| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lapatinib ditosylate perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lapatinib ditosylate_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.143068 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.126706 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0988043 |
| ZNF608 | zinc finger protein 608 | 0.0923852 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0917759 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0884621 |
| TOX | thymocyte selection-associated high mobility group box | 0.0876073 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0811839 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0781683 |
| NFIA | nuclear factor I/A | 0.0751629 |
| ZNF292 | zinc finger protein 292 | 0.0693407 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0665353 |
| JMJD1C | jumonji domain containing 1C | 0.0660246 |
| ZNF638 | zinc finger protein 638 | 0.0652542 |
| COL5A2 | collagen, type V, alpha 2 | 0.0639653 |
| SMYD3 | SET and MYND domain containing 3 | 0.0627109 |
| RCC1 | regulator of chromosome condensation 1 | 0.0586634 |
| NBEAL1 | neurobeachin-like 1 | 0.0552395 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0544937 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0543658 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0539974 |
| UBC | ubiquitin C | 0.0534461 |
| VCL | vinculin | 0.0529165 |
| HELZ | helicase with zinc finger | 0.0520538 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0518854 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.051401 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0497655 |
| OGA | O-GlcNAcase | 0.0493245 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0490576 |
| CABIN1 | calcineurin binding protein 1 | 0.0487899 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.048708 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0480566 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0474606 |
| USP34 | ubiquitin specific peptidase 34 | 0.0472403 |
| AUTS2 | autism susceptibility candidate 2 | 0.0465471 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0455416 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0445105 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0443441 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0433693 |
| UBE3C | ubiquitin protein ligase E3C | 0.0421866 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0408555 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.04056 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0404077 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0401079 |
| NEBL | nebulette | 0.0397774 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0394787 |
| JUN | jun proto-oncogene | 0.0394527 |
| MED13L | mediator complex subunit 13-like | 0.0390174 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.038969 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0389522 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0386915 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0381779 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0381218 |
| YEATS2 | YEATS domain containing 2 | 0.0380228 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0375544 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0367972 |
| RBM33 | RNA binding motif protein 33 | 0.0360469 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.035909 |
| MSI2 | musashi RNA-binding protein 2 | 0.0358552 |
| ADAR | adenosine deaminase, RNA-specific | 0.0355665 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0350901 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0350362 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0347395 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0345551 |
| RPL37A | ribosomal protein L37a | 0.0344101 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0342687 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0340987 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0338968 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0337175 |
| RPL13A | ribosomal protein L13a | 0.0335255 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0334629 |
| HOMER1 | homer scaffolding protein 1 | 0.0333661 |
| EXT1 | exostosin glycosyltransferase 1 | 0.03335 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0331558 |
| RPS12 | ribosomal protein S12 | 0.0329975 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0329656 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0329164 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0329143 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0328209 |
| NFIB | nuclear factor I/B | 0.0324123 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0323571 |
| GYS1 | glycogen synthase 1 (muscle) | 0.032199 |
| RPS3 | ribosomal protein S3 | 0.0321379 |
| PCBP2 | poly(rC) binding protein 2 | 0.0320989 |
| ARFGEF3 | ARFGEF family member 3 | 0.0315236 |
| DST | dystonin | 0.03131 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0312828 |
| PTK2 | protein tyrosine kinase 2 | 0.0312736 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0311639 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0311368 |
| EXOC6B | exocyst complex component 6B | 0.0310359 |
| PDE7A | phosphodiesterase 7A | 0.0310149 |
| NGLY1 | N-glycanase 1 | 0.0306749 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0303532 |
| BBX | bobby sox homolog (Drosophila) | 0.0301581 |
| GNAS | GNAS complex locus | 0.0300815 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0300521 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0297902 |
| PHF21A | PHD finger protein 21A | 0.0297749 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0297024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM3 | teneurin transmembrane protein 3 | -0.0882948 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0623974 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0530518 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.049631 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0493964 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0398567 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0383894 |
| HHIP | hedgehog interacting protein | -0.0354031 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0349335 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0345919 |
| RPS6 | ribosomal protein S6 | -0.0339872 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0336157 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0327153 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0326683 |
| FAT1 | FAT atypical cadherin 1 | -0.0325439 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0313545 |
| PTMA | prothymosin, alpha | -0.0309995 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0301429 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0294631 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0291637 |
| HMGA1 | high mobility group AT-hook 1 | -0.0279968 |
| TXNRD1 | thioredoxin reductase 1 | -0.0275797 |
| NRG1 | neuregulin 1 | -0.0266818 |
| ZFP64 | ZFP64 zinc finger protein | -0.0255311 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0246158 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0242802 |
| EGR1 | early growth response 1 | -0.0241123 |
| ACTG1 | actin gamma 1 | -0.0236698 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0235591 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0234995 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0231471 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0230891 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0230428 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0222378 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0221524 |
| EMP1 | epithelial membrane protein 1 | -0.0217309 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.021166 |
| CENPF | centromere protein F, 350/400kDa | -0.0209244 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0208443 |
| EFNA5 | ephrin-A5 | -0.0205041 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0204492 |
| DCDC2 | doublecortin domain containing 2 | -0.020432 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0203715 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0198461 |
| RPLP1 | ribosomal protein, large, P1 | -0.0197329 |
| HSPA4 | heat shock 70kDa protein 4 | -0.0194474 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0193948 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0193191 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.019175 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0188364 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0187925 |
| PFN1 | profilin 1 | -0.0186631 |
| SALL4 | spalt-like transcription factor 4 | -0.0185428 |
| SHROOM3 | shroom family member 3 | -0.0180572 |
| ZNF121 | zinc finger protein 121 | -0.0179991 |
| HEATR1 | HEAT repeat containing 1 | -0.0179845 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0179526 |
| RAD51B | RAD51 paralog B | -0.0178882 |
| WDR43 | WD repeat domain 43 | -0.0178604 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0178469 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0178222 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0175651 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | -0.0174612 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | -0.0171884 |
| CBX3 | chromobox homolog 3 | -0.0170534 |
| TMEM123 | transmembrane protein 123 | -0.0168296 |
| RBM25 | RNA binding motif protein 25 | -0.0166305 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0165962 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0165924 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.016431 |
| PYGL | phosphorylase, glycogen, liver | -0.016367 |
| CALD1 | caldesmon 1 | -0.016247 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.0162131 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0161554 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0161541 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0160707 |
| CCN2 | cellular communication network factor 2 | -0.0157659 |
| SRP72 | signal recognition particle 72kDa | -0.0156308 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0155369 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0155009 |
| SRPK1 | SRSF protein kinase 1 | -0.0154943 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) | -0.015351 |
| ATP9A | ATPase, class II, type 9A | -0.0152365 |
| MTAP | methylthioadenosine phosphorylase | -0.0152239 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | -0.0151411 |
| DNMBP | dynamin binding protein | -0.014942 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0148434 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0146984 |
| ATXN10 | ataxin 10 | -0.0146115 |
| PUM3 | pumilio RNA binding family member 3 | -0.0145964 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) | -0.0144473 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0144271 |
| TMEM117 | transmembrane protein 117 | -0.014394 |
| PMM2 | phosphomannomutase 2 | -0.0143538 |
| PDCD11 | programmed cell death 11 | -0.014337 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.014248 |
| RPL27A | ribosomal protein L27a | -0.0141855 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0140576 |
| CPA6 | carboxypeptidase A6 | -0.0139629 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0139068 |
