LYN Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description LYN proto-oncogene, Src family tyrosine kinase|This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 4067)
External Link http://www.ncbi.nlm.nih.gov/gene/4067
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Genes

45 substrates of the kinase LYN from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AKAP8 A kinase (PRKA) anchor protein 8
BCR breakpoint cluster region
BTK Bruton agammaglobulinemia tyrosine kinase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD19 CD19 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTTN cortactin
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNL drebrin-like
DOK2 docking protein 2, 56kDa
EPOR erythropoietin receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
GCSAM germinal center-associated, signaling and motility
GRIA2 glutamate receptor, ionotropic, AMPA 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
LAT2 linker for activation of T cells family, member 2
LPXN leupaxin
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MCM7 minichromosome maintenance complex component 7
NMT1 N-myristoyltransferase 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PEAK1 pseudopodium-enriched atypical kinase 1
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRKCD protein kinase C, delta
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RGS16 regulator of G-protein signaling 16
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
STAT5A signal transducer and activator of transcription 5A
SYK spleen tyrosine kinase
TRIM28 tripartite motif containing 28
TRPV4 transient receptor potential cation channel, subfamily V, member 4
WAS Wiskott-Aldrich syndrome