| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lapatinib ditosylate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lapatinib ditosylate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE4 | transducin-like enhancer of split 4 | 0.0768987 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0556945 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0556819 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0477117 |
| RPL23 | ribosomal protein L23 | 0.0437592 |
| PDE10A | phosphodiesterase 10A | 0.0429653 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0382292 |
| MCL1 | myeloid cell leukemia 1 | 0.0375221 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0372935 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0364647 |
| HELZ | helicase with zinc finger | 0.0349915 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0340568 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0326543 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0324484 |
| RPS12 | ribosomal protein S12 | 0.0321232 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0319223 |
| VMP1 | vacuole membrane protein 1 | 0.0308873 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.02944 |
| SEPTIN9 | septin 9 | 0.0287818 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0283747 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283451 |
| FLNB | filamin B, beta | 0.0281128 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0276465 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0275924 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.027468 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0272653 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0267007 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0265951 |
| TUFT1 | tuftelin 1 | 0.0263909 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0263288 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0261358 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0260211 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025064 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0250317 |
| THBS1 | thrombospondin 1 | 0.0248226 |
| RPL13A | ribosomal protein L13a | 0.0246679 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0244937 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0243836 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0240023 |
| RNF213 | ring finger protein 213 | 0.0238798 |
| FAM168A | family with sequence similarity 168, member A | 0.0238253 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0235725 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0233415 |
| FHL2 | four and a half LIM domains 2 | 0.023055 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0228104 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0226869 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0224807 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0223202 |
| FTO | fat mass and obesity associated | 0.0221409 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0220554 |
| CYTH1 | cytohesin 1 | 0.0220451 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0220203 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0217388 |
| WDR1 | WD repeat domain 1 | 0.0216062 |
| FAT1 | FAT atypical cadherin 1 | 0.0215445 |
| HOMER1 | homer scaffolding protein 1 | 0.0213329 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0212273 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.020982 |
| NFIB | nuclear factor I/B | 0.0208671 |
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.0208191 |
| MX2 | MX dynamin-like GTPase 2 | 0.0206409 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0200701 |
| CCNY | cyclin Y | 0.019863 |
| PLPP1 | phospholipid phosphatase 1 | 0.0198195 |
| CSNK1D | casein kinase 1, delta | 0.0198095 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0196321 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0194917 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0194869 |
| STXBP4 | syntaxin binding protein 4 | 0.0189164 |
| TRRAP | transformation/transcription domain-associated protein | 0.0188966 |
| OGA | O-GlcNAcase | 0.0188709 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0187098 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0186756 |
| RUNX1 | runt-related transcription factor 1 | 0.0186222 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0185762 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0183941 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.018384 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.018352 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0183328 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0182901 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0182876 |
| FLNA | filamin A, alpha | 0.0182866 |
| MED13L | mediator complex subunit 13-like | 0.0182728 |
| INTS6 | integrator complex subunit 6 | 0.0181368 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0181326 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0180516 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0179953 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0179854 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0178763 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0178635 |
| RPL3 | ribosomal protein L3 | 0.0177792 |
| PCBP2 | poly(rC) binding protein 2 | 0.017701 |
| LRRC23 | leucine rich repeat containing 23 | 0.0175453 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0174661 |
| CCNG2 | cyclin G2 | 0.0172814 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.017201 |
| RIMBP2 | RIMS binding protein 2 | 0.0170886 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0169983 |
| DUSP10 | dual specificity phosphatase 10 | 0.0168908 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0168401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.262792 |
| IGF2 | insulin-like growth factor 2 | -0.232203 |
| NRG1 | neuregulin 1 | -0.206295 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.151673 |
| LSAMP | limbic system-associated membrane protein | -0.118896 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0873774 |
| PTMA | prothymosin, alpha | -0.0867613 |
| NREP | neuronal regeneration related protein | -0.0671638 |
| VCL | vinculin | -0.0476632 |
| CRH | corticotropin releasing hormone | -0.0462649 |
| COL3A1 | collagen, type III, alpha 1 | -0.0457222 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0410544 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0403279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0400173 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0394445 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0379441 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0379403 |
| VIM | vimentin | -0.0377694 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0377324 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0373027 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0372879 |
| SYT1 | synaptotagmin I | -0.0371755 |
| RPL19 | ribosomal protein L19 | -0.0363429 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0360474 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0360381 |
| RPS6 | ribosomal protein S6 | -0.0360183 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0359342 |
| RAD51B | RAD51 paralog B | -0.0356557 |
| AHR | aryl hydrocarbon receptor | -0.034892 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0334824 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.033241 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.032829 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0325739 |
| COL1A1 | collagen, type I, alpha 1 | -0.0324124 |
| ZNF804A | zinc finger protein 804A | -0.0322359 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0321877 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0316994 |
| CADM2 | cell adhesion molecule 2 | -0.0310434 |
| CUX1 | cut-like homeobox 1 | -0.0304379 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0303557 |
| DIAPH2 | diaphanous-related formin 2 | -0.0300829 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291744 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0281178 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.028065 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0280022 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0279804 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0279424 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0278878 |
| ITGA1 | integrin, alpha 1 | -0.0275988 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0275844 |
| PCDH15 | protocadherin-related 15 | -0.0270515 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0269887 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0268618 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0261443 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0261199 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.026072 |
| CENPF | centromere protein F, 350/400kDa | -0.025912 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.025849 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0256964 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0256609 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0254495 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0251211 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0250883 |
| DNM3 | dynamin 3 | -0.0248921 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0247903 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.024762 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0245407 |
| ATXN10 | ataxin 10 | -0.0244051 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0243948 |
| PCNX4 | pecanex 4 | -0.0242209 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0241351 |
| TRIM24 | tripartite motif containing 24 | -0.0238739 |
| DST | dystonin | -0.0238717 |
| FNBP1 | formin binding protein 1 | -0.0236228 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0232721 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.023141 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.022886 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0227452 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0223436 |
| CCDC47 | coiled-coil domain containing 47 | -0.0221468 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0221326 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0219183 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0218968 |
| RPS24 | ribosomal protein S24 | -0.0214758 |
| FTL | ferritin, light polypeptide | -0.0214229 |
| CDH13 | cadherin 13 | -0.0213646 |
| RPL18 | ribosomal protein L18 | -0.0210633 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0210357 |
| PCDH9 | protocadherin 9 | -0.0209689 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0209235 |
| ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif, 19 | -0.0207453 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0207331 |
| SPAG16 | sperm associated antigen 16 | -0.0206672 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0206589 |
| FGF14 | fibroblast growth factor 14 | -0.020469 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0204198 |
| RPS5 | ribosomal protein S5 | -0.0203859 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.020276 |
| ZNF124 | zinc finger protein 124 | -0.0202363 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0202144 |
