| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lapatinib ditosylate perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lapatinib ditosylate_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.107714 |
| HLA-B | major histocompatibility complex, class I, B | 0.075772 |
| RPS8 | ribosomal protein S8 | 0.0731985 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0697524 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.068962 |
| CD44 | CD44 molecule (Indian blood group) | 0.0685767 |
| MT2A | metallothionein 2A | 0.0679586 |
| RPS12 | ribosomal protein S12 | 0.0649819 |
| MTSS1 | metastasis suppressor 1 | 0.0624382 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0550624 |
| SMAD3 | SMAD family member 3 | 0.0519389 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0491492 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0478779 |
| RPS13 | ribosomal protein S13 | 0.0461459 |
| RPS3 | ribosomal protein S3 | 0.0455435 |
| DOK5 | docking protein 5 | 0.0441734 |
| RPLP2 | ribosomal protein, large, P2 | 0.0440695 |
| B2M | beta-2-microglobulin | 0.0410846 |
| INTS6 | integrator complex subunit 6 | 0.0400589 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0398129 |
| ASPH | aspartate beta-hydroxylase | 0.0395616 |
| RPL37A | ribosomal protein L37a | 0.0393637 |
| EFNA5 | ephrin-A5 | 0.0391647 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0382509 |
| SQSTM1 | sequestosome 1 | 0.036871 |
| RPL26 | ribosomal protein L26 | 0.0362713 |
| RPL11 | ribosomal protein L11 | 0.0361938 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0358302 |
| RPS25 | ribosomal protein S25 | 0.0356362 |
| FNDC3B | fibronectin type III domain containing 3B | 0.034355 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0342245 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0339563 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.033856 |
| SIK3 | SIK family kinase 3 | 0.0337583 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0337008 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0330829 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0329922 |
| TGM2 | transglutaminase 2 | 0.03282 |
| SULF2 | sulfatase 2 | 0.0326967 |
| RPL37 | ribosomal protein L37 | 0.0324071 |
| SEPTIN9 | septin 9 | 0.0318829 |
| LMO7 | LIM domain 7 | 0.0314819 |
| RPS2 | ribosomal protein S2 | 0.0308416 |
| RPL35A | ribosomal protein L35a | 0.029716 |
| IFI44L | interferon-induced protein 44-like | 0.0295374 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0294438 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0279772 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0279083 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0277267 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0273575 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.027102 |
| RPL5 | ribosomal protein L5 | 0.0269869 |
| MT1E | metallothionein 1E | 0.0266232 |
| RPL13A | ribosomal protein L13a | 0.0263315 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0262564 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0258878 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0256758 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0255542 |
| RPS27A | ribosomal protein S27a | 0.025345 |
| AOPEP | aminopeptidase O (putative) | 0.0252112 |
| RPS27 | ribosomal protein S27 | 0.0248349 |
| RPS29 | ribosomal protein S29 | 0.0246576 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0244937 |
| RAI14 | retinoic acid induced 14 | 0.0244798 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0242336 |
| FOXP1 | forkhead box P1 | 0.0241071 |
| RAD51B | RAD51 paralog B | 0.0238132 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0236429 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0236346 |
| RPL23 | ribosomal protein L23 | 0.0232759 |
| KIAA1217 | KIAA1217 | 0.0232402 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0229873 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0228605 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0225805 |
| SMYD3 | SET and MYND domain containing 3 | 0.0224848 |
| BCR | breakpoint cluster region | 0.0222831 |
| RPS17 | ribosomal protein S17 | 0.021965 |
| HDAC9 | histone deacetylase 9 | 0.0217343 |
| FAM107B | family with sequence similarity 107, member B | 0.0216446 |
| NAV2 | neuron navigator 2 | 0.0216194 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0215085 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0211355 |
| ENO1 | enolase 1, (alpha) | 0.0211195 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0209493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0208866 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0208351 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.020589 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0205853 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0203495 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0202825 |
| MSN | moesin | 0.0201328 |
| RPS15 | ribosomal protein S15 | 0.0200789 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0200606 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0199986 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0198612 |
| RPL9 | ribosomal protein L9 | 0.0198303 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0196176 |
| PCDH1 | protocadherin 1 | 0.0195719 |
| ADAR | adenosine deaminase, RNA-specific | 0.0194785 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0193682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.161254 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.151225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115925 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0951268 |
| SULF1 | sulfatase 1 | -0.0914559 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0870897 |
| PTMA | prothymosin, alpha | -0.0820005 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0783133 |
| RBM39 | RNA binding motif protein 39 | -0.0752183 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0707738 |
| TMSB10 | thymosin beta 10 | -0.0635226 |
| AHNAK | AHNAK nucleoprotein | -0.0605238 |
| KRT17 | keratin 17, type I | -0.0594169 |
| ITGA6 | integrin, alpha 6 | -0.0558777 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0528484 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0526279 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0505982 |
| NDRG1 | N-myc downstream regulated 1 | -0.0493992 |
| TMSB4X | thymosin beta 4, X-linked | -0.0492815 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0470694 |
| KRT6A | keratin 6A, type II | -0.0456272 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0453219 |
| GOLGA4 | golgin A4 | -0.044706 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0438626 |
| CANX | calnexin | -0.0437068 |
| WASF2 | WAS protein family, member 2 | -0.0432689 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0426409 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0423915 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0420936 |
| PGK1 | phosphoglycerate kinase 1 | -0.0413218 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.040855 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0406747 |
| OGA | O-GlcNAcase | -0.0383223 |
| EMP1 | epithelial membrane protein 1 | -0.0381286 |
| GNAS | GNAS complex locus | -0.0371847 |
| MORF4L2 | mortality factor 4 like 2 | -0.0367236 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0361694 |
| CLU | clusterin | -0.036148 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0359621 |
| CAVIN1 | caveolae associated protein 1 | -0.0356995 |
| H1-0 | H1.0 linker histone | -0.0356004 |
| PALLD | palladin, cytoskeletal associated protein | -0.0344657 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0343655 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0338535 |
| SQLE | squalene epoxidase | -0.0335452 |
| LMNA | lamin A/C | -0.033533 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0332894 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0330641 |
| HDLBP | high density lipoprotein binding protein | -0.0330013 |
| EZR | ezrin | -0.0329297 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0329172 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0326818 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0320992 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0316131 |
| COPA | coatomer protein complex, subunit alpha | -0.0315859 |
| SRP54 | signal recognition particle 54kDa | -0.0311829 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0310824 |
| C4BPB | complement component 4 binding protein, beta | -0.0307974 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0306683 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0306356 |
| NEK7 | NIMA-related kinase 7 | -0.0299178 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0295109 |
| TAGLN2 | transgelin 2 | -0.0288987 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.028708 |
| GOLGA2 | golgin A2 | -0.0285534 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0283396 |
| CALU | calumenin | -0.0278465 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0272379 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0272378 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0271203 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0270934 |
| BCL2L1 | BCL2-like 1 | -0.0270762 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0270219 |
| GLG1 | golgi glycoprotein 1 | -0.0268173 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0260313 |
| NRG1 | neuregulin 1 | -0.0255928 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.025429 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0251828 |
| ANLN | anillin, actin binding protein | -0.0251718 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.025037 |
| S100A10 | S100 calcium binding protein A10 | -0.0249268 |
| HM13 | histocompatibility (minor) 13 | -0.0247745 |
| PKM | pyruvate kinase, muscle | -0.0246443 |
| CSNK1E | casein kinase 1, epsilon | -0.0245682 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0245363 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0243963 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0243038 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0242435 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0239592 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0238992 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0238482 |
| MYO10 | myosin X | -0.023787 |
| TMEM263 | transmembrane protein 263 | -0.0236272 |
| LIMA1 | LIM domain and actin binding 1 | -0.0232625 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0230935 |
| COG5 | component of oligomeric golgi complex 5 | -0.022811 |
| SPAG9 | sperm associated antigen 9 | -0.0226897 |
| SERINC3 | serine incorporator 3 | -0.0226588 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0224216 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0224011 |
