -0.0256311 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0254935 |
| SFTPA2 | surfactant protein A2 | -0.0253162 |
| RPL38 | ribosomal protein L38 | -0.0252827 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0252548 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0251929 |
| PLIN2 | perilipin 2 | -0.0249355 |
| TENM4 | teneurin transmembrane protein 4 | -0.0246236 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0246112 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0245148 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0236888 |
| OSMR | oncostatin M receptor | -0.0235367 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0235093 |
| RPL35A | ribosomal protein L35a | -0.0230629 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0229768 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0229079 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0223182 |
| PTMA | prothymosin, alpha | -0.0222725 |
| HMGA1 | high mobility group AT-hook 1 | -0.0221908 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0221184 |
| CCND1 | cyclin D1 | -0.0215859 |
| TXNRD1 | thioredoxin reductase 1 | -0.0211339 |
| DENND5B | DENN/MADD domain containing 5B | -0.0205025 |
| ETV6 | ets variant 6 | -0.0203908 |
| HLA-A | major histocompatibility complex, class I, A | -0.0203609 |
| USP34 | ubiquitin specific peptidase 34 | -0.0202257 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0198692 |
| MX2 | MX dynamin-like GTPase 2 | -0.0198055 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0195489 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0190544 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0190343 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0190001 |
| RNF213 | ring finger protein 213 | -0.0188535 |
| CP | ceruloplasmin (ferroxidase) | -0.0186906 |
| S100A10 | S100 calcium binding protein A10 | -0.0182966 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0182728 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0182401 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0181487 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.018026 |
| TMEM165 | transmembrane protein 165 | -0.0178897 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0175193 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0173781 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0173185 |
| IL6 | interleukin 6 | -0.0170699 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0169055 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0167843 |
| EGR1 | early growth response 1 | -0.0164447 |
| SMAD3 | SMAD family member 3 | -0.0164436 |
| JUN | jun proto-oncogene | -0.0163998 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0161799 |
