| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lapatinib ditosylate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lapatinib ditosylate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0781275 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0674994 |
| SMAD3 | SMAD family member 3 | 0.0546901 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0505513 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0505199 |
| FMNL2 | formin-like 2 | 0.049708 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0479976 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0383334 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0373105 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0352954 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0348284 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0339471 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0335764 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0329251 |
| ARRDC3 | arrestin domain containing 3 | 0.0327468 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0327134 |
| CD44 | CD44 molecule (Indian blood group) | 0.032637 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0317772 |
| EMP1 | epithelial membrane protein 1 | 0.0310094 |
| SMYD3 | SET and MYND domain containing 3 | 0.0307287 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0304605 |
| ANXA1 | annexin A1 | 0.0303814 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.030131 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.029418 |
| YAP1 | Yes-associated protein 1 | 0.0290311 |
| RORA | RAR-related orphan receptor A | 0.0277212 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0272696 |
| AHR | aryl hydrocarbon receptor | 0.0257892 |
| LRRC49 | leucine rich repeat containing 49 | 0.0257734 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.025024 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0245662 |
| ANO6 | anoctamin 6 | 0.024411 |
| IPO7 | importin 7 | 0.0243434 |
| UBQLN1 | ubiquilin 1 | 0.0242689 |
| TXNRD1 | thioredoxin reductase 1 | 0.0239211 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0239137 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0238303 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0238119 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0234714 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0232497 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0231074 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0230333 |
| EPAS1 | endothelial PAS domain protein 1 | 0.022867 |
| RUNX1 | runt-related transcription factor 1 | 0.0223609 |
| KIAA1328 | KIAA1328 | 0.0222844 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0221171 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0218992 |
| ASPH | aspartate beta-hydroxylase | 0.0216717 |
| FNIP1 | folliculin interacting protein 1 | 0.021662 |
| CD59 | CD59 molecule, complement regulatory protein | 0.021444 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0212092 |
| OXSR1 | oxidative stress responsive 1 | 0.0210639 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0209255 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0206937 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0205084 |
| SIK2 | salt-inducible kinase 2 | 0.0203741 |
| CRY1 | cryptochrome circadian clock 1 | 0.0200716 |
| GPR107 | G protein-coupled receptor 107 | 0.0198449 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0193786 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0192722 |
| CDCP1 | CUB domain containing protein 1 | 0.019102 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0190402 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0188017 |
| HSPA8 | heat shock 70kDa protein 8 | 0.018774 |
| TSC22D2 | TSC22 domain family, member 2 | 0.018533 |
| NPTN | neuroplastin | 0.0185318 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0184655 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0182701 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0181325 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0181021 |
| NABP1 | nucleic acid binding protein 1 | 0.0180383 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0178977 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0178153 |
| ATP13A3 | ATPase type 13A3 | 0.0176169 |
| JMJD1C | jumonji domain containing 1C | 0.0175311 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0171468 |
| PDE8A | phosphodiesterase 8A | 0.0168893 |
| ATF3 | activating transcription factor 3 | 0.0167164 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0165428 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0164372 |
| GPHN | gephyrin | 0.0162739 |
| ZNF844 | zinc finger protein 844 | 0.0162526 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0159573 |
| NUP98 | nucleoporin 98kDa | 0.015951 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0159138 |
| NBEA | neurobeachin | 0.0158468 |
| IRF1 | interferon regulatory factor 1 | 0.0158405 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0157768 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0156178 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0155571 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0154685 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0154493 |
| YME1L1 | YME1-like 1 ATPase | 0.0151127 |
| FLNA | filamin A, alpha | 0.0150435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0150287 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0150137 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.0149869 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0149644 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0149396 |
| WHRN | whirlin | 0.0148792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.130893 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113365 |
| TMSB10 | thymosin beta 10 | -0.106315 |
| PTMA | prothymosin, alpha | -0.0984067 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0806555 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0793671 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0693073 |
| MT2A | metallothionein 2A | -0.0659823 |
| HMGA2 | high mobility group AT-hook 2 | -0.0542075 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0503241 |
| PRSS23 | protease, serine, 23 | -0.0491036 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0457 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0430023 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0429188 |
| RBM39 | RNA binding motif protein 39 | -0.0426563 |
| ANGPTL4 | angiopoietin-like 4 | -0.0426321 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0409545 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0405671 |
| TPM4 | tropomyosin 4 | -0.0397499 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0391032 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0370919 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361861 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0361562 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0350605 |
| NAV2 | neuron navigator 2 | -0.034979 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0349606 |
| DST | dystonin | -0.034604 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0337668 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0327213 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.032668 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0322241 |
| IER3 | immediate early response 3 | -0.0321972 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0318077 |
| GPC6 | glypican 6 | -0.0318003 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0317918 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0316431 |
| SPAG9 | sperm associated antigen 9 | -0.0314472 |
| RPL31 | ribosomal protein L31 | -0.0311398 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0310243 |
| PGK1 | phosphoglycerate kinase 1 | -0.030919 |
| RAI14 | retinoic acid induced 14 | -0.030835 |
| RPL35A | ribosomal protein L35a | -0.0304109 |
| FTL | ferritin, light polypeptide | -0.0303504 |
| VCL | vinculin | -0.0298922 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0294908 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0287813 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0284621 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0282637 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0279753 |
| SDC4 | syndecan 4 | -0.0274639 |
| TPI1 | triosephosphate isomerase 1 | -0.0272269 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0272025 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0269271 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.026796 |
| LDHA | lactate dehydrogenase A | -0.0267809 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0266379 |
| PARD3 | par-3 family cell polarity regulator | -0.026343 |
| RPS6 | ribosomal protein S6 | -0.0261538 |
| RSF1 | remodeling and spacing factor 1 | -0.0255819 |
| ERBIN | erbb2 interacting protein | -0.0255325 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.025402 |
| MATR3 | matrin 3 | -0.0246385 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0245397 |
| S100A9 | S100 calcium binding protein A9 | -0.0245197 |
| AK1 | adenylate kinase 1 | -0.0244392 |
| S100A10 | S100 calcium binding protein A10 | -0.0243068 |
| BBX | bobby sox homolog (Drosophila) | -0.0241226 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0240962 |
| ACTG1 | actin gamma 1 | -0.0239616 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0239231 |
| RBM25 | RNA binding motif protein 25 | -0.0239105 |
| RPS8 | ribosomal protein S8 | -0.0238396 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0238009 |
| BPTF | bromodomain PHD finger transcription factor | -0.0237405 |
| ATG7 | autophagy related 7 | -0.0235583 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0235196 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0232681 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0232014 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0231384 |
| RACK1 | receptor for activated C kinase 1 | -0.0229725 |
| TAOK3 | TAO kinase 3 | -0.0227287 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0227013 |
| SEPTIN7 | septin 7 | -0.0226147 |
| FBXO11 | F-box protein 11 | -0.0223343 |
| RPS29 | ribosomal protein S29 | -0.0222547 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0222019 |
| H3-3B | H3.3 histone B | -0.0221524 |
| RPL11 | ribosomal protein L11 | -0.0218187 |
| RPL37A | ribosomal protein L37a | -0.0216052 |
| RPL19 | ribosomal protein L19 | -0.0215266 |
| MAP1B | microtubule-associated protein 1B | -0.0212199 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0212072 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0210778 |
| EFNA5 | ephrin-A5 | -0.0210275 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0210001 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.020921 |
| MAP4 | microtubule-associated protein 4 | -0.0208872 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0205606 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0205182 |
