| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lapatinib ditosylate perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lapatinib ditosylate_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.172049 |
| EXT1 | exostosin glycosyltransferase 1 | 0.14061 |
| RPS12 | ribosomal protein S12 | 0.0873625 |
| RPS3 | ribosomal protein S3 | 0.0852057 |
| RPL37A | ribosomal protein L37a | 0.0759344 |
| RUNX1 | runt-related transcription factor 1 | 0.0634201 |
| RPL26 | ribosomal protein L26 | 0.0606106 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0580837 |
| MYO10 | myosin X | 0.0519314 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0486552 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0470658 |
| RPL13A | ribosomal protein L13a | 0.0430469 |
| INTS6 | integrator complex subunit 6 | 0.0414725 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0396652 |
| NAV3 | neuron navigator 3 | 0.0395796 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0375385 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0365757 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0358256 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0350468 |
| RPS2 | ribosomal protein S2 | 0.0342963 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0335878 |
| RPL6 | ribosomal protein L6 | 0.0304389 |
| RPS27A | ribosomal protein S27a | 0.0301275 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0299247 |
| RPS13 | ribosomal protein S13 | 0.0293129 |
| RPL35A | ribosomal protein L35a | 0.0285599 |
| RPS29 | ribosomal protein S29 | 0.028321 |
| RPS8 | ribosomal protein S8 | 0.0279769 |
| RPS25 | ribosomal protein S25 | 0.0275136 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0274923 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0272453 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0270187 |
| NTM | neurotrimin | 0.0257267 |
| RPL9 | ribosomal protein L9 | 0.0253802 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0251936 |
| HMGA1 | high mobility group AT-hook 1 | 0.0247422 |
| PRKCE | protein kinase C, epsilon | 0.0246623 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0243774 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0230721 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0220914 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0219665 |
| RPS23 | ribosomal protein S23 | 0.0210631 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0210222 |
| EFNA5 | ephrin-A5 | 0.0209429 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0207843 |
| MSN | moesin | 0.0207202 |
| KIAA1217 | KIAA1217 | 0.0206715 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0200976 |
| GRAMD1B | GRAM domain containing 1B | 0.0195007 |
| RPS10 | ribosomal protein S10 | 0.0193282 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0191969 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0189749 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0186394 |
| CORO1C | coronin, actin binding protein, 1C | 0.0184839 |
| RPL5 | ribosomal protein L5 | 0.0183992 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0180366 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0176266 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0174433 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0172779 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0172597 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0169119 |
| NLK | nemo-like kinase | 0.0168077 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0167525 |
| GPHN | gephyrin | 0.0165147 |
| CTBP2 | C-terminal binding protein 2 | 0.0163885 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0163245 |
| CFAP251 | cilia and flagella associated protein 251 | 0.0162393 |
| RPS15A | ribosomal protein S15a | 0.015943 |
| TRIM44 | tripartite motif containing 44 | 0.0158394 |
| ASPH | aspartate beta-hydroxylase | 0.015582 |
| RCC1 | regulator of chromosome condensation 1 | 0.0155005 |
| MEMO1 | mediator of cell motility 1 | 0.01537 |
| FOSL1 | FOS-like antigen 1 | 0.0153492 |
| TFRC | transferrin receptor | 0.015332 |
| RPL27 | ribosomal protein L27 | 0.0152497 |
| HDAC9 | histone deacetylase 9 | 0.0151291 |
| NUP58 | nucleoporin 58 | 0.0148114 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0147004 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0146962 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0146957 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0146799 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0146128 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0145869 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0145473 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0144169 |
| PARD3 | par-3 family cell polarity regulator | 0.0142872 |
| MSR1 | macrophage scavenger receptor 1 | 0.0142247 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0141923 |
| USP34 | ubiquitin specific peptidase 34 | 0.0139513 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0139002 |
| ACVR1 | activin A receptor, type I | 0.01389 |
| CALD1 | caldesmon 1 | 0.0138656 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0138517 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0136451 |
| FLNC | filamin C, gamma | 0.0135272 |
| RPL7A | ribosomal protein L7a | 0.0135205 |
| CDK14 | cyclin-dependent kinase 14 | 0.0134607 |
| LIMA1 | LIM domain and actin binding 1 | 0.0133118 |
| RASA2 | RAS p21 protein activator 2 | 0.0131942 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0130855 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.215039 |
| TMSB10 | thymosin beta 10 | -0.179921 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.134714 |
| PTMA | prothymosin, alpha | -0.1322 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0949556 |
| FTL | ferritin, light polypeptide | -0.0891783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0863435 |
| RPLP1 | ribosomal protein, large, P1 | -0.0862876 |
| MMP12 | matrix metallopeptidase 12 | -0.0839896 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0803625 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0678946 |
| RPS6 | ribosomal protein S6 | -0.0666688 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0540215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.053018 |
| TPM4 | tropomyosin 4 | -0.0518008 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0481603 |
| YBX3 | Y box binding protein 3 | -0.0478229 |
| AHNAK | AHNAK nucleoprotein | -0.0470698 |
| VCL | vinculin | -0.0469698 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0468588 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0463234 |
| PKM | pyruvate kinase, muscle | -0.0441878 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.043294 |
| GPC6 | glypican 6 | -0.0431554 |
| FOXP1 | forkhead box P1 | -0.0425846 |
| RPS4X | ribosomal protein S4, X-linked | -0.0424573 |
| ACTG1 | actin gamma 1 | -0.0415833 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0400146 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0398294 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0395278 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0394944 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0389229 |
| CD44 | CD44 molecule (Indian blood group) | -0.0385792 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0384477 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0384335 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0382947 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0378919 |
| NAV1 | neuron navigator 1 | -0.0375939 |
| CTSB | cathepsin B | -0.0375248 |
| RPL32 | ribosomal protein L32 | -0.0367441 |
| CD109 | CD109 molecule | -0.036235 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0361278 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0355528 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0344911 |
| GNAS | GNAS complex locus | -0.033907 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0337109 |
| CDK6 | cyclin-dependent kinase 6 | -0.0329119 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.032839 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0328055 |
| POTEF | POTE ankyrin domain family, member F | -0.0322148 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0316261 |
| DIAPH3 | diaphanous-related formin 3 | -0.0313832 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0313703 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0313491 |
| RPLP0 | ribosomal protein, large, P0 | -0.0309744 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0306402 |
| RPS19 | ribosomal protein S19 | -0.0305959 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0303738 |
| HAS2 | hyaluronan synthase 2 | -0.0303186 |
| PTCHD4 | patched domain containing 4 | -0.0299341 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0296229 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.028964 |
| LMNA | lamin A/C | -0.0289331 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0287892 |
| ANXA2 | annexin A2 | -0.0283639 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.027828 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0274376 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0273338 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0273093 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0272314 |
| TXNIP | thioredoxin interacting protein | -0.0268271 |
| TPI1 | triosephosphate isomerase 1 | -0.0267756 |
| MT2A | metallothionein 2A | -0.0265237 |
| CANX | calnexin | -0.0259856 |
| SEPTIN7 | septin 7 | -0.0259574 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0257396 |
| MYOF | myoferlin | -0.0253573 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0252616 |
| RBM39 | RNA binding motif protein 39 | -0.0250724 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0247175 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0245442 |
| RPL34 | ribosomal protein L34 | -0.0243159 |
| MXI1 | MAX interactor 1, dimerization protein | -0.024047 |
| NDRG1 | N-myc downstream regulated 1 | -0.02386 |
| KLF6 | Kruppel-like factor 6 | -0.0236509 |
| FRMD6 | FERM domain containing 6 | -0.023643 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0235898 |
| EMP1 | epithelial membrane protein 1 | -0.0232298 |
| H1-0 | H1.0 linker histone | -0.02267 |
| CAVIN1 | caveolae associated protein 1 | -0.022564 |
| CUX1 | cut-like homeobox 1 | -0.0225159 |
| NLGN1 | neuroligin 1 | -0.0224996 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0223867 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0221896 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.02206 |
| KIF5B | kinesin family member 5B | -0.0220023 |
| MAP1B | microtubule-associated protein 1B | -0.0217791 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0217249 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0214558 |
| SMAD3 | SMAD family member 3 | -0.0212023 |
