| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lapatinib ditosylate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lapatinib ditosylate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.165981 |
| PDGFC | platelet derived growth factor C | 0.0777489 |
| HDAC9 | histone deacetylase 9 | 0.0597621 |
| ZNF608 | zinc finger protein 608 | 0.0566325 |
| EGFR | epidermal growth factor receptor | 0.0541614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.043174 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0369486 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0358451 |
| RPS12 | ribosomal protein S12 | 0.0356793 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0354115 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0344318 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0304682 |
| RPL37A | ribosomal protein L37a | 0.0300475 |
| INTS6 | integrator complex subunit 6 | 0.0299733 |
| MACROD2 | MACRO domain containing 2 | 0.0276114 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0271192 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0264036 |
| RPS8 | ribosomal protein S8 | 0.0261393 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0252387 |
| RPS25 | ribosomal protein S25 | 0.0250879 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0244215 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0240941 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0238718 |
| FER1L6 | fer-1-like family member 6 | 0.0237372 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0237309 |
| ANXA3 | annexin A3 | 0.0218645 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0218172 |
| RPL13A | ribosomal protein L13a | 0.021017 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0206714 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0204572 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0201362 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0199859 |
| RPS3 | ribosomal protein S3 | 0.0199096 |
| IGF2 | insulin-like growth factor 2 | 0.0195447 |
| FOXP1 | forkhead box P1 | 0.0194702 |
| RPS13 | ribosomal protein S13 | 0.0184028 |
| RPS2 | ribosomal protein S2 | 0.0182564 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0181873 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0177973 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.0177721 |
| ZNF91 | zinc finger protein 91 | 0.0176129 |
| RPL26 | ribosomal protein L26 | 0.0175292 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0175278 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0173582 |
| MLIP | muscular LMNA-interacting protein | 0.0169814 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0167902 |
| RPL9 | ribosomal protein L9 | 0.0166195 |
| RPL6 | ribosomal protein L6 | 0.0160857 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0159517 |
| SEPTIN9 | septin 9 | 0.0158065 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0158002 |
| RPL23 | ribosomal protein L23 | 0.0157386 |
| AEBP2 | AE binding protein 2 | 0.0156874 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0156317 |
| SGMS2 | sphingomyelin synthase 2 | 0.0155746 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0155468 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.015492 |
| MYO5C | myosin VC | 0.015434 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0153502 |
| CMIP | c-Maf inducing protein | 0.0153484 |
| RPS23 | ribosomal protein S23 | 0.0152121 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0150278 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0149757 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0149391 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0149168 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0148294 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0147277 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0141581 |
| EXOC4 | exocyst complex component 4 | 0.0140825 |
| RPS29 | ribosomal protein S29 | 0.0138695 |
| CCNY | cyclin Y | 0.0137306 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0137161 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0136474 |
| MED13L | mediator complex subunit 13-like | 0.0135805 |
| LRRC7 | leucine rich repeat containing 7 | 0.0133902 |
| FKTN | fukutin | 0.0132983 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0131003 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0128105 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 0.0127085 |
| ELMO1 | engulfment and cell motility 1 | 0.0126871 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0126566 |
| FLNA | filamin A, alpha | 0.0125309 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0125179 |
| CORO1C | coronin, actin binding protein, 1C | 0.0124824 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0124728 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0124021 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0123103 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0122753 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0122752 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0122084 |
| SUMF1 | sulfatase modifying factor 1 | 0.0122019 |
| VPS50 | VPS50 subunit of EARP/GARPII complex | 0.0121909 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0121025 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0118578 |
| YLPM1 | YLP motif containing 1 | 0.0118163 |
| RPL35A | ribosomal protein L35a | 0.0118103 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0117428 |
| FMN1 | formin 1 | 0.0117386 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0114661 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0114599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.455759 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.149223 |
| TMSB4X | thymosin beta 4, X-linked | -0.0986845 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.092228 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0881208 |
| GOLGA4 | golgin A4 | -0.0813991 |
| AHNAK | AHNAK nucleoprotein | -0.0796916 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0691113 |
| TXNRD1 | thioredoxin reductase 1 | -0.0684968 |
| RPS6 | ribosomal protein S6 | -0.068077 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0662525 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0657883 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0655383 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0654274 |
| CCND1 | cyclin D1 | -0.0652593 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0650857 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0643896 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0635789 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0603655 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0594104 |
| S100A6 | S100 calcium binding protein A6 | -0.0552281 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0536088 |
| RPLP1 | ribosomal protein, large, P1 | -0.0525255 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0520787 |
| EVI5 | ecotropic viral integration site 5 | -0.0508603 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0496976 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0494802 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0489744 |
| RPLP0 | ribosomal protein, large, P0 | -0.0474736 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0472617 |
| HDLBP | high density lipoprotein binding protein | -0.0470431 |
| PKM | pyruvate kinase, muscle | -0.0469854 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0467487 |
| LDHA | lactate dehydrogenase A | -0.0465078 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0462136 |
| GNAS | GNAS complex locus | -0.0450834 |
| PGK1 | phosphoglycerate kinase 1 | -0.044835 |
| FLNB | filamin B, beta | -0.0430383 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0416535 |
| BMP10 | bone morphogenetic protein 10 | -0.0415117 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0407646 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0400346 |
| S100A4 | S100 calcium binding protein A4 | -0.0396136 |
| RBM25 | RNA binding motif protein 25 | -0.0386118 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0383232 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0379291 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0379267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0375548 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0369328 |
| RBM39 | RNA binding motif protein 39 | -0.0365062 |
| SBF2 | SET binding factor 2 | -0.0362792 |
| NF1 | neurofibromin 1 | -0.0360807 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0359853 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0358521 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0352453 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0351288 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0348806 |
| RPL19 | ribosomal protein L19 | -0.0347494 |
| MATR3 | matrin 3 | -0.0346125 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0343934 |
| RHOA | ras homolog family member A | -0.0342378 |
| ACTG1 | actin gamma 1 | -0.033882 |
| TPM4 | tropomyosin 4 | -0.0337903 |
| CANX | calnexin | -0.0337354 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0336109 |
| EZR | ezrin | -0.0334017 |
| DPYD | dihydropyrimidine dehydrogenase | -0.033054 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0329743 |
| SEPTIN7 | septin 7 | -0.0328947 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0328214 |
| SET | SET nuclear proto-oncogene | -0.0322164 |
| USP3 | ubiquitin specific peptidase 3 | -0.0318049 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0317665 |
| KIF5B | kinesin family member 5B | -0.0309343 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0307601 |
| RPL4 | ribosomal protein L4 | -0.0307463 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0307086 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0306771 |
| NFIA | nuclear factor I/A | -0.0306307 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0306021 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0305556 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0304725 |
| NEBL | nebulette | -0.0301332 |
| ZNF292 | zinc finger protein 292 | -0.0300036 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0299157 |
| MSI2 | musashi RNA-binding protein 2 | -0.0296436 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0296308 |
| NBEA | neurobeachin | -0.029586 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0295233 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0294422 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.029315 |
| TXNIP | thioredoxin interacting protein | -0.0292706 |
| CBX3 | chromobox homolog 3 | -0.0288669 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0288117 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0287712 |
| DEK | DEK proto-oncogene | -0.0283683 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0283442 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0282096 |
| VDAC1 | voltage-dependent anion channel 1 | -0.028185 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0281449 |
